14 research outputs found
Investigation of the Best Approach for Assessing Human Exposure to Poly- and Perfluoroalkyl Substances through Indoor Air
Per- and polyfluoroalkyl substances
(PFASs), including fluorotelomer
alcohols (FTOHs), perfluoroalkyl sulfonamidoethanols (FOSEs), and
perfluoroalkyl sulfonamides (FOSAs), were assessed in 61 residential
indoor air and 15 personal air samples collected in Oslo area, Norway.
FTOHs were detected in all samples, and the median concentrations
in residential indoor air were 2970, 10400, and 3120 pg m<sup>â3</sup> for 6:2, 8:2, and 10:2 FTOH, respectively. This is similar to or
higher than previously reported in studies from the same geographical
area and worldwide. FOSEs and FOSAs were detected in 49â70%
and 7â13% of the residential indoor air samples, respectively.
The median FTOH concentrations observed in personal air were 1970,
7170, and 1590 pg m<sup>â3</sup> for 6:2, 8:2, and 10:2 FTOH,
respectively, which is 30 to 50% lower than the median concentrations
in residential indoor air. No FOSEs or FOSAs were detected above the
method detection limit (MDL) in the personal air samples. Intakes
of perfluorohexanoate (PFHxA), perfluoroheptanoate (PFHpA), perfluorooctanoate
(PFOA), perfluorononanoate (PFNA), perfluorodecanoate (PFDA), perfluoroundecanoate
(PFUnDA), and perfluorooctyl sulfonate (PFOS) through inhalation and
biotransformation of PFAS precursors in air were estimated. Median
intakes of 1.7, 0.17, 5.7, 0.57, 1.8, 0.18, and 2.3 pg kg bw<sup>â1</sup> day<sup>â1</sup> were obtained in residential indoor air,
while 1.0, 0.10, 3.3, 0.33, 0.88, and 0.09 pg kg bw<sup>â1</sup> day<sup>â1</sup> were found in personal air for PFHxA, PFHpA,
PFOA, PFNA, PFDA, PFUnDA, and PFOS, respectively. The median PFOA
intakes from residential indoor air (5.7 pg kg bw<sup>â1</sup> day<sup>â1</sup>) and personal air (3.3 pg kg bw<sup>â1</sup> day<sup>â1</sup>) were both around 5 orders of magnitude
lower than the tolerable daily intake (TDI) reported by the European
Food Safety Authority (EFSA)