Biohazards associated with materials used in prosthodontics

Dental materials for permanent restorations are manufactured with the intent to be stable and insoluble, but they do not fully achieve this goal. The amount of dissolved components is small and their detection sometimes requires sophisticated analytical equipment. The minute amounts of components that leach out of permanent dental restorative materials are most unlikely to cause toxic reactions, locally or systemically. Reliable research information using robust methodology is thus needed to clarify the various safety issues and frequency of adverse reactions in general dentistry,including prosthodontic treatment.Key words: Adverse effects, biocompatibility, formaldehyde, nanoparticles, polymeric restorative material

Gender norms and relations in an agricultural watershed project in the Parasai-Sindh Watershed, Jhansi/India

Agricultural watershed projects require intertwined technical and social interventions, and accompanying research should aim at blending technical and social sciences (Douthwaite et al. 2001). CGIAR research programs have been designed by centers and partners with such an approach since their first phase from 2010 to 2016; and also in their second phase, 2017 to 2022, this interdisciplinary approach represents their conditions of existence. As many studies have demonstrated, the success of agricultural intervention projects depends on the degree of participatory approach and gendersensitivity in each project stage: planning, design, implementation and monitoring (Leder et al. 2017; Quisumbing et al. 2014). Hence, any intervention project should develop mechanisms trying to avoid the reproduction of gender relations and the exclusion of diverse local knowledge at the community level. Instead, a holistic approach to empower communities with its diverse members should be developed and adjusted continuously. While “participatory” has become a buzzword, it is necessary to demystify respective project stakeholders’ assumptions. As Cleaver (1998: 293) argues, “sectorial bias, instrumental approaches to participation, and an inadequate understanding of social context (...) detract from a truly gendered understanding of water resource management“. Hence it is the role of any intervening organization to understand diverse water needs, and to identify who accesses water and who controls water access. Women are traditionally associated with the domestic use of water, while men are linked to the productive uses of water, whereas several studies have found this division inadequate and far more complex, particularly in the context of primarily male out-migration and the so-called feminization of agriculture. In their study on agrobiodiversity management in Nepals Himalaya, Bhattarai et al. (2015: 129) found that women’s lack of power can be “reinforced by the development organizations’ acceptance of established gender roles that privileges men with new products associated with cash”

SERUM FERRITIN AND HbA1c LEVELS IN TYPE 2 DIABETES MELLITUS

Introduction: Complications due to diabetes are a major cause of disability, reduced quality of life and death. Recent studies have emphasized the role of serum ferritin in insulin resistance and the incidence of diabetes mellitus. However, the role of ferritin as a marker of iron overload in pancreatic damage and peripheral insulin resistance or its role as an inflammatory marker is not clear. The aim of this study is to establish a correlation between serum ferritin, FBS and HbA1c in type 2 diabetes mellitus and to evaluate the role of serum ferritin on the glycemic status in type 2 diabetes mellitus. Methods: This was a cross- sectional study of 100 cases, visiting medical outpatient department of a tertiary care teaching hospital. Diabetic patients were compared with age and sex matched normal healthy controls. Effect of serum ferritin on glycemic status, gender and age was noted. Results: Statistically significant increase of FPG, HbA1C and serum ferritin levels were observed in type 2 diabetes mellitus group than controls in both females and males while there was no statistically significant difference of hemoglobin between diabetic group and controls in females and males. There was a high (r= 0.62, r= 0.66) positive correlation between SF and HbA1c of females and males respectively in diabetic group P-value=< 0.01. Conclusion: Higher positive correlation of serum ferritin with HbA1c shows that hyperglycemia affects ferritin levels possibly due to inflammation or oxidative stress or a combination of the two. KEYWORDS: Type 2 diabetes mellitus; Glycosylated haemoglobin; Ferritin

SERUM FERRITIN AND HbA1c LEVELS IN TYPE 2 DIABETES MELLITUS

Introduction: Complications due to diabetes are a major cause of disability, reduced quality of life and death. Recent studies have emphasized the role of serum ferritin in insulin resistance and the incidence of diabetes mellitus. However, the role of ferritin as a marker of iron overload in pancreatic damage and peripheral insulin resistance or its role as an inflammatory marker is not clear. The aim of this study is to establish a correlation between serum ferritin, FBS and HbA1c in type 2 diabetes mellitus and to evaluate the role of serum ferritin on the glycemic status in type 2 diabetes mellitus. Methods: This was a cross- sectional study of 100 cases, visiting medical outpatient department of a tertiary care teaching hospital. Diabetic patients were compared with age and sex matched normal healthy controls. Effect of serum ferritin on glycemic status, gender and age was noted. Results: Statistically significant increase of FPG, HbA1C and serum ferritin levels were observed in type 2 diabetes mellitus group than controls in both females and males while there was no statistically significant difference of hemoglobin between diabetic group and controls in females and males. There was a high (r= 0.62, r= 0.66) positive correlation between SF and HbA1c of females and males respectively in diabetic group P-value=< 0.01. Conclusion: Higher positive correlation of serum ferritin with HbA1c shows that hyperglycemia affects ferritin levels possibly due to inflammation or oxidative stress or a combination of the two. KEYWORDS: Type 2 diabetes mellitus; Glycosylated haemoglobin; Ferritin

Microwave-Assisted Alkali Delignification Coupled with Non-Ionic Surfactant Effect on the Fermentable Sugar Yield from Agricultural Residues of Cassava

Cassava stem, leaves and peel are agricultural residues generated as waste biomass during the cultivation and processing of cassava. The potential of these biomasses as feedstock for ethanol production depends on the effective deconstruction via pretreatment and saccharification. The effect of alkaline hydrogen peroxide (AHP) treatment on microwave (MW)-irradiated or steam-exposed aqueous slurry was compared with MW-irradiation (300 W) of alkali slurry in delignifying the biomass and degrading the polysaccharides. Cellulose was degraded to a higher extent than hemicellulose in the AHP treatments. The steam-exposed and AHP pretreated residues on saccharification with Cellic (Cellulase complex) alone or Cellic along with Tween 20 resulted in high conversion of carbohydrate to reducing sugars (RS) in leaves (64-70%) and peel (74- 78%), with slightly lower conversion in stem. MW-irradiation of alkali slurry (5 min.) followed by Tween 20 supplemented saccharification was a better strategy degrading cellulose and hemicellulose to very high extent. Tween 20 supplementation was beneficial in enhancing the RS release from the biomasses even when Cellic dosage was halved. Ultrastructural studies indicated the disappearance of starch granules from stem and peel samples after MW-irradiation and saccharification, while fragmented cellulose fibers were visible in leaf samples. The study showed that MW-assisted alkali pretreatment followed by saccharification with Cellic in presence of Tween 20 was very effective in releasing maximum sugars from these biomasses

Prevalence of Malnutrition in Adolescent Girls: A Cross-Sectional Study in the Tribal Regions of Telangana

Malnutrition continues to be one of India's major human development challenge. Despite enormous economic progress achieved in the past two to three decades, malnutrition rates continue to be high especially among children and adolescents in both urban and rural India. The shining India is in shade on these important human development indicators. Adolescents in India especially those residing in tribal regions are at high nutritional risk and face health issues such as anemia and chronic disorders. This paper investigates the prevalence, causes and socio-economic-cultural determinants of malnutrition among 11 to 18 years old adolescent tribal girls from the districts of Adilabad, Komaram-Bheem Asifabad and Mancherial in Telangana state. The cross sectional survey collected data in the year 2017 on socio-economic, demographic, diet and anthropometric indicators from 695 tribal adolescent girls out of 2542 tribal households. The analysis of the anthropometric data reveals that about 67 percent of adolescent girls are undernourished having a BMI of less than 18.5. The results revealed that stunting and thinness was highly prevalent among the tribal adolescent girls. Overweight or obesity is not of particular concern in the studied tribal adolescent girls. These adolescents also lack basic awareness about food, nutrition, health and overall wellbeing. The paper ultimately determines the need for a concerted combination of policies and programs specifically aimed at adolescents in the tribal regions addressing poverty, education, nutrition literacy, empowerment to challenge the existing cultural norms related to food consumption and access to diverse diets both in terms of quantity and quality

Line coordination in a rapid change, high volume environment

Thesis (M.B.A.)--Massachusetts Institute of Technology, Sloan School of Management; and, (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering; in conjunction with the Leaders for Manufacturing Program at MIT, 2004.Includes bibliographical references (p. 89-90).Raytheon - Integrated Defense Systems (IDS) manufactures surface radars. In the past, Raytheon's Andover plant was primarily a systems integration facility receiving subassemblies from other sources to assemble the radars. Hence for a long time, building surface radars in low volume had been the norm. However, since the last few years the plant also has been producing some of these subassemblies in high volume. Due to this, the facility had to transition from a predominantly low volume manufacturing environment to one that includes high volume assembly lines. This thesis examines the challenges that arose due to the transition from a low volume to a high volume manufacturing environment. One of the major problems examined was throughput variability on a high volume assembly line. It has been determined that throughput variability can be reduced by achieving line coordination; i.e. "balance in the flow across the assembly line". This thesis emphasizes the importance of effective execution of the production plan to reduce throughput variability. It focuses on three key areas that needed improvement: Culture, Manufacturing Practices, and Business Systems. The thesis includes improvements implemented to achieve line coordination.by Padmaja S. Vanka.S.M.M.B.A

Evaluation of efficacy and safety of terbinafine and itraconazole in superficial mycoses: a prospective, randomized, controlled and cost-effective analysis study

Background: Superficial mycoses are common worldwide. Dermatophytic infections can greatly affect quality of life. Several newer antimycotic agents, have been reported effective and safe. Hence this study was planned to analyse effectiveness as well as cost effectiveness of these treatments.Methods: It were a prospective, randomized, parallel, open label, comparative study. Fifty patients were included in the study and divided into 2 groups. They were randomized to receive either oral terbinafine 250 mg or itraconazole 100 mg once daily for 4 weeks. Scaling, erythema and pruritus were rated as clinical score 0 to 3: 0 - absent, 1 - mild, 2 - moderate, and 3 - severe for the above three target symptoms. Total symptom score was assessed. Pruritus was also graded on visual analogue scale (VAS). Mycological cure was assessed by skin scraping with KOH mounts and fungal culture. Clinical efficacy scoring and VAS were assessed before the study and at each follow up visit at 2 and 4 weeks. Patients were followed up for another 4 weeks after completion of the treatment.Results: There was highly significant decrease p<000.1 in the mean total symptoms scores in both the study groups from baseline. No significant difference in the mean total symptoms score was observed when compared between groups. ADRs were more in terbinafine group.Conclusions: Both terbinafine and itraconazole are effective and safe against superficial mycoses, but adverse effects are more with terbinafine. Itraconazole was found to be cost effective compared to terbinafine

A comparative study on field performance of micropropagated plants and stem cutting derived plants of S-36 cultivar of Mulberry (Morus indica L.)

Micropropagated and stem cutting derived plants of Mulberry (Morus indica L. cv. S-36) were transferred to the similar field conditions. A comparative study was conducted based on morphological parameters and growth characteristics for three consecutive years.  The results demonstrated that micropropagation gave rise to superior clonal populations with respect to number of branches/plant and leaf yield/plant that will be suitable for the mass production of plants.  Thus in vitro grown plants did not exhibit any significant quantitative variation as compared to the conventionally grown plants, indicating the varietal multiplication to be of true-to-type

Correlation of serum lithium levels and thyroid function tests in subjects of bipolar affective disorder: a prospective hospital-based study

Background: Lithium is used in the prophylaxis of long-term therapy of bipolar affective disorder (BPAD) as a mood-stabilizing agent. Thyroid function abnormality is very commonly seen adverse effect, more common in females than males. This study aimed to correlate lithium levels and thyroid function abnormalities associated with it.Methods: Evaluation of medical records of 150 patients in Father Muller Medical College with BPAD, who were treated for 6 months with lithium, carried out from February, 12 2014 to July, 20 2014. Serum lithium levels done by ion selective electrode method in ilyte analyzer and thyroid function test (TFT) by electrochemiluminescence. Data are analyzed by Karl Pearson correlation coefficient.Results: Correlation of lithium levels and TFT in BPAD patients according to Karl Pearson correlation coefficient was negative with significant p&lt;0.002. Among 150 enrolled candidates, 52 (34.67%) were females and 98 (65.4%) were males, 4% (6) patients (3 males and 3 females) had thyroid stimulating hormone (TSH) value &lt;0.27 with an average lithium value of 1.35 mEq/L, 6% (9) patients (5 males and 4 females) had TSH value &gt;4.2 with an average lithium levels of 0.44 mEq/L and 90% of the patients with an average lithium levels 0.66 mEq/L had no thyroid function abnormalities.Conclusions: As already known, Lithium is a drug of narrow therapeutic index and females are more prone for thyroid function abnormalities. Appropriate monitoring of serum lithium levels will aid in necessary dose adjustment and ensure proper utilization of drug