Observation of a γ\gamma-band based on two-quasiparticle configuration in 70^{70}Ge

The structure of $^{70}$Ge has been studied through in-beam gamma ray spectroscopy. A new band structure is identified that leads to forking of the ground-state band into two excited bands. Band structures have been investigated using the microscopic triaxial projected shell model approach. The observed forking is demonstrated to result from almost simultaneous band crossing of the two neutron aligned and the \gamma-band built on this two-quasiparticle configuration with the ground-state band.Comment: 9 pages, 13 figures, Accepted for publication as a Regular Article in PRC. in Physical Review C, 24th Feb 201

Qualitative Analysis of Subsurface Water Quality in Challakere Taluk, Karnataka, India

Rural India relies mainly on groundwater for drinking and agriculture. Unsustainable withdrawal of groundwater has led to the spectra of depleting the problem of water scarcity. The available groundwater quality is not only contaminated by hazardous pathogenic germs and anthropogenic substances but also geogenic substances is adversely affect the water supply of many regions. The groundwater of Challakere taluk had many threats such as anthropogenic activities, quality deterioration by agricultural activities and over exploitation and also persistence of continuous drought condition. This paper mainly addresses the physico-chemical concentration of 30 groundwater samples during August 2009 in Challakere taluk, Karnataka (India). The results of all the findings are discussed in details which reflect the present status of the groundwater quality of the study area. Groundwater is extremely important to the future economy and growth of rural India. If the resource is to remain available as high quality water for future generation it is important to protect from possible contamination. Hence it is recommended that suitable water quality management is essential to avoid any further contamination

Cathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infection

Lysosomal cathepsins regulate an exquisite range of biological functions, and their deregulation is associated with inflammatory, metabolic, and degenerative diseases in humans. In this study, we identified a key cell-intrinsic role for cathepsin B as a negative feedback regulator of lysosomal biogenesis and autophagy. Mice and macrophages lacking cathepsin B activity had increased resistance to the cytosolic bacterial pathogen Francisella novicida. Genetic deletion or pharmacological inhibition of cathepsin B down-regulated mechanistic target of rapamycin activity and prevented cleavage of the lysosomal calcium channel TRP ML1. These events drove transcription of lysosomal and autophagy genes via transcription factor EB, which increased lysosomal biogenesis and activation of autophagy initiation kinase ULK1 for clearance of the bacteria. Our results identified a fundamental biological function of cathepsin B in providing a checkpoint for homeostatic maintenance of lysosome populations and basic recycling functions in the cell

Bilateral pulmonary metastases of papillary thyroid carcinoma in a 12-year-old child-A case report and review of the literature.

Metastatic disease of the lung has been extensively documented in the adult patient population. The most common primary sources for pulmonary metastases include breast, colon gastrointestinal including pancreas and urinary bladder. Malignant lung tumors in pediatric population is extremely rare. However, like in adult patient population, metastases are more common than primary tumors in lung in pediatric patients. Metastatic spread of tumors can occur both by way of hematogenous spread and lymphatic pathways. We present a rare case of biopsy proven metastatic thyroid carcinoma in the lung in a 12-year-old male child masquerading as bilateral miliary nodules on imaging studies. The importance of recognition of this entity in terms of prognosis and treatment is discussed

Scheduling Data Intensive Workloads through Virtualization on MapReduce based Clouds

MapReduce has become a popular programming model for running data intensive applications on the cloud. Completion time goals or deadlines of MapReduce jobs set by users are becoming crucial in existing cloud-based data processing environments like Hadoop. There is a conflict between the scheduling MR jobs to meet deadlines and "data locality" (assigning tasks to nodes that contain their input data). To meet the deadline a task may be scheduled on a node without local input data for that task causing expensive data transfer from a remote node. In this paper, a novel scheduler is proposed to address the above problem which is primarily based on the dynamic resource reconfiguration approach. It has two components: 1) Resource Predictor: which dynamically determines the required number of Map/Reduce slots for every job to meet completion time guarantee; 2) Resource Reconfigurator: that adjusts the CPU resources while not violating completion time goals of the users by dynamically increasing or decreasing individual VMs to maximize data locality and also to maximize the use of resources within the system among the active jobs. The proposed scheduler has been evaluated against Fair Scheduler on virtual cluster built on a physical cluster of 20 machines. The results demonstrate a gain of about 12% increase in throughput of Job

ICHTHYOFAUNAL DIVERSITY IN DUGLAPURA LAKE OF CHIKMAGALUR DISTRICT, KARNATAKA

The fishes plays an important role in human health and national economy. The current study was undertaken with the purpose of assessing the fish diversity in Duglapura lake of Chikmagalur district, Karnataka during June to December 2009. The present study has shown that lake supports low fish diversity and hence 12 fish species were recorded belonging to 4 orders, 6 families and 11 genera. Among the families Cyprinidae was the most dominant in the assemblage composition with 58.33% and rest of the families viz., Channidae, Cichlidae, Gobiidae, Notopteridae and Heteropneustidae each with 8.33% respectively. As far as Biodiversity status is concerned (IUCN-1994), 05 fish species are categorized into LR-nt, 3 Not assessed 3 Vulnerable and one as LR-lc respectively. Economic value of fishes is discussed in this paper. Therefore, for the proper management and utilization of this fish wealth, it is necessary to take up the sustainable steps to monitor and conserve this fish health in this lake

COMPARATIVE STUDY ON FISH DIVERSITY IN TWO LENTIC WATER BODIES OF BHADRAVATHI TALUK, KARNATAKA

The fish diversity of the Nagappanakere tank and Kudligere tank in relation to physico-chemical parameters was studied by monthly samples taken from February 2010 to January 2011. In this study, Nagappanakere tank supported 13 fish species belonging to 04 orders, 06 families and 12 genera. While, Kudligere tank supported 18 fish species belonging to 04 orders, 07 families and 15 genera. Among fish families Cyprinidae was dominant in both the water bodies. In Nagappanakere tank as far as biodiversity status (IUCN-1994) is concerned, 03 species is Not assessed (23.08 %), 06 species as lower risk-near threatened (46.15 %), vulnerable 02 species (15.38%), lower risk least concern is one (7.70%) and 01 species included under the category of Data deficient (7.69%). However, in Kudligere tank 01 species is endangered (5.55 %), 07 species as lower risk-near threatened (38.89 %), vulnerable 02 species (11.11%), lower risk least concern is one (5.55%) , 06 species included under the category of Not assessed (33.33%) and 01 species consider as Data deficient with 5.55%. Physico-chemical characteristics responsible for the occurrence and distribution of fishes in these water bodies are discussed. Hence, proper management and utilization of this fish wealth is necessary to take up the sustainable steps to monitor and conserve fish health

Natural occurrence of ochratoxin A contamination in commercial black and white pepper products.

The concentration of ochratoxin A (OTA) in 120 commercial pepper (84 pre-packed and 36 bulk samples), which consist of local and imported white and black pepper in powder and seed form in Malaysia were determined. The objective of the study was to investigate and compare OTA concentration in black pepper and white pepper being commercialized in Malaysia. Determination method was based on HPLC with fluorescence detection coupled with immunoaffinity column clean-up step. Mobile phase consisted of acetonitrile-water-acetic acid (49.5:49.5:1.0, v/v/v), and flow rate was 1 ml/min. The LOD was 0.02 ng/g, and the average recovery values of OTA ranged from 79.5 to 92.0% in black pepper and 81.2-90.3% in white pepper. A total of 57 samples (47.5%) were contaminated with OTA ranging from 0.15 to 13.58 ng/g. The results showed that there was a significant difference between type of pepper and brands. OTA concentration in black pepper was significantly higher than white pepper (p < 0.05). The highest concentration of ochratoxin, 13.58 ng/g, was detected in a sample of black pepper seed followed by 12.64 ng/g in a sample of black pepper powder, both were bulk samples purchased from open market

Difeerentiation Of Water {Physical, Chemical} Parmeters In Kachapoor Lake, Sarampally -Kamareddy Lake, Biknoor Lake.

The research paper extensively covers the phenomenon of bioaccumulation, focusing on its impact in freshwater ecosystems, particularly on fish. It details how heavy metals like mercury, lead, cadmium, and arsenic, originating from industrial pollution, agricultural runoff, and atmospheric deposition, accumulate in fish tissues over time. The abstract highlights the adverse effects of such bioaccumulation on fish health, including reproduction issues, growth abnormalities, and organ damage. It also underscores the consequent risks to human health when these contaminated fish are consumed. The study emphasizes the importance of addressing heavy metal pollution in aquatic ecosystems through effective waste management, reduction of industrial discharges, sustainable agricultural practices, and regular monitoring of fish populations. This approach is crucial to manage and mitigate the risks of heavy metal bioaccumulation in freshwater fish, thereby protecting both aquatic life and human health