1,422 research outputs found
Correlated noise in networks of gravitational-wave detectors: subtraction and mitigation
One of the key science goals of advanced gravitational-wave detectors is to
observe a stochastic gravitational-wave background. However, recent work
demonstrates that correlated magnetic fields from Schumann resonances can
produce correlated strain noise over global distances, potentially limiting the
sensitivity of stochastic background searches with advanced detectors. In this
paper, we estimate the correlated noise budget for the worldwide Advanced LIGO
network and conclude that correlated noise may affect upcoming measurements. We
investigate the possibility of a Wiener filtering scheme to subtract correlated
noise from Advanced LIGO searches, and estimate the required specifications. We
also consider the possibility that residual correlated noise remains following
subtraction, and we devise an optimal strategy for measuring astronomical
parameters in the presence of correlated noise. Using this new formalism, we
estimate the loss of sensitivity for a broadband, isotropic stochastic
background search using 1 yr of LIGO data at design sensitivity. Given our
current noise budget, the uncertainty with which LIGO can estimate energy
density will likely increase by a factor of ~4--if it is impossible to achieve
significant subtraction. Additionally, narrowband cross-correlation searches
may be severely affected at low frequencies f < 45 Hz without effective
subtraction.Comment: 16 pages, 8 figure
Weighted Modal Transition Systems
Specification theories as a tool in model-driven development processes of
component-based software systems have recently attracted a considerable
attention. Current specification theories are however qualitative in nature,
and therefore fragile in the sense that the inevitable approximation of systems
by models, combined with the fundamental unpredictability of hardware
platforms, makes it difficult to transfer conclusions about the behavior, based
on models, to the actual system. Hence this approach is arguably unsuited for
modern software systems. We propose here the first specification theory which
allows to capture quantitative aspects during the refinement and implementation
process, thus leveraging the problems of the qualitative setting.
Our proposed quantitative specification framework uses weighted modal
transition systems as a formal model of specifications. These are labeled
transition systems with the additional feature that they can model optional
behavior which may or may not be implemented by the system. Satisfaction and
refinement is lifted from the well-known qualitative to our quantitative
setting, by introducing a notion of distances between weighted modal transition
systems. We show that quantitative versions of parallel composition as well as
quotient (the dual to parallel composition) inherit the properties from the
Boolean setting.Comment: Submitted to Formal Methods in System Desig
Brain edema : a valid endpoint for measuring hepatic encephalopathy?
Hepatic encephalopathy (HE) is a major complication of liver failure/disease which frequently develops during the progression of end-stage liver disease. This metabolic neuropsychiatric syndrome involves a spectrum of symptoms, including cognition impairment, attention deficits and motor dysfunction which eventually can progress to coma and death. Pathologically, HE is characterized by swelling of the astrocytes which consequently leads to brain edema, a common feature found in patients with acute liver failure (ALF) as well as in cirrhotic patients suffering from HE. The pathogenic factors involved in the onset of astrocyte swelling and brain edema in HE are unresolved. However, the role of astrocyte swelling/brain edema in the development of HE remains ambiguous and therefore measuring brain edema as an endpoint to evaluate HE is questioned. The following review will determine the effect of astrocyte swelling and brain edema on neurological function, discuss the various possible techniques to measure brain edema and lastly to propose a number of neurobehavioral tests to evaluate HE
Correlated magnetic noise in global networks of gravitational-wave detectors: Observations and implications
One of the most ambitious goals of gravitational-wave astronomy is to observe the stochastic gravitational-wave background. Correlated noise in two or more detectors can introduce a systematic error, which limits the sensitivity of stochastic searches. We report on measurements of correlated magnetic noise from Schumann resonances at the widely separated LIGO and Virgo detectors. We investigate the effect of this noise on a global network of gravitational-wave detectors and derive a constraint on the allowable coupling of environmental magnetic fields to test mass motion in gravitational-wave detectors. We find that while correlated noise from global electromagnetic fields could be safely ignored for initial LIGO stochastic searches, it could severely impact Advanced LIGO, Advanced Virgo, KAGRA, as well as third-generation detectors
Identification of potentially safe promising fungal cell factories for the production of polyketide natural food colorants using chemotaxonomic rationale
Gravitational-wave astronomy with a physical calibration model
We carry out astrophysical inference for compact binary merger events in LIGO-Virgo’s first gravitational-wave transient catalog (GWTC-1) using a physically motivated calibration model. We demonstrate that importance sampling can be used to reduce the cost of what would otherwise be a computationally challenging analysis for signal-to-noise ratios of current gravitational-wave detections. We show that including the physical estimate for the calibration error distribution has negligible impact on the inference of parameters for the events in GWTC-1. Studying a simulated signal with matched filter signal-to-noise ratio
SNR = 200, we project that a calibration error estimate typical of GWTC-1 is likely to be negligible for the current generation of gravitational-wave detectors. We argue that other sources of systematic error—from waveforms, prior distributions, and noise modeling—are likely to be more important. Finally, using the events in GWTC-1 as standard sirens, we infer an astrophysically informed improvement on the estimate of the calibration error in the LIGO interferometers
Application of WGS data for O-specific antigen analysis and <i>in silico </i>serotyping of <i>Pseudomonas aeruginosa </i>isolates
Accurate typing methods are required for efficient infection control. The emergence of whole-genome sequencing (WGS) technologies has enabled the development of genome-based methods applicable for routine typing and surveillance of bacterial pathogens. In this study, we developed the Pseudomonas aeruginosa serotyper (PAst) program, which enabled in silico serotyping of P. aeruginosa isolates using WGS data. PAst has been made publically available as a web service and aptly facilitates high-throughput serotyping analysis. The program overcomes critical issues such as the loss of in vitro typeability often associated with P. aeruginosa isolates from chronic infections and quickly determines the serogroup of an isolate based on the sequence of the O-specific antigen (OSA) gene cluster. Here, PAst analysis of 1,649 genomes resulted in successful serogroup assignments in 99.27% of the cases. This frequency is rarely achievable by conventional serotyping methods. The limited number of nontypeable isolates found using PAst was the result of either a complete absence of OSA genes in the genomes or the artifact of genomic misassembly. With PAst, P. aeruginosa serotype data can be obtained from WGS information alone. PAst is a highly efficient alternative to conventional serotyping methods in relation to outbreak surveillance of serotype O12 and other high-risk clones, while maintaining backward compatibility to historical serotype data
Gravitational waves from Sco X-1: A comparison of search methods and prospects for detection with advanced detectors
The low-mass X-ray binary Scorpius X-1 (Sco X-1) is potentially the most
luminous source of continuous gravitational-wave radiation for interferometers
such as LIGO and Virgo. For low-mass X-ray binaries this radiation would be
sustained by active accretion of matter from its binary companion. With the
Advanced Detector Era fast approaching, work is underway to develop an array of
robust tools for maximizing the science and detection potential of Sco X-1. We
describe the plans and progress of a project designed to compare the numerous
independent search algorithms currently available. We employ a mock-data
challenge in which the search pipelines are tested for their relative
proficiencies in parameter estimation, computational efficiency, robust- ness,
and most importantly, search sensitivity. The mock-data challenge data contains
an ensemble of 50 Scorpius X-1 (Sco X-1) type signals, simulated within a
frequency band of 50-1500 Hz. Simulated detector noise was generated assuming
the expected best strain sensitivity of Advanced LIGO and Advanced VIRGO ( Hz). A distribution of signal amplitudes was then
chosen so as to allow a useful comparison of search methodologies. A factor of
2 in strain separates the quietest detected signal, at
strain, from the torque-balance limit at a spin frequency of 300 Hz, although
this limit could range from (25 Hz) to (750 Hz) depending on the unknown frequency of Sco X-1. With future
improvements to the search algorithms and using advanced detector data, our
expectations for probing below the theoretical torque-balance strain limit are
optimistic.Comment: 33 pages, 11 figure
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