1,886 research outputs found
Breaking down the language of racism:a computerised linguistic analysis of racist groups’ self-defining online statements
The Internet represents a powerful tool for racist groups to build a sense of group consciousness and promote their cause. In the current study, we examined the language used by racist (n = 87), anti-racist (n = 50), and nonactivist (n = 1379) groups when describing their self-defining beliefs online. We used computerized linguistic analysis software to measure psychological indicators and antecedents of group consciousness and to examine the persuasive techniques used in online group communication. Racist and anti-racist groups were similar on some linguistic indicators of group consciousness (e.g., use of words reflecting perceived injustice), but differed on others (e.g., use of words reflecting group identification). Linguistic indicators of antecedents of group consciousness (moral foundations and focus on religion) differed across groups, with racist groups focused more on purity, respect for authority, and religion, and less on fairness than anti-racist groups. Racist groups also used less cognitively complex language than nonactivist groups (but similar levels to anti-racist groups). Our results contribute to understanding how racist groups promote their self-defining beliefs online, and identify several key factors that should be considered when designing policies to reduce racist groups' growth and impact
Energetics of the primary electron transfer reaction revealed by ultrafast spectroscopy on modified bacterial reaction centers
The modification of reaction centers from Rhodobacter sphaeroides by the introduction of pheophytins instead of bacteriopheophytins leads to interesting changes in the primary photosynthetic reaction: long-living populations of the excited electronic state of the special pair P* and the bacteriochlorophyll anion B−A show up. The data allow the determination of the energetics in the reaction center. The free energy of the first intermediate P+B−A, where the electron has reached the accessory bacteriochlorophyll BA lies ≈ 450 cm−1 below the initially excited special pair P*
Two-Dimensional Infrared Spectroscopy of Antiparallel β-Sheet Secondary Structure
We investigate the sensitivity of femtosecond Fourier transform two-dimensional infrared spectroscopy to protein secondary structure with a study of antiparallel β-sheets. The results show that 2D IR spectroscopy is more sensitive to structural differences between proteins than traditional infrared spectroscopy, providing an observable that allows comparison to quantitative models of protein vibrational spectroscopy. 2D IR correlation spectra of the amide I region of poly-L-lysine, concanavalin A, ribonuclease A, and lysozyme show cross-peaks between the IR-active transitions that are characteristic of amide I couplings for polypeptides in antiparallel hydrogen-bonding registry. For poly-L-lysine, the 2D IR spectrum contains the eight-peak structure expected for two dominant vibrations of an extended, ordered antiparallel β-sheet. In the proteins with antiparallel β-sheets, interference effects between the diagonal and cross-peaks arising from the sheets, combined with diagonally elongated resonances from additional amide transitions, lead to a characteristic “Z”-shaped pattern for the amide I region in the 2D IR spectrum. We discuss in detail how the number of strands in the sheet, the local configurational disorder in the sheet, the delocalization of the vibrational excitation, and the angle between transition dipole moments affect the position, splitting, amplitude, and line shape of the cross-peaks and diagonal peaks.
Cohomology of bundles on homological Hopf manifold
We discuss the properties of complex manifolds having rational homology of
including those constructed by Hopf, Kodaira and
Brieskorn-van de Ven. We extend certain previously known vanishing properties
of cohomology of bundles on such manifolds.As an application we consider
degeneration of Hodge-deRham spectral sequence in this non Kahler setting.Comment: To appear in Proceedings of 2007 conference on Several complex
variables and Complex Geometry. Xiamen. Chin
Efficacy and safety of cangrelor in patients with peripheral artery disease undergoing percutaneous coronary intervention – Insights from the CHAMPION program
Abstract Background Peripheral artery disease (PAD) is associated with an increased risk of ischemic events following percutaneous coronary intervention (PCI). More aggressive antiplatelet therapy may mitigate this risk. The present study evaluates the efficacy of cangrelor in patients with PAD undergoing PCI. Methods and results This is a pooled analysis from the CHAMPION PCI, CHAMPION PLATFORM, AND CHAMPION PHOENIX trials, evaluating cangrelor versus either clopidogrel or placebo in PCI patients. The occurrence of the primary endpoint of death, myocardial infarction, or ischemia-driven revascularization (IDR) was assessed in patients with and without PAD. GUSTO severe bleeding at 48 h was also evaluated. There were 1720 (7%) patients with PAD and 22,802 (93%) without PAD. After adjustment for differences in baseline variables, PAD patients, compared with those without PAD, experienced increased odds of the primary endpoint (OR [95% CI] = 1.27 [0.91, 1.77], P = 0.16) and GUSTO severe bleeding (OR [95% CI] = 3.24 [1.28, 8.21], P = 0.01). In PAD patients, the primary endpoint was 4.7% with cangrelor vs. 7.2% with clopidogrel (OR [95% CI] = 0.64 [0.42,0.96]); in patients without PAD the primary endpoint was 3.5% with cangrelor vs. 4.2% with clopidogrel (OR [95% CI] = 0.83 [0.72,0.95]), P-interaction 0.23. Among patients with or without PAD, there was no significant difference in the rate of GUSTO severe bleeding with cangrelor compared with control, P-interaction 0.86. Conclusions In a pooled analysis of the CHAMPION studies, PAD was associated with increased rates of ischemic and bleeding complications. Cangrelor reduced the odds of ischemic events, without increasing GUSTO severe bleeding. Clinical trial registration clinicaltrials.gov identifiers: CHAMPION PCI ( NCT00305162 ), CHAMPION PLATFORM ( NCT00385138 ), CHAMPION PHOENIX ( NCT01156571
Two-Dimensional Electronic Spectroscopy of Chlorophyll a: Solvent Dependent Spectral Evolution
The interaction of the monomeric chlorophyll Q-band electronic transition with solvents of differing physical-chemical properties is investigated through two-dimensional electronic spectroscopy (2DES). Chlorophyll constitutes the key chromophore molecule in light harvesting complexes. It is well-known that the surrounding protein in the light harvesting complex fine-tunes chlorophyll electronic transitions to optimize energy transfer. Therefore, an understanding of the influence of the environment on the monomeric chlorophyll electronic transitions is important. The Q-band 2DES is inhomogeneous at early times, particularly in hydrogen bonding polar solvents, but also in nonpolar solvents like cyclohexane. Interestingly this inhomogeneity persists for long times, even up to the nanosecond time scale in some solvents. The reshaping of the 2DES occurs over multiple time scales and was assigned mainly to spectral diffusion. At early times the reshaping is Gaussian-like, hinting at a strong solvent reorganization effect. The temporal evolution of the 2DES response was analyzed in terms of a Brownian oscillator model. The spectral densities underpinning the Brownian oscillator fitting were recovered for the different solvents. The absorption spectra and Stokes shift were also properly described by this model. The extent and nature of inhomogeneous broadening was a strong function of solvent, being larger in H-bonding and viscous media and smaller in nonpolar solvents. The fastest spectral reshaping components were assigned to solvent dynamics, modified by interactions with the solute
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Development of an optical digital ionization chamber
We are developing a new device for optically detecting and imaging the track of a charged particle in a gas. The electrons in the particle track are made to oscillate rapidly by the application of an external, short-duration, high-voltage, RF electric field. The excited electrons produce additional ionization and electronic excitation of the gas molecules in their immediate vicinity, leading to copious light emission (fluorescence) from the selected gas, allowing the location of the electrons along the track to be determined. Two digital cameras simultaneously scan the emitted light across two perpendicular planes outside the chamber containing gas. The information thus obtained for a given track can be used to infer relevant quantities for microdosimetry and dosimetry, e.g., energy deposited, LET, and track structure in the gas. The design of such a device now being constructed and methods of obtaining the dosimetric data from the digital output will be described. 4 refs., 4 figs
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Digital characterization of recoil charged-particle tracks for neutron measurements
We are developing a new optical ionization detector for imaging the track of a charged neutron-recoil particle in a gas. Electrons produced in the path of the recoil particle are excited by an external, high-voltage, RF, electric field of short duration. Their oscillatory motion causes ionization and excitation of nearby gas molecules, which then emit light in subsequent de-excitation. Two digital cameras image the optical radiation across two perpendicular planes and analyze it for the numbers of electrons in various volume elements along the track. These numbers constitute the digital characterization of the track. This information can then be used to infer the energy deposited in the track and the track LET in the gas. We have now observed alpha-particle tracks in a chamber utilizing these principles. The application of such a device for neutron dosimetry and neutron spectrometry will be described. 4 refs., 3 figs
Precise Measurements of Direct CP Violation, CPT Symmetry, and Other Parameters in the Neutral Kaon System
We present precise tests of CP and CPT symmetry based on the full dataset of
K to pipi decays collected by the KTeV experiment at Fermi National Accelerator
Laboratory during 1996, 1997, and 1999. This dataset contains 16 million K to
2pi0 and 69 million K to pi+pi- decays. We measure the direct CP violation
parameter Re(epsilon'/epsilon) = (19.2 pm 2.1)x10-4. We find the KL-KS mass
difference Deltam = (5270 pm 12)x10^6 hbar/s and the KS lifetime tauS = (89.62
pm 0.05)x10-12 s. We also measure several parameters that test CPT invariance.
We find the difference between the phase of the indirect CP violation
parameter, epsilon, and the superweak phase, phi_epsilon - phi_SW = (0.40 pm
0.56) degrees. We measure the difference of the relative phases between the CP
violating and CP conserving decay amplitudes for K to pi+pi- (phi+-) and for K
to 2pi0 (phi00), Delta phi = (0.30 pm 0.35) degrees. From these phase
measurements, we place a limit on the mass difference between K0 and K0bar,
DeltaM < 4.8 x 10-19 GeV/c^2 at 95% C.L. These results are consistent with
those of other experiments, our own earlier measurements, and CPT symmetry.Comment: 28 pages, 30 figures; removed extra figur
First Observation of the decay KL -> pi0 e e gamma
We report on the first observation of the decay KL -> pi0 ee gamma by the
KTeV E799 experiment at Fermilab. Based upon a sample of 48 events with an
estimated background of 3.6 +/- 1.1 events, we measure the KL -> pi0 ee gamma
branching ratio to be (2.34 +/- 0.35 +/- 0.13)x10^{-8}. Our data agree with
recent O(p^6) calculations in chiral perturbation theory that include
contributions from vector meson exchange through the parameter a_V. A fit was
made to the KL -> pi0 ee gamma data for a_V with the result -0.67 +/- 0.21 +/-
0.12, which is consistent with previous results from KTeV.Comment: Submitted to Physical Review Letters, 5 pages, 5 figure
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