Phylogeny and Power in the IS Domain: A Response to Benbasat and Zmud\u27s Call for Returning to the IT Artifact

We question a call by Benbasat and Zmud (2003) to narrow the focus of information systems research to a set of core properties. We first discuss three limitations of their argument and then offer two alternative viewpoints for analyzing the state of our profession. One viewpoint casts the arguments of Benbasat and Zmud in terms of power in the domain of scholarship. The second viewpoint, based on colonial systems, sees fresh perspectives, discipline newcomers, boundary spanners, and topical outliers as the likely source of the field¡¯s creativity, vitality, and long-term survival. We conclude that the discipline is best served by focusing on supporting diverse and novel research. We proffer neither an alternative research agenda nor a research-appropriate evaluation mechanism since we demonstrate that such restrictive policies hinder both our relevance and potential survival. We suggest some administrative changes for the IS discipline intended to encourage and nurture creativity without sacrificing academic rigor

Zystische Adventitiadegeneration (CAD) als Ursache einer invalidisierenden Claudicatio intermittens

Zusammenfassung: Bei einem 45-jährigen Patienten mit wechselhaften Ischämiebeschwerden und initial limitierter Gehstrecke rechts von höchstens 50m führten die duplexsonographischen und angiographischen Abklärungen zur Verdachtsdiagnose einer zystischen Adventitiadegeneration. Intraoperativ zeigte sich ein zystisch aufgetriebenes Poplitealsegment mit Entleerung von gallertiger Flüssigkeit. Aufgrund der langstreckigen Veränderung erfolgte die Segmentresektion der A.poplitea und Rekonstruktion mittels eines autologen Veneninterponats. Die CAD ist ein seltenes Krankheitsbild, an das gerade bei jungen Patienten ohne systemische Arteriosklerose gedacht werden sollte. Die Therapie ist je nach Fall chirurgisch erhaltend durch Zystenresektion mittels "Exarterektomie" oder gefäßresezierend, insbesondere bei langstreckigen Veränderungen bzw. vollständiger Okklusion mittels Ersatz durch ein Veneninterpona

Lightweight Ceramic Composition of Carbon Silicon Oxygen and Boron

Lightweight, monolithic ceramics resistant to oxidation in air at high temperatures are made by impregnating a porous carbon preform with a sol which contains a mixture of tetraethoxysilane, dimethyldiethoxysilane and trimethyl borate. The sol is gelled and dried on the carbon preform to form a ceramic precursor. The precursor is pyrolyzed in an inert atmosphere to form the ceramic which is made of carbon, silicon, oxygen and boron. The carbon of the preform reacts with the dried gel during the pyrolysis to form a component of the resulting ceramic. The ceramic is of the same size, shape and form as the carbon precursor. Thus, using a porous, fibrous carbon precursor, such as a carbon felt, results in a porous, fibrous ceramic. Ceramics of the invention are useful as lightweight tiles for a reentry spacecraft

Organopolysiloxane Waterproofing Treatment for Porous Ceramics

Rigid and flexible porous ceramics, including thermal insulation of a type used on space vehicles, are waterproofed by a treatment which comprises applying an aqueous solution of an organopolysiloxane water-proofing agent having reactive silanol groups to the surface of the ceramic and then heating the treated ceramic to form a waterproofed ceramic. The organopolysiloxane is formed by the hydrolysis and partial condensation of di- and trialkoxyfunctional alkylalkoxysilanes having 1-10 carbon atom hydrocarbyl groups

Misexpression of a transcriptional repressor candidate provides a molecular mechanism for the suppression of awns by Tipped 1 in wheat.

Awns are bristle-like structures formed at the tip of the lemma on the florets of some cereal grasses. Wild-type wheat is awned, but awnletted and awnless variants have been selected and nowadays all forms are cultivated. In this study, we dissected the genetic control underlying variation of this characteristic feature by association mapping in a large panel of 1110 winter wheat cultivars of worldwide origin. We identified the B1 (Tipped 1) locus on chromosome 5A as the major determinant of awnlessness globally. Using a combination of fine-mapping and expression analysis, we identified a putative C2H2 zinc finger protein with an EAR domain, characteristic of transcriptional repressors, as a likely candidate for Tipped 1. This gene was found to be up-regulated in awnless B1 compared with awned b1 plants, indicating that misexpression of this transcriptional regulator may contribute to the reduction of awn length in B1 plants. Taken together, our study provides an entry point towards a better molecular understanding of the evolution of morphological features in cereals through selection and breeding

Caring for women wanting a vaginal birth after previous caesarean section: A qualitative study of the experiences of midwives and obstetricians

© 2016 Australian College of Midwives Problem One of the greatest contributors to the overall caesarean section rate is elective repeat caesarean section. Background Decisions around mode of birth are often complex for women and influenced by the views of the doctors and midwives who care for and counsel women. Women may be more likely to choose a repeat elective caesarean section (CS) if their health care providers lack skills and confidence in supporting vaginal birth after caesarean section (VBAC). Aim To explore the views and experiences of providers in caring for women considering VBAC, in particular the decision-making processes and the communication of risk and safety to women. Methods A descriptive interpretive method was utilised. Four focus groups with doctors and midwives were conducted. Findings The central themes were: ‘developing trust’, ‘navigating the system’ and ‘optimising support’. The impact of past professional experiences; the critical importance of continuity of carer and positive relationships; the ability to weigh up risks versus benefits; and the language used were all important elements. The role of policy and guidelines on providing standardised care for women who had a previous CS was also highlighted. Conclusion Midwives and doctors in this study were positively oriented towards assisting and supporting women to attempt a VBAC. Care providers considered that women who have experienced a prior CS need access to midwifery continuity of care with a focus on support, information-sharing and effective communication

Resolving content moderation dilemmas between free speech and harmful misinformation

When moderating content online, two key values may come into conflict: protecting freedom of expression and preventing harm. Robust rules based in part on how citizens think about these moral dilemmas are necessary to deal with the unprecedented scale and urgency of this conflict in a principled way. Yet little is known about people’s judgments and preferences around content moderation. We examined such moral dilemmas in a conjoint survey experiment where respondents (N=2,564) indicated whether they would remove problematic social media posts on election denial, anti-vaccination, Holocaust denial, and climate change denial and whether they would take punitive action against the accounts. Respondents were shown key information about the user and their post, as well as the consequences of the misinformation. The majority preferred quashing harmful misinformation over protecting free speech. Respondents were more likely to remove posts and suspend accounts if the consequences were severe and if it was a repeated offence. Features related to the account itself (the person behind the account, their partisanship, and the number of followers) had little to no effect on respondents’ decisions. Content moderation of harmful misinformation was a partisan issue: Across all four scenarios, Republicans were consistently less willing than Democrats or Independents to delete posts or penalize the accounts that posted them. Our results can inform the design of transparent rules of content moderation for human and algorithmic moderators.Effective Protection of Fundamental Rights in a pluralist worl

Management of Dyspnea in Advanced Cancer: ASCO Guideline.

PURPOSE To provide guidance on the clinical management of dyspnea in adult patients with advanced cancer. METHODS ASCO convened an Expert Panel to review the evidence and formulate recommendations. An Agency for Healthcare Research and Quality (AHRQ) systematic review provided the evidence base for nonpharmacologic and pharmacologic interventions to alleviate dyspnea. The review included randomized controlled trials (RCTs) and observational studies with a concurrent comparison group published through early May 2020. The ASCO Expert Panel also wished to address dyspnea assessment, management of underlying conditions, and palliative care referrals, and for these questions, an additional systematic review identified RCTs, systematic reviews, and guidelines published through July 2020. RESULTS The AHRQ systematic review included 48 RCTs and two retrospective cohort studies. Lung cancer and mesothelioma were the most commonly addressed types of cancer. Nonpharmacologic interventions such as fans provided some relief from breathlessness. Support for pharmacologic interventions was limited. A meta-analysis of specialty breathlessness services reported improvements in distress because of dyspnea. RECOMMENDATIONS A hierarchical approach to dyspnea management is recommended, beginning with dyspnea assessment, ascertainment and management of potentially reversible causes, and referral to an interdisciplinary palliative care team. Nonpharmacologic interventions that may be offered to relieve dyspnea include airflow interventions (eg, a fan directed at the cheek), standard supplemental oxygen for patients with hypoxemia, and other psychoeducational, self-management, or complementary approaches. For patients who derive inadequate relief from nonpharmacologic interventions, systemic opioids should be offered. Other pharmacologic interventions, such as corticosteroids and benzodiazepines, are also discussed

The Grizzly, April 6, 1993

Mr. Ursinus, 1993 • ProTheatre\u27s Actors Deliver in Thornwood • Another Weekend of Fighting in Reimert • Changes in Housing Selection • Wismer Renovations • Waco Standoff Continues • Your Chance to Give • Access to the Vault • Congratulations to P.O.D. for Excelling in Blood Drive • Daffodils for Service • Senior Profile: Allen Clowers • Why Can\u27t I Pick my Classes? • Letters to the Editor • Seniors Return, but Bears Fall • Men\u27s LAX Wants to Be Official • Men\u27s Tennis Young and Improvinghttps://digitalcommons.ursinus.edu/grizzlynews/1314/thumbnail.jp

Solitary splenic metastasis from ovarian carcinosarcoma: a case report

<p>Abstract</p> <p>Introduction</p> <p>Metastatic tumors to the spleen are rare but are usually found in conjunction with metastasis to other organs. The most common sources of splenic metastasis are breast, lung and colorectal cancers as well as melanoma and ovarian carcinoma. A solitary carcinosarcoma metastasis to the spleen of any origin is very rare. To the best of our knowledge, there are fewer than 30 reported cases of ovarian primary tumors with solitary metastasis to the spleen, and only three solitary primary carcinosarcomas to the spleen have been reported, of which one is female. We present what is, to the best of our knowledge, the first case of a solitary metastatic carcinosarcoma to the spleen arising from a primary ovarian carcinsarcoma.</p> <p>Case presentation</p> <p>A 72-year-old Hispanic woman status post-total abdominal hysterectomy for ovarian carcinosarcoma presented with complaints of early satiety and abdominal pain for the past two months with a 30-lb unintentional weight loss. An initial computed tomographic scan of her abdomen and pelvis revealed a 30 cm × 27 cm splenic mass with displacement of the left kidney, stomach and liver. The patient was found to have a solitary metastatic carcinosarcoma of the spleen with biphasic epithelial (carcinomatous) and mesenchymal (sarcomatous) elements consistent with carcinosarcoma.</p> <p>Conclusion</p> <p>Carcinosarcoma of the spleen is a rare tumor. Carcinosarcomas are a biphasic neoplasm comprising malignant epithelial and mesenchymal components arising from a stem cell capable of differentiation. They can arise anywhere in the female genital tract, most commonly from the endometrium. Even though it is rare, carcinosarcomas can metastasize to the spleen. This unique case of a solitary splenic metastasis from ovarian carcinosarcoma has particular interest in medicine, especially for the specialties of surgical oncology, pathology and hematology/oncology.</p