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    Professional Analysis #2

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    SUNY OswegoEducatio

    The Power of Her Voice: Feminist Connections in Mamma Mia and Wicked

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    SUNY OswegoEnglish & Creative Writin

    Jones Beach Energy and Nature Center Project Outline

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    This project examines the Jones Beach Energy and Nature Center, a net-zero environmental education facility in Jones Beach State Park. It focuses on how the Center’s architecture, renewable energy systems, and exhibits demonstrate sustainability and coastal resilience. In a slideshow report, students research and analyze the building’s design, environmental technologies, and its connection to the surrounding coastal ecosystem.N/

    The role of Polr1D in development and disease: insights from Drosophila melanogaster

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    In eukaryotes, two DNA-dependent RNA polymerases (Pols), Pols I and III, are responsible for the bulk of cellular transcription. Pols I and III transcribe the rRNAs incorporated into ribosomes, in a process known as ribosome biogenesis. POLR1D is a shared subunit of Pol I and III, POLR1D heterodimerizes with POLR1C an essential interaction for the function of both Pols. Mutations in POLR1D cause Treacher Collins Syndrome (TCS), a craniofacial disorder that arises from impaired ribosome biogenesis in a neuronal stem cell population. We found that RNAi knockdown of Polr1D in several non-neural Drosophila melanogaster tissues caused developmental defects. Here, we identified that a Drosophila endocrine tissue is especially sensitive to disruptions in Polr1D during development. This work broadens the role of Polr1D, suggesting that disruptions in human Polr1D might impact additional cell types during development. In addition, we utilized a Drosophila model carrying a clinically relevant mutation in Polr1D to evaluate chemical compounds which suppress TCS phenotypes. We experimentally validated the phenotypic rescue of our Drosophila Polr1D mutant larvae with a known chemical suppressor and provided two treatment approaches for high-throughput screening. Our findings highlight the utility of Drosophila as a scalable, genetically tractable platform that bridges the gap between cell-based assays and resource-intensive mammalian models for therapeutic discovery. Finally, we provide bioinformatic and in vivo evidence for three Drosophila POLR1D (dPOLR1D) splice isoform transcripts. Structural modeling indicated that the protein isoforms are completely conserved apart from their N-termini, which vary in length and sequence. In vitro assays showed that longer N-terminal isoforms exhibit reduced binding to dPOLR1C and decrease heterodimer stability. Importantly, we found that the human POLR1D (hPOLR1D) gene also encodes multiple splice variants resulting in unique N-terminal lengths and sequences. hPOLR1D isoforms with longer N-termini showed reduced hPOLR1C binding and decreased heterodimer stability, mirroring the pattern observed in Drosophila and supporting a conserved role for POLR1D isoform N-termini in modulating heterodimer function. Together, these results broaden our understanding of Polr1D in developmental biology, disease modeling, and heterodimer interactions.NAUpstate Medical UniversityBiochemistry & Molecular BiologyPh

    Conductor Installation and Devices (Level 2B)

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    This course covers: * conductor storage, set up, transportation and installation * procedures for cables pulls in raceways and cable trays * National Electrical Code (NEC) requirements including modifications and installations * termination methods for conductors * grounding and bounding of electrical systems, and fuses and circuit breakersFuture of Work Center 2023-2024SUNY Monro

    The Challenge of Engaging Students in Outreach Efforts During Socio-Political Crisis

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    SUNY OswegoPsycholog

    Where the Lion Sleeps

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    VoRSUNY BrockportyesThis publication has been checked against freely available accessibility tools and deemed accessible. Should you have a problem accessing it, please email [email protected] for assistance

    Who said you can't teach an old librarian new tricks?

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    Sometimes, we need more than a spreadsheet. This session will cover methods to create attractive and persuasive data visualizations using data exported from analyses created in Alma Analytics. Attendees can expect an introduction to multiple open-source Python libraries which make creating data visualizations swift and intuitive. The examples will include visualizations of data from Alma Analytics analyses of SUNY Maritime's print and electronic collections. All code will be created in Google Colab and demonstrated live so that attendees may follow along. After the session, attendees can expect to feel confident creating simple data visualizations to better communicate with faculty, colleagues, and administration. The level of instruction will be geared towards professionals who have little to no prior experience with Python, but all are welcome.SUNY Maritime CollegeLibraryye

    The History of Hyperbolic Geometry Through the Study of Curvature

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    SUNY OswegoMathematic

    Power and Resistance in the Faculty-Student Relationship

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    SUNY OswegoStrategic Communicatio

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