Investigation of the Effect of Pore Size on Mechanical Properties of Open Cell Aluminium Foam Structure

Al foams with different pore size were developed through infiltration process by foundry technology and characterization of the developed Al foams for their density, porosity and compression strength. Al foams were produced through infiltration process by open metal die casting using soil granules of different diameter as space holder particles (SHP). The SHP balls were removed from the Al foam by water jet along with vibration. The density and porosity were measured by theoretically and experimentally. The compression tests were conducted on developed Al foams of different densities using universal testing machine. Developed Al foam density varies from 0.9g/cc to 1.2g/cc, the porosity varies from 54% to 65% and compressive behaviour showed the plateaus stress was directly proportional to SHP ball size in Al foams

Grouping predictors via network-wide metrics

When multitudes of features can plausibly be associated with a response, both privacy considerations and model parsimony suggest grouping them to increase the predictive power of a regression model. Specifically, the identification of groups of predictors significantly associated with the response variable eases further downstream analysis and decision-making. This paper proposes a new data analysis methodology that utilizes the high-dimensional predictor space to construct an implicit network with weighted edges %and weights on the edges to identify significant associations between the response and the predictors. Using a population model for groups of predictors defined via network-wide metrics, a new supervised grouping algorithm is proposed to determine the correct group, with probability tending to one as the sample size diverges to infinity. For this reason, we establish several theoretical properties of the estimates of network-wide metrics. A novel model-assisted bootstrap procedure that substantially decreases computational complexity is developed, facilitating the assessment of uncertainty in the estimates of network-wide metrics. The proposed methods account for several challenges that arise in the high-dimensional data setting, including (i) a large number of predictors, (ii) uncertainty regarding the true statistical model, and (iii) model selection variability. The performance of the proposed methods is demonstrated through numerical experiments, data from sports analytics, and breast cancer data

New approaches to measuring anthelminthic drug efficacy: parasitological responses of childhood schistosome infections to treatment with praziquantel

By 2020, the global health community aims to control and eliminate human helminthiases, including schistosomiasis in selected African countries, principally by preventive chemotherapy (PCT) through mass drug administration (MDA) of anthelminthics. Quantitative monitoring of anthelminthic responses is crucial for promptly detecting changes in efficacy, potentially indicative of emerging drug resistance. Statistical models offer a powerful means to delineate and compare efficacy among individuals, among groups of individuals and among populations.; We illustrate a variety of statistical frameworks that offer different levels of inference by analysing data from nine previous studies on egg counts collected from African children before and after administration of praziquantel.; We quantify responses to praziquantel as egg reduction rates (ERRs), using different frameworks to estimate ERRs among population strata, as average responses, and within strata, as individual responses. We compare our model-based average ERRs to corresponding model-free estimates, using as reference the World Health Organization (WHO) 90 % threshold of optimal efficacy. We estimate distributions of individual responses and summarize the variation among these responses as the fraction of ERRs falling below the WHO threshold.; Generic models for evaluating responses to anthelminthics deepen our understanding of variation among populations, sub-populations and individuals. We discuss the future application of statistical modelling approaches for monitoring and evaluation of PCT programmes targeting human helminthiases in the context of the WHO 2020 control and elimination goals

An unusual case of anti-neutrophilic cytoplasmic autoantibodies associated vasculitis with pauci-immune crescentic glomerulonephritis in young? Wegener’s? Churg Strauss

Anti-neutrophilic cytoplasmic autoantibodies-associated vasculitis (AAV) is very rare in India. It normally affects older population around 6th and 7th decade of life. The management of cases is also complicated. We present a case of 18 year old male patient who came with complaints of epistaxis and had hematuria and pain in the joints. He had sub conjunctival haemorrhage on presentation. On and off he had respiratory symptoms and epistaxis in the past for which he was treated as allergy and bronchial asthma. At admission he had high absolute eosinophil count and had blood 3+ positive in urine. Initially he was treated as post viral vasculitis. But patient had involvement of kidney, lung, skin, joints, eyes and on further evaluation he was found to have AAV. The case was unique due to the age of presentation and patient also had overlapping symptoms of both Wegner’s granulomatosis and Churg-Strauss syndrome

<span style="font-size:11.0pt;font-family: "Times New Roman";mso-fareast-font-family:"Times New Roman";mso-bidi-font-family: Mangal;mso-ansi-language:EN-GB;mso-fareast-language:EN-US;mso-bidi-language: HI" lang="EN-GB">Elevated levels of saturated and unsaturated fatty acids highlight the nutritional value of <i style="mso-bidi-font-style:normal">Ulva covalengensis, </i><span style="mso-bidi-font-style:italic">a<i style="mso-bidi-font-style:normal"> </i>marine dietary alga found in south India.</span></span>

120-124<span style="font-size:11.0pt;font-family: " times="" new="" roman";mso-fareast-font-family:"times="" roman";mso-bidi-font-family:="" mangal;mso-ansi-language:en-gb;mso-fareast-language:en-us;mso-bidi-language:="" hi"="" lang="EN-GB">Gas chromatography coupled to mass spectrometry (GC-MS) is applied to examine the relative levels of saturated and unsaturated fatty acids in two species of coastally-derived edible algae Ulva covalengensis and Enteromorpha flexuosa and compared their profiles with those of non-edible algae Chaetomorpha antennina and Grateloupia lithophyla. Present study reveals elevated levels of fatty acids in Ulva covalengensis that included higher levels of arachadonic acid, the precursor of prostaglandin, source of energy and component of cell membranes. </span

Ore petrology of the V-Ti magnetite (lodestone) layers of the Kurihundi area of Sargur schist belt, Dharwar craton

The V-Ti magnetite layers (lodestone) occur within the layered gabbro-anorthosites-ultramafic rocks emplaced into the migmatitic gneisses close to the high grade Archeaen Sargur supracrustal rocks in the Kurihundi area. The ore petrographic studies of the lodestone reveal the presence of primary Ti-magnetite, ilmenite, ulvospinel, pleonaste, hematite and pyrite, chalcopyrite, pyrrhotite and secondary Ti-maghemite, martite and goethite as well as secondary covellite. These layers contain Ti-magnetite (60%) and ilmenite (30%) with silicates (< 5%) exhibiting granular mosaic texture with well-defined triple junctions and are classified as adcumulus rocks. The grain-boundary relationships in the ores indicate considerable postcumulus growth and readjustment due to combined effects of sintering and adcumulus growth. Intergrowth textures (ulvospinel, ilmenite and pleonaste in Ti-magnetite and hematite in ilmenite) reflects exsolution features crystallized from solid-solutions compositions under different conditions of oxygen fugacities. Larger bodies of pleonaste and ilmenite in Ti-magnetite become lensoid or rounded in outline and these morphological modifications took place during the regional upper amphibolite to lower granulite facies metamorphism at 2.6 Ga ago. The lodestone contains high TiO(2) (20 to 22.59 wt%), with V(2)O(5) (0.85 to 1.15%) and Fe(2)O(3) (t) (72.03 to 74.25%). Ti-magnetite shows alteration to Ti-maghemite, martite and goethite due to low temperature oxidation and hydration during weathering

Acute nontraumatic upper limb ischaemia: A protocol for management

Aim: To determine the role of different modalities available and draw guidelines for the treatment of acute ischaemia of the upper limb. Materials and Method: This is a retrospective study carried out over a period of 7 years between 1994-2000 comparing embolectomy with thrombolytic therapy for upper limb ischaemia. Twenty-two patients presenting with acute upper limb ischaemia admitted in this hospital were studied. Their age, sex distribution, symptoms and associated medical illnesses were documented. Pain was the predominant symptom in most of them. The underlying causes were treated accordingly in the form of excision of cervical rib or high first rib, angioplasty and stenting. Results: The overall success rate was 91% (n = 20) with an amputation rate of 9%. In the surgical group (ten patients), seven patients responded well. Two patients recovered with further thrombolytic therapy. One patient underwent amputation. In the thrombolytic therapy group (ten patients), six patients responded to thrombolytic therapy alone. The rest of them recovered with further embolectomy. Conclusion: Thrombolytic therapy can thus be the first modality of treatment for acute nontraumatic upper limb ischaemia if the limb is viable