781 research outputs found

    Chaotic scattering with direct processes: A generalization of Poisson's kernel for non-unitary scattering matrices

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    The problem of chaotic scattering in presence of direct processes or prompt responses is mapped via a transformation to the case of scattering in absence of such processes for non-unitary scattering matrices, \tilde S. In the absence of prompt responses, \tilde S is uniformly distributed according to its invariant measure in the space of \tilde S matrices with zero average, < \tilde S > =0. In the presence of direct processes, the distribution of \tilde S is non-uniform and it is characterized by the average (\neq 0). In contrast to the case of unitary matrices S, where the invariant measures of S for chaotic scattering with and without direct processes are related through the well known Poisson kernel, here we show that for non-unitary scattering matrices the invariant measures are related by the Poisson kernel squared. Our results are relevant to situations where flux conservation is not satisfied. For example, transport experiments in chaotic systems, where gains or losses are present, like microwave chaotic cavities or graphs, and acoustic or elastic resonators.Comment: Added two appendices and references. Corrected typo

    Combined use of vacuum assisted device and dermal monolayer substitutes

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    Artículo previamente publicado en Cirugia Plástica Iberolatinoamericana Vol. 36 - Nº 4. 2010 / Pag. 321-326El método de elección para la cobertura de algunos defectos cutáneos es el autoinjerto de piel parcial; sin embargo, sufre retracciones que pueden adquirir gran relevancia sobre áreas especiales. Diferentes autores han intentado evitar estos déficits funcionales mediante la interposición de matrices de regeneración dérmica monocapa e injerto en un solo tiempo quirúrgico. Diseñamos un estudio para comparar la tasa de integración de los injertos sobre una matriz monocapa con y sin la aplicación de terapia de vacío tipo VAC® sobre ellos. Se aleatorizaron 20 pacientes con defectos cutáneos sobre áreas especiales en 2 grupos. Recogimos los datos epidemiológicos y la etiología del defecto (quemadura aguda, secuelas de quemadura o defectos secundarios a extracción de colgajo fasciocutáneo). En 10 casos (Grupo I) se aplicó matriz dérmica monocapa Matriderm ® más un injerto cutáneo de piel parcial, realizando un cambio de vendaje a los 7 días y luego cada 3- 4 días hasta su estabilización. En otros 10 pacientes (Grupo II), tras realizar el mismo protocolo quirúrgico se aplicó VAC ® durante una semana y se cambió hasta la estabilización del injerto. La evaluación del prendimiento del injerto y su estabilidad la realizó un observador ciego. Se recogieron todas las complicaciones surgidas en el postoperatorio hasta 3 meses después de la estabilidad del injerto. Comprobamos la homogeneidad de ambos grupos para las variables epidemiológicas de los pacientes, así como para la etiología de los defectos. La media de tiempo hasta el prendimiento fue de 17,6 ± 8 días, de forma global con una tasa de complicaciones del 20%. Al estratificar en 2 grupos encontramos que las diferencias en la tasa de complicaciones no eran estadísticamente significativas. El tiempo hasta el prendimiento era de 21,4 ± 9 días en el grupo I, frente a 13,9 ± 4 días en el grupo II. Estas diferencias sí eran estadísticamente significativas. Como conclusión, la aplicación de matrices de regeneración dérmica monocapa es segura, con una tasa de prendimiento de los injertos sobre ella del 85%. El uso del VAC ® sobre las láminas monocapa de dermis sintética acorta el tiempo de integración de las mismas y el prendimiento de los injertos sobre ellas, con una tasa de complicaciones similarSplit thickness autografts are the gold standard for wound coverage. However, scars and retractions are frequent after skin grafts, and would be severe over special regions. Different authors avoid these complications using a dermal substitute interposed between the wound and the skin graft in the first surgical time. A prospective study was designed to evaluate the split thickness skin graft uptake time over a monolayer matrix, with and without a vacuum assisted therapy device (VAC®). Twenty patients with a full thickness wound over a special region were randomized between 2 groups. Epidemiological data and wound etiology (acute burn, burn sequelae or donor site after a fasciocutaneous flap raised) were collected. Matriderm ® (mono layer dermal substitute) and a split thickness skin graft was applied over 10 cases (Group I). The dressing was changed after 7 days, and every 3-4 days until the skin graft was uptake and stable. Another 10 cases were treated with the same surgical strategy (Group II). After surgery, a vacuum assisted therapy device (VAC®) was applied until the graft was uptake. The skin graft evaluation was done by a blind observer. All complications were reported until 3 months after the skin graft was stable. The homogeneity between groups was assessed. Averaged uptake time was 17, 6 ± 8 days, and the total complication rate was 20%. Statistically differences were not found between the 2 groups for the complication rate. The uptake time was 21,4 ± 9 days in the Group I and 13,9 ± 4 days in the Group II. These differences was statically significative. As a conclusion, the use of monolayer dermal substitutes is safe, with skin graft uptake rate of 85%. Time for skin graft uptake over a monolayer dermal matrix is shorter using a VAC ® device over the skin graft, with similar complication rat

    Momento Económico (13)

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    En este número Temas de hoy, El desprendimiento de las paraestatales, 21 México: La coyuntura del susector paraestatal, Ramón Martínez Escamilla, 3/ Imperialismo y petróleo: una evocación de la leyenda de Transilvania, Isaac Palacios Solano, 6/ El mercado petrolero mundial y las perspectivas de recuperación de la economía mexicana, Raúl Gonzlllez Soriano, 9/ Presupuesto del D.F. para 1985: 6% menos que en 1984, Alejandro Méndez Rodriguez, 11/ El impacto de la política urbana del régimen actual en los sectores populares, Bernardo Navano y Jum Manuel Ramírez S., 1

    Molecular analysis of lungs from pigs immunized with a mutant transferrin binding protein B-based vaccine and challenged with Haemophilus parasuis

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    38 p.The molecular analysis of pigs vaccinated with a mutant transferrin-binding protein B (Y167A) from Haemophilus parasuis was compared with that performed for unvaccinated challenged (UNCH) and unvaccinated unchallenged (UNUN) pigs. Microarray analysis revealed that UNCH group showed the most distinct expression profile for immune response genes, mainly for those genes involved in inflammation or immune cell trafficking. This fact was confirmed by real-time PCR, in which the greatest level of differential expression from this group were CD14, CD163, IL-8 and IL-12. In Y167A group, overexpressed genes included MAP3K8, CD14, IL-12 and CD163. Proteomics revealed that collagen -1 and peroxiredoxins 2 and 6 were overexpressed in Y167A pigs. Our study reveals new data on genes and proteins involved in H. parasuis infection and several candidates of resistance to infection that are induced by Y167A vaccine. The expression of proinflammatory molecules from Y176A pigs is similar to their expression in UNUN pigsS

    Anatomical dissection of the mimic facial musculature: iconographic review as a support to the complementary treatments in facial rejuvenation

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    A la hora de valorar las múltiples técnicas empleadas en el rejuvenecimiento facial y centrándonos de manera particular en aquellos procedimientos mínimamente invasivos complementarios a las intervenciones habituales en Cirugía Plástica-Estética, cobra especial relevancia el conocimiento exhaustivo de las estructuras musculares implicadas en la mímica facial. A tal efecto, se ha realizado un estudio anatómico en cadáveres frescos, en los que se han disecado las principales estructuras referidas. Se presenta un resumen iconográfico de los músculos faciales implicados, haciendo hincapié en su anatomía descriptiva y funcional, así como un recuerdo de las principales áreas problemáticas por alguna circunstancia especial (presencia de un nervio sensitivo o motor).To value the multiple technologies involved in facial rejuvenation and focusing in those minimally invasive complementary procedures to the usual Plastic and Aesthetic Surgeries, it´s very important the exhaustive knowledge of the muscular structures involved in the facial movements. To such an effect, an anatomical study has been realized in fresh corpses, dissecting the principal above-mentioned structures. We present an iconographic summary of the facial implied muscles, emphasizing in his descriptive and functional anatomy, as well as a recollection of the principal problematic areas for some special circumstance (presence of a sensory or motor nerv

    Hydrothermal assisted synthesis of iron oxide-based magnetic silica spheres and their performance in magnetophoretic water purification

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    Porous Magnetic Silica (PMS) spheres of about 400 nm diameter were synthesised by one-pot process using the classical Stӧber method combined with hydrothermal treatment. Maghemite nanoparticles (γ-Fe2O3) were used as fillers and cetyltrimethylammonium bromide (CTAB) was used as templating agent. The application of the hydrothermal process (120 °C during 48 h) before the calcination leads to the formation of homogeneous and narrow size distribution PMS spheres. X-ray diffraction patterns (XRD), Infrared measurements (FTIR) and Transmission Electron microscopy (TEM) methods were used to determine the composition and morphology of the obtained PMS spheres. The results show a homogeneous distribution of the γ-Fe2O3 nanoparticles in the silica matrix with a “hollow-like” morphology. Magnetophoresis measurements at 60 T m−1 show a total separation time of the PMS spheres suspension of about 16 min. By using this synthesis method, the limitation of the formation of silica spheres without incorporation of magnetic nanoparticles is overcome. These achievements make this procedure interesting for industrial up scaling. The obtained PMS spheres were evaluated as adsorbents for Ni2+ in aqueous solution. Their adsorption capacity was compared with the adsorption capacity of magnetic silica spheres obtained without hydrothermal treatment before calcination process. PMS spheres show an increase of the adsorption capacity of about 15% of the initial dissolution of Ni2+ without the need to functionalize the silica surface.Fundação para a Ciência e a Tecnologia (FCT

    Fasciola hepatica induces eosinophil apoptosis in the migratory and biliary stages of infection in sheep

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    The aim of the present work was to evaluate the number of apoptotic eosinophils in the livers of sheep experimentally infected with Fasciola hepatica during the migratory and biliary stages of infection. Four groups (n = 5) of sheep were used; groups 1–3 were orally infected with 200 metacercariae (mc) and sacrificed at 8 and 28 days post-infection (dpi), and 17 weeks post-infection (wpi), respectively. Group 4 was used as an uninfected control. Apoptosis was detected using immunohistochemistry with a polyclonal antibody against anti-active caspase-3, and transmission electron microscopy (TEM). Eosinophils were identified using the Hansel stain in serial sections for caspase-3, and by ultrastructural features using TEM. At 8 and 28 dpi, numerous caspase-3+ eosinophils were mainly found at the periphery of acute hepatic necrotic foci. The percentage of caspase -3+ apoptotic eosinophils in the periphery of necrotic foci was high (46.1–53.9) at 8 and 28 dpi, respectively, and decreased in granulomas found at 28 dpi (6%). Transmission electron microscopy confirmed the presence of apoptotic eosinophils in hepatic lesions at 8 and 28 dpi. At 17 wpi, apoptotic eosinophils were detected in the infiltrate surrounding some enlarged bile ducts containing adult flukes. This is the first report of apoptosis induced by F. hepatica in sheep and the first study reporting apoptosis in eosinophils in hepatic inflammatory infiltrates in vivo. The high number of apoptotic eosinophils in acute necrotic tracts during the migratory and biliary stages of infection suggests that eosinophil apoptosis may play a role in F. hepatica survival during different stages of infection.This work was supported by EU grants (FPVII-265862-PARAVAC, H2020-635408-PARAGONE) and the Spanish Ministry of Science grant AGL2009-08726. TEM studies were carried out by the Central Services for Research of the University of Córdoba (SCAI)Veterinari

    Postoperative endometrial cancer treatments with electronic brachytherapy source

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    Purpose This study is a dosimetric and acute toxicity comparison of endometrial cancer patients treated with either Axxent (Xoft, Inc., San José, CA, USA) electronic and interstitial brachytherapy versus interstitial high dose rate brachytherapy (HDRBT). Materials and Methods Between 2015 and 2017, 94 patients with postoperative endometrial cancer were treated in our centre with the Axxent electronic brachytherapy (eBT) system. The V 150 and V 200 are evaluated prospectively for each plan. The mean age of patients was 65.9 years (age range 33-84 years), with different tumour staging. Of the 94 patients, 37 received exclusive adjuvant brachytherapy (25 Gy in five sessions); the remaining patients received external beam radiotherapy (EBRT) with a regimen of 23 sessions of 2 Gy each to the entire pelvis, followed by eBT (15 Gy in three sessions). Additionally, the absorbed doses received by the organs at risk (OAR), urinary bladder, rectum and sigmoid colon were compared with HDRBT plans, evaluating D 2cc, V 50% and V 35%. Median follow-up was done for each of the 94 patients to assess the toxicity of the treatment: vaginal mucosa toxicity, rectal and urinary toxicity; and results are presented for acute toxicity, toxicity at 1 month after the end of treatment and follow-up after 12 months for a portion of patients according to the Radiation Therapy Oncology Group (RTOG) toxicity criteria. Results The doses in OAR for eBT plans were lower than that for HDRBT plans, both Ir-192 and Co-60 plans, whose doses were similar. The dose in bladder with eBT was 63.8% of the prescribed dose for D 2cc versus 70.1% for HDRBT Ir-192, for V 50% was 7.2% versus 12.7% and for V 35% was 15.2% versus 28.2%. In rectum the D 2cc was 61.2% versus 68.4%, for V 50% was 7.9% versus 14.3% and for V 35% was 16.7% versus 32%. Results demonstrated lower doses to OAR in all eBT plans. Acute toxicity in eBT was very low in cases of mucositis, with only one case of toxicity greater than grade 1, rectal toxicity and urinary toxicity; results at 1 month are equally good, toxicity symptoms disappeared and no relapses have occurred to date. Conclusions The results of treatment with the Axxent eBT unit for 94 patients are very good, as no recurrence has been observed and the toxicity of the treatment is very low. The increase in V 150 and V 200 has not produced an increase in vaginal mucosa toxicity, and the doses in the OAR are lower than in the plans implemented for HDRBT with Ir-192 or Co-60. eBT is a good alternative to treat endometrial cancer in centres without conventional HDR availability. To date, there are limited published studies reporting on outcomes from patients treated with eBT

    IMPORTANCE OF DIETARY TAURINE AND SELENIUM ON GROWTH AND SURVIVAL OF ATLANTIC BLUEFIN TUNA Thunnus thynnus LARVAE

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    One of the most important bottleneck in the farming of Atlantic bluefin tuna (ABT) is the growth and survival during the larval rearing phase, mainly related with the diet quality. For the last ten years the Spanish Institute of Oceanography (IEO) in Mazarrón (Murcia, SE Spain) has developed a technique for ABT larval rearing and juvenile production. Taurine and selenium are essential water soluble compounds in live preys and inert diets for ABT larvae and juveniles. To know the importance of dietary taurine and selenium on growth and survival of ABT larvae, two experiments have been carried out with different taurine (Exp1) and selenium (Selplex® ) (Exp2) doses added to rotifers enriched with ALGAMAC 3050® . Both experiments were finished at 14 days post hatching. ABT fertilized eggs were collected from captive breeders spawning spontaneously in floating cages in the area. The eggs, transported to the IEO facilities, were quantified, cleaned, selected by buoyancy and distributed randomly in 1400 L fiber cylindrical glass tanks at a density of 10 ABT eggs per liter, whereas prey density was maintained at 5 rotifers per mL. Temperature ranges were: 24.0±0.5ºC and 26.0±0.5ºC for Exp1 and Exp2, respectively. Fig 1 shows the growth results in size for both experiments at 14 dph. Survival in both cases was close to 10% with no significant differences due to the different treatments. The lowest growth in size was observed in larvae fed dose 0 in both experiments Standard length average (mm ± confidence intervals) in Exp1 and Exp2 at 14 dph. Letters indicate statistically significant differences (95%

    Related Factors and Treatment of Postoperative Delirium in Old Adult Patients: An Integrative Review

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    “Postoperative delirium” is defined as delirium occurring in the hospital up to one week after a procedure or before discharge (whichever occurs first) that meets the DSM-5 diagnostic criteria. Objectives: To describe the risk factors related to this pathology and identify effective non-pharmacological forms of treatment. An integrative review of the available literature was performed. The search results considered included all quantitative studies published between 2011 and 2019 in both English and Spanish. A total of 117 studies were selected. Advanced age was identified as the principal risk factor for postoperative delirium. Nursing interventions appear to be the key to preventing or reducing the seriousness of delirium after an anaesthetic episode. The aetiology of postoperative delirium remains unknown, and no treatment exists to eliminate this pathology. The role of nursing staff is fundamental in the prevention, diagnosis, and management of the pathology.S
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