1,168 research outputs found
Multiple G-It\^{o} integral in the G-expectation space
In this paper, motivated by mathematic finance we introduce the multiple
G-It\^{o} integral in the G-expectation space, then investigate how to
calculate. We get the the relationship between Hermite polynomials and multiple
G-It\^{o} integrals which is a natural extension of the classical result
obtained by It\^{o} in 1951.Comment: 9 page
There is no Nontrivial Hedging Portfolio for Option Pricing with Transaction Costs
Conventional wisdom holds that since continuous-time, Black-Scholes hedging is infinitely expensive in a model with proportional transaction costs, there is no continuous-time strategy which hedges a European call option perfectly. Of course, if one is attempting to dominate the European call rather than replicate it, then one can use the trivial strategy of buying one share of the underlying stock and holding to maturity. In this paper we prove that this is, in fact, the least expensive method of dominating a European call in a Black-Scholes model with proportional transaction costs
On the existence and uniqueness of solutions to stochastic differential equations driven by G-Brownian motion with integral-Lipschitz coefficients
In this paper, we study the existence and uniqueness of solutions to
stochastic differential equations driven by G-Brownian motion (GSDEs) with
integral-Lipschitz conditions on their coefficients
An overview of Viscosity Solutions of Path-Dependent PDEs
This paper provides an overview of the recently developed notion of viscosity
solutions of path-dependent partial di erential equations. We start by a quick
review of the Crandall- Ishii notion of viscosity solutions, so as to motivate
the relevance of our de nition in the path-dependent case. We focus on the
wellposedness theory of such equations. In partic- ular, we provide a simple
presentation of the current existence and uniqueness arguments in the
semilinear case. We also review the stability property of this notion of
solutions, in- cluding the adaptation of the Barles-Souganidis monotonic scheme
approximation method. Our results rely crucially on the theory of optimal
stopping under nonlinear expectation. In the dominated case, we provide a
self-contained presentation of all required results. The fully nonlinear case
is more involved and is addressed in [12]
Vortex density models for superconductivity and superfluidity
We study some functionals that describe the density of vortex lines in
superconductors subject to an applied magnetic field, and in Bose-Einstein
condensates subject to rotational forcing, in quite general domains in 3
dimensions. These functionals are derived from more basic models via
Gamma-convergence, here and in a companion paper. In our main results, we use
these functionals to obtain descriptions of the critical applied magnetic field
(for superconductors) and forcing (for Bose-Einstein), above which ground
states exhibit nontrivial vorticity, as well as a characterization of the
vortex density in terms of a non local vector-valued generalization of the
classical obstacle problem.Comment: 34 page
Some flows in shape optimization
Geometric flows related to shape optimization problems of Bernoulli type are
investigated. The evolution law is the sum of a curvature term and a nonlocal
term of Hele-Shaw type. We introduce generalized set solutions, the definition
of which is widely inspired by viscosity solutions. The main result is an
inclusion preservation principle for generalized solutions. As a consequence,
we obtain existence, uniqueness and stability of solutions. Asymptotic behavior
for the flow is discussed: we prove that the solutions converge to a
generalized Bernoulli exterior free boundary problem
Convergence of Ginzburg-Landau functionals in 3-d superconductivity
In this paper we consider the asymptotic behavior of the Ginzburg- Landau
model for superconductivity in 3-d, in various energy regimes. We rigorously
derive, through an analysis via {\Gamma}-convergence, a reduced model for the
vortex density, and we deduce a curvature equation for the vortex lines. In a
companion paper, we describe further applications to superconductivity and
superfluidity, such as general expressions for the first critical magnetic
field H_{c1}, and the critical angular velocity of rotating Bose-Einstein
condensates.Comment: 45 page
CD38/cADPR Signaling Pathway in Airway Disease: Regulatory Mechanisms
Asthma is an inflammatory disease in which proinflammatory cytokines have a role in inducing abnormalities of airway smooth muscle function and in the development of airway hyperresponsiveness. Inflammatory cytokines alter calcium (Ca2+) signaling and contractility of airway smooth muscle, which results in nonspecific airway hyperresponsiveness to agonists. In this context, Ca2+ regulatory mechanisms in airway smooth muscle and changes in these regulatory mechanisms encompass a major component of airway hyperresponsiveness. Although dynamic Ca2+ regulation is complex, phospholipase C/inositol tris-phosphate (PLC/IP3) and CD38-cyclic ADP-ribose (CD38/cADPR) are two major pathways mediating agonist-induced Ca2+ regulation in airway smooth muscle. Altered CD38 expression or enhanced cyclic ADP-ribosyl cyclase activity associated with CD38 contributes to human pathologies such as asthma, neoplasia, and neuroimmune diseases. This review is focused on investigations on the role of CD38-cyclic ADP-ribose signaling in airway smooth muscle in the context of transcriptional and posttranscriptional regulation of CD38 expression. The specific roles of transcription factors NF-kB and AP-1 in the transcriptional regulation of CD38 expression and of miRNAs miR-140-3p and miR-708 in the posttranscriptional regulation and the underlying mechanisms of such regulation are discussed
Robustness of Massively Parallel Sequencing Platforms
The improvements in high throughput sequencing technologies (HTS) made clinical sequencing projects such as ClinSeq and Genomics England feasible. Although there are significant improvements in accuracy and reproducibility of HTS based analyses, the usability of these types of data for diagnostic and prognostic applications necessitates a near perfect data generation. To assess the usability of a widely used HTS platform for accurate and reproducible clinical applications in terms of robustness, we generated whole genome shotgun (WGS) sequence data from the genomes of two human individuals in two different genome sequencing centers. After analyzing the data to characterize SNPs and indels using the same tools (BWA, SAMtools, and GATK), we observed significant number of discrepancies in the call sets. As expected, the most of the disagreements between the call sets were found within genomic regions containing common repeats and segmental duplications, albeit only a small fraction of the discordant variants were within the exons and other functionally relevant regions such as promoters. We conclude that although HTS platforms are sufficiently powerful for providing data for first-pass clinical tests, the variant predictions still need to be confirmed using orthogonal methods before using in clinical applications
Repeated games for eikonal equations, integral curvature flows and non-linear parabolic integro-differential equations
The main purpose of this paper is to approximate several non-local evolution
equations by zero-sum repeated games in the spirit of the previous works of
Kohn and the second author (2006 and 2009): general fully non-linear parabolic
integro-differential equations on the one hand, and the integral curvature flow
of an interface (Imbert, 2008) on the other hand. In order to do so, we start
by constructing such a game for eikonal equations whose speed has a
non-constant sign. This provides a (discrete) deterministic control
interpretation of these evolution equations. In all our games, two players
choose positions successively, and their final payoff is determined by their
positions and additional parameters of choice. Because of the non-locality of
the problems approximated, by contrast with local problems, their choices have
to "collect" information far from their current position. For integral
curvature flows, players choose hypersurfaces in the whole space and positions
on these hypersurfaces. For parabolic integro-differential equations, players
choose smooth functions on the whole space
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