704 research outputs found

    Fair value accounting and financial stability.

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    Market prices give timely signals that can aid decision making. However, in the presence of distorted incentives and illiquid markets, there are other less benign effects that inject artifi cial volatility to prices that distorts real decisions. In a world of marking-to-market, asset price changes show up immediately on the balance sheets of financial intermediaries and elicit responses from them. Banks and other intermediaries have always responded to changes in economic environment, but marking-to-market sharpens and synchronises their responses, adding impetus to the feedback effects in financial markets. For junior assets trading in liquid markets (such as traded stocks), marking-to-market is superior to historical cost in terms of the trade-offs. But for senior, long-lived and illiquid assets and liabilities (such as bank loans and insurance liabilities), the harm caused by distortions can outweigh the benefi ts. We review the competing effects and weigh the arguments.

    Influence of quantum confinement on the ferromagnetism of (Ga,Mn)As diluted magnetic semiconductor

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    We investigate the effect of quantum confinement on the ferromagnetism of diluted magnetic semiconductor Ga1x_{1-x}Mnx_xAs using a combination of tight-binding and density functional methods. We observe strong majority-spin Mn dd-As pp hybridization, as well as half metallic behavior, down to sizes as small as 20 \AA in diameter. Below this critical size, the doped holes are self-trapped by the Mn-sites, signalling both valence and electronic transitions. Our results imply that magnetically doped III-V nanoparticles will provide a medium for manipulating the electronic structure of dilute magnetic semiconductors while conserving the ferromagnetic properties and even enhancing it in certain size regime.Comment: 4 pages, 3 figure

    A general model for sample size determination for collecting germplasm

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    The paper develops a general model for determining the minimum sample size for collecting germplasm for genetic conservation with an overall objective of retaining at least one copy of each allele with preassigned probability. It considers sampling from a large heterogeneous 2 k-ploid population under a broad range of mating systems leading to a general formula applicable to a fairly large number of populations. It is found that the sample size decreases as ploidy levels increase, but increases with the increase in inbreeding. Under exclusive selfing the sample size is the same, irrespective of the ploidy level, when other parameters are held constant. Minimum sample sizes obtained for diploids by this general formula agree with those already reported by earlier workers. The model confirms the conservative characteristics of genetic variability of polysomic inheritance under chromosomal segregation

    PRS9 MANAGED-CARE BUDGET IMPACT OF OMALIZUMAB FOR MODERATE TO SEVERE PERSISTENT ASTHMA

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    Scenario Based Run-time Switching for Adaptive CNN-based Applications at the Edge

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    Convolutional Neural Networks (CNNs) are biologically inspired computational models that are at the heart of many modern computer vision and natural language processing applications. Some of the CNN-based applications are executed on mobile and embedded devices. Execution of CNNs on such devices places numerous demands on the CNNs, such as high accuracy, high throughput, low memory cost, and low energy consumption. These requirements are very difficult to satisfy at the same time, so CNN execution at the edge typically involves trade-offs (e.g., high CNN throughput is achieved at the cost of decreased CNN accuracy). In existing methodologies, such trade-offs are either chosen once and remain unchanged during a CNN-based application execution, or are adapted to the properties of the CNN input data. However, the application needs can also be significantly affected by the changes in the application environment, such as a change of the battery level in the edge device. Thus, CNN-based applications need a mechanism that allows to dynamically adapt their characteristics to the changes in the application environment at run-time. Therefore, in this article, we propose a scenario-based run-time switching (SBRS) methodology, that implements such a mechanism

    Research Notes : United States : Evaluation of soybean germplasm for stress tolerance and biological efficiency : To evaluate soybean germplasm for biological efficiency in - Nitrogen Fixation

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    Twenty commercial soybean cultivars from maturity groups IV through VIII were screened for nitrogen-fixation in a growth chamber using Rhizobium strains 3IlB 6,122 and combination of 6 and 122. The data on nodule number, nodule weight, shoot fresh weight, shoot dry weight, and acetylene reduction were recorded. Among twenty cultivars, \u27Lee 74\u27 (MG IV), \u27Bay\u27 (MG V), and \u27Essex\u27 (MG V) were identified as high N-fixers, based on more nodules and high acetylene reduction

    Sample size for collecting germplasms - a polyploid model with mixed mating system

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    The present paper discusses a general expression for determining the minimum sample size (plants) for a given number of seeds or vice versa for capturing multiple allelic diversity. The model considers sampling from a large 2 k-ploid population under a broad range of mating systems. Numerous expressions/results developed for germplasm collection/regeneration for diploid populations by earlier workers can be directly deduced from our general expression by assigning appropriate values of the corresponding parameters. A seed factor which influences the plant sample size has also been isolated to aid the collectors in selecting the appropriate combination of number of plants and seeds per plant. When genotypic multiplicity of seeds is taken into consideration, a sample size of even less than 172 plants can conserve diversity of 20 alleles from 50,000 polymorphic loci with a very large probability of conservation (0.9999) in most of the cases

    Dual-color emitting quantum-dot-quantum-well CdSe-ZnS heteronanocrystals hybridized on InGaN/GaN light emitting diodes for high-quality white light generation

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    Cataloged from PDF version of article.We report white light generation by hybridizing green-red emitting (CdSe)ZnS/CdSe (core)shell/shell quantum-dot-quantum-well heteronanocrystals on blue InGaN/GaN light emitting diodes with the photometric properties of tristimulus coordinates (x,y)=(0.36,0.30), luminous efficacy of optical radiation LE=278 lm/W, correlated color temperature CCT=3929 K, and color-rendering index CRI=75.1. We present the photometric analysis and the quantum mechanical design of these dual-color emitting heteronanocrystals synthesized to achieve high-quality white light when hybridized on light emitting diodes. Using such multicolor emitting heteronanocrystals facilitates simple device implementation while providing good photometric properties. (C) 2008 American Institute of Physics

    Measurement properties of the Flu-Like Symptom Index from the Hepatitis Physical Symptom Severity Diary

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    Purpose Chronic Hepatitis C (CHC) Virus infection is a serious health issue in the US. Standard treatment involves peginterferon alpha and ribavirin, often associated with adverse side effects including flu-like symptoms. These adverse effects are common reasons for the discontinuation of treatment and therefore represent a major obstacle in the effective treatment of CHC. Methods The Hepatitis Physical Symptom Severity Diary, a newly developed patient-reported outcome mea-sure for assessing physical symptoms in CHC patients, was recently developed. It contains four questions addressing flu-like symptoms [the Flu-Like Symptom Index (FLSI)]. Measurement properties of the FLSI in CHC patients were assessed using data from two randomized clinical trials. Results Exploratory factor analysis using data from baseline and the last visit while on treatment supported a single-factor solution for the FLSI. Internal reliability and test–retest reliability are acceptable (Cronbach’s alpha range 0.73–0.81; intraclass correlation coefficient range 0.85–0.97), and correspondence to several similar con-structs was acceptable. The FLSI score was higher among those with investigator-reported flu-like symptoms (mean = 4.1) versus those without (1.4), although not statistically significant (p = 0.12). Responsiveness of the FLSI was moderate, as measured by standardized effect sizes and response means, and the minimum important difference (MID) was estimated at 2.5–3.0 points. Conclusions While additional research should be con-ducted to evaluate validity with more closely related con-structs and to utilize anchor-based methods for estimating the MID, data suggest that the FLSI has acceptable mea-surement properties and can be an effective tool in assessing flu-like symptoms in CHC patients
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