The Mid-IR Contribution Of Dust Enshrouded Stars In Six Nearby Galaxies

We measure the integrated contributions of dusty AGB stars and other luminous red mid-IR sources to the mid-IR luminosities of 6 galaxies (M81, NGC 2403, NGC 300, M33 and the Magellanic Clouds). We find the dusty AGB stars whose mid-IR fluxes are dominated by dust rather than photospheric emission contribute from 0.6% (M81) to 5.6% (SMC) of the 3.6 micron flux and 1.0% (M81) to 10.1% (SMC) of the 4.5 micron flux. We find a trend of decreasing AGB contribution with increasing galaxy metallicity, luminosity and mass and decreasing SSFR. However, these galaxy properties are strongly correlated in our sample and the simplest explanation of the trend is galaxy metallicity. Bright, red sources other than dusty AGB stars represent a smaller fraction of the luminosity, ~1.2% at 3.6 microns, however their dust is likely cooler and their contributions are likely larger at longer wavelengths. Excluding the SMC, the contribution from these red sources correlates with the specific star formation rate as we would expect for massive stars. In total, after correcting for dust emission at other wavelengths, the dust around AGB stars radiates 0.1-0.8% of the bolometric luminosities of the galaxies. Thus, hot dust emission from AGB and other luminous dusty stars represent a small fraction of the total luminosities of the galaxies but a significant fraction of their mid-IR emissions.Comment: 9 pages, 6 figures, published in ApJ. For a brief video explaining the key results of this paper, see http://www.youtube.com/user/OSUAstronom

Elevated plasma levels of TIMP-3 are associated with a higher risk of acute respiratory distress syndrome and death following severe isolated traumatic brain injury.

BackgroundComplications after injury, such as acute respiratory distress syndrome (ARDS), are common after traumatic brain injury (TBI) and associated with poor clinical outcomes. The mechanisms driving non-neurologic organ dysfunction after TBI are not well understood. Tissue inhibitor of matrix metalloproteinase-3 (TIMP-3) is a regulator of matrix metalloproteinase activity, inflammation, and vascular permeability, and hence has plausibility as a biomarker for the systemic response to TBI.MethodsIn a retrospective study of 182 patients with severe isolated TBI, we measured TIMP-3 in plasma obtained on emergency department arrival. We used non-parametric tests and logistic regression analyses to test the association of TIMP-3 with the incidence of ARDS within 8 days of admission and in-hospital mortality.ResultsTIMP-3 was significantly higher among subjects who developed ARDS compared with those who did not (median 2810 pg/mL vs. 2260 pg/mL, p=0.008), and significantly higher among subjects who died than among those who survived to discharge (median 2960 pg/mL vs. 2080 pg/mL, p<0.001). In an unadjusted logistic regression model, for each SD increase in plasma TIMP-3, the odds of ARDS increased significantly, OR 1.5 (95% CI 1.1 to 2.1). This association was only attenuated in multivariate models, OR 1.4 (95% CI 1.0 to 2.0). In an unadjusted logistic regression model, for each SD increase in plasma TIMP-3, the odds of death increased significantly, OR 1.7 (95% CI 1.2 to 2.3). The magnitude of this association was greater in a multivariate model adjusted for markers of injury severity, OR 1.9 (95% CI 1.2 to 2.8).DiscussionTIMP-3 may play an important role in the biology of the systemic response to brain injury in humans. Along with clinical and demographic data, early measurements of plasma biomarkers such as TIMP-3 may help identify patients at higher risk of ARDS and death after severe isolated TBI.Level of evidenceIII

Early respiratory viral infections in infants with cystic fibrosis

This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.Background Viral infections contribute to morbidity in cystic fibrosis (CF), but the impact of respiratory viruses on the development of airway disease is poorly understood. Methods Infants with CF identified by newborn screening were enrolled prior to 4 months of age to participate in a prospective observational study at 4 centers. Clinical data were collected at clinic visits and weekly phone calls. Multiplex PCR assays were performed on nasopharyngeal swabs to detect respiratory viruses during routine visits and when symptomatic. Participants underwent bronchoscopy with bronchoalveolar lavage (BAL) and a subset underwent pulmonary function testing. We present findings through 8.5 months of life. Results Seventy infants were enrolled, mean age 3.1 ± 0.8 months. Rhinovirus was the most prevalent virus (66%), followed by parainfluenza (19%), and coronavirus (16%). Participants had a median of 1.5 viral positive swabs (range 0–10). Past viral infection was associated with elevated neutrophil concentrations and bacterial isolates in BAL fluid, including recovery of classic CF bacterial pathogens. When antibiotics were prescribed for respiratory-related indications, viruses were identified in 52% of those instances. Conclusions Early viral infections were associated with greater neutrophilic inflammation and bacterial pathogens. Early viral infections appear to contribute to initiation of lower airway inflammation in infants with CF. Antibiotics were commonly prescribed in the setting of a viral infection. Future investigations examining longitudinal relationships between viral infections, airway microbiome, and antibiotic use will allow us to elucidate the interplay between these factors in young children with CF

Towards the development of a hybrid-integrated chip interferometer for online surface profile measurements

Non-destructive testing and online measurement of surface features are pressing demands in manufacturing. Thus optical techniques are gaining importance for characterization of complex engineering surfaces. Harnessing integrated optics for miniaturization of interferometry systems onto a silicon wafer and incorporating a compact optical probe would enable the development of a handheld sensor for embedded metrology applications. In this work, we present the progress in the development of a hybrid photonics based metrology sensor device for online surface profile measurements. The measurement principle along with test and measurement results of individual components has been presented. For non-contact measurement, a spectrally encoded lateral scanning probe based on the laser scanning microscopy has been developed to provide fast measurement with lateral resolution limited to the diffraction limit. The probe demonstrates a lateral resolution of ∼3.6 μm while high axial resolution (sub-nanometre) is inherently achieved by interferometry. Further the performance of the hybrid tuneable laser and the scanning probe was evaluated by measuring a standard step height sample of 100 nm

Violent quenching : Molecular Gas Blown to 1000 km s -1 during a Major Merger

Accepted for publication in ApJ LettersWe present Atacama Large Millimeter/submillimeter Array observations of a massive () compact ( pc) merger remnant at z = 0.66 that is driving a 1000 km s -1 outflow of cool gas, with no observational trace of an active galactic nucleus (AGN). We resolve molecular gas on scales of approximately 1-2 kpc, and our main finding is the discovery of a wing of blueshifted CO J(2 → 1) emission out to-1000 km s -1 relative to the stars. We argue that this is the molecular component of a multiphase outflow, expelled from the central starburst within the past 5 Myr through stellar feedback, although we cannot rule out previous AGN activity as a launching mechanism. If the latter is true, then this is an example of a relic multiphase AGN outflow. We estimate a molecular mass outflow rate of approximately 300 M o yr -1, or about one third of the 10 Myr-Averaged star formation rate. This system epitomizes the multiphase "blowout" episode following a dissipational major merger-a process that has violently quenched central star formation and supermassive black hole growth.Peer reviewedFinal Accepted Versio

Influence of Gravity on noncommutative Dirac equation

In this paper, we investigate the influence of gravity and noncommutativity on Dirac equation. By adopting the tetrad formalism, we show that the modified Dirac equation keeps the same form. The only modification is in the expression of the covariant derivative. The new form of this derivative is the product of its counterpart given in curved space-time with an operator which depends on the noncommutative $\theta$-parameter. As an application, we have computed the density number of the created particles in presence of constant strong electric field in an anisotropic Bianchi universe.Comment: 9 pages, correct some miprints, Accepted for publication in journal of Mod. Phys. Letters