6,315 research outputs found
Multi-Qubit Systems: Highly Entangled States and Entanglement Distribution
A comparison is made of various searching procedures, based upon different
entanglement measures or entanglement indicators, for highly entangled
multi-qubits states. In particular, our present results are compared with those
recently reported by Brown et al. [J. Phys. A: Math. Gen. 38 (2005) 1119]. The
statistical distribution of entanglement values for the aforementioned
multi-qubit systems is also explored.Comment: 24 pages, 3 figure
Quantum teleportation and state sharing using a genuinely entangled six qubit state
The usefulness of the genuinely entangled six qubit state that was recently
introduced by Borras et al. is investigated for the quantum teleportation of an
arbitrary three qubit state and for quantum state sharing (QSTS) of an
arbitrary two qubit state. For QSTS, we explicitly devise two protocols and
construct sixteen orthogonal measurement basis which can lock an arbitrary two
qubit information between two parties.Comment: 6 pages, 7 table
A survey of localization in wireless sensor network
Localization is one of the key techniques in wireless sensor network. The location estimation methods can be classified into target/source localization and node self-localization. In target localization, we mainly introduce the energy-based method. Then we investigate the node self-localization methods. Since the widespread adoption of the wireless sensor network, the localization methods are different in various applications. And there are several challenges in some special scenarios. In this paper, we present a comprehensive survey of these challenges: localization in non-line-of-sight, node selection criteria for localization in energy-constrained network, scheduling the sensor node to optimize the tradeoff between localization performance and energy consumption, cooperative node localization, and localization algorithm in heterogeneous network. Finally, we introduce the evaluation criteria for localization in wireless sensor network
Scholar-activists in an expanding European food sovereignty movement
This article analyzes the roles, relations, and positions of scholar-activists in the European food sovereignty movement. In doing so, we document, make visible and question the political dimensions of researchers' participation in the movement. We argue that scholar-activists are part of the movement, but are distinct from the affected constituencies, put in place to ensure adequate representation of key movement actors. This is because scholar-activists lack a collective identity, have no processes to formulate collective demands, and no mechanisms for inter-researcher and researchers-movement communication. We reflect on whether and how scholar-activists could organize, and discuss possible pathways for a more cohesive and stronger researcher engagement in the movement.</p
Highly entangled multi-qubit states with simple algebraic structure
Recent works by Brown et al and Borras et al have explored numerical
optimisation procedures to search for highly entangled multi-qubit states
according to some computationally tractable entanglement measure. We present an
alternative scheme based upon the idea of searching for states having not only
high entanglement but also simple algebraic structure. We report results for 4,
5, 6, 7 and 8 qubits discovered by this approach, showing that many of such
states do exist. In particular, we find a maximally entangled 6-qubit state
with an algebraic structure simpler than the best results known so far. For the
case of 7, we discover states with high, but not maximum, entanglement and
simple structure, as well as other desirable properties. Some preliminary
results are shown for the case of 8 qubits.Comment: 15 pages, 1 figur
Therapeutic vaccination of woodchucks against chronic woodchuck hepatitis virus infection
BACKGROUND/AIMS:
Therapeutic vaccination is a new approach to treat patients with chronic hepatitis B virus infection. We have used the woodchuck model to examine the efficacy and safety of this approach.
METHODS:
Seven woodchucks chronically infected with woodchuck hepatitis virus were immunized with surface antigen from this virus, purified from plasma, in conjunction with a peptide named FIS (encompassing amino acids 106-118: FISEAIIHVLHSR from sperm whale myoglobin), which is recognized by T helper lymphocytes. As controls, two woodchucks chronically infected with woodchuck hepatitis virus were immunized: one with FIS only and the other with surface antigen only.
RESULTS:
Co-immunization with surface antigen and FIS, but not with FIS or surface antigen alone, induced anti-surface antibodies in 7/7 immunized woodchucks. In the two woodchucks in which the highest titer of anti-surface antibody was elicited, severe liver damage was observed: one died of fulminant hepatitis and the other became seriously ill with hepatic injury and had to be sacrificed.
CONCLUSIONS:
Co-immunization of chronically infected woodchucks with surface antigen and a peptide recognized by T helper cells produces a good anti-surface antibody response. However, this strategy needs to be optimized before its implementation in humans. Although our experiments are not strictly comparable to vaccination of chronically hepatitis B virus-infected patients with recombinant or plasma-derived vaccines, we believe that precautions should be taken to avoid the risk of severe liver injury when immunizing hepatitis B virus carriers
Integrative analysis of extracellular and intracellular bladder cancer cell line proteome with transcriptome: improving coverage and validity of –omics findings
Characterization of disease-associated proteins improves our understanding of
disease pathophysiology. Obtaining a comprehensive coverage of the proteome is
challenging, mainly due to limited statistical power and an inability to
verify hundreds of putative biomarkers. In an effort to address these issues,
we investigated the value of parallel analysis of compartment-specific
proteomes with an assessment of findings by cross-strategy and cross-omics
(proteomics-transcriptomics) agreement. The validity of the individual
datasets and of a “verified” dataset based on cross-strategy/omics agreement
was defined following their comparison with published literature. The
proteomic analysis of the cell extract, Endoplasmic Reticulum/Golgi apparatus
and conditioned medium of T24 vs. its metastatic subclone T24M bladder cancer
cells allowed the identification of 253, 217 and 256 significant changes,
respectively. Integration of these findings with transcriptomics resulted in
253 “verified” proteins based on the agreement of at least 2 strategies. This
approach revealed findings of higher validity, as supported by a higher level
of agreement in the literature data than those of individual datasets. As an
example, the coverage and shortlisting of targets in the IL-8 signalling
pathway are discussed. Collectively, an integrative analysis appears a safer
way to evaluate -omics datasets and ultimately generate models from valid
observations
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