1,995 research outputs found

    Training on Establishing Climate-Smart Villages (CSVs) in Myanmar to Improve Food Security and Resilience in Agriculture

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    This training on establish Climate-Smart Villages (CSVs) in Myanmar was a collaborative effort of the Food Security Working Group (FSWG) and the Myanmar Program of the International Institute of Rural Reconstruction. This was supported in part by donors of the FSWG and the International Development Research Center-Canada through the 3-year action research project of IIRR-Myanmar in 4 CSVs. The overall goal of this training was to increase the understanding of the concepts, processes and tools in implementing of CSVs as an approach to build climate resilience among small-holder farmers, achieve nutrition security and gender equality in Myanmar. It was aimed for local NGOs and members of the Food Security Working Group (FSWG), Myanmar’s largest alliance of development organizations advocating for food security and sustainable livelihoods in Myanmar. This training was part of IIRR-Myanmar’s out-scaling pathway by engaging and building capacities of local civil societies to replicate the CSV approach as platforms to promote climate smart agriculture in Myanmar

    Fostering local adaptation platforms for agriculture: How context specific climate-smart villages (CSVs) can relate to local adaptation efforts.

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    Local adaptation platforms help empower sub-national and local government players, civil society organizations, and public-private partnerships in demonstrating the validity of agro-ecology-specific solutions to current and future climate change impacts. This brief discusses how Climate-Smart Villages, good examples of local adaptation platform, have served as centers for discovery, adaptation, learning, and sharing of climate-smart agriculture in local communities

    Pathways to Attaining a Food Secure Philippines through a Competitive and Climate-Resilient Agri-Fisheries Sector

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    This document highlights the key messages drawn from climate adaptation efforts and events done with Philippines’ Department of Agriculture-Regional Field Offices (DA-RFOs) across the country. This brief, developed for the Climate Change Consciousness Week, offers DA a synthesis of lessons from the Adaptation and Mitigation Initiative in Agriculture (AMIA) village experience as a bankable model for establishing context specific, local adaptation platforms for developing and disseminating CRA technologies and processes. This brief also offers valuable policy insights for the Philippines’ National Adaptation Plan

    Experiment K-6-03. Gravity and skeletal growth, part 1. Part 2: Morphology and histochemistry of bone cells and vasculature of the tibia; Part 3: Nuclear volume analysis of osteoblast histogenesis in periodontal ligament cells; Part 4: Intervertebral disc swelling pressure associated with microgravity

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    Bone area, bone electrophysiology, bone vascularity, osteoblast morphology, and osteoblast histogenesis were studied in rats associated with Cosmos 1887. The results suggest that the synchronous animals were the only group with a significantly larger bone area than the basal group, that the bone electrical potential was more negative in flight than in the synchronous rats, that the endosteal osteoblasts from flight rats had greater numbers of transitional Golgi vesicles but no difference in the large Golgi saccules or the alkaline phosphatase activity, that the perioteal vasculature in the shaft of flight rats often showed very dense intraluminal deposits with adjacent degenerating osteocytes as well as lipid accumulations within the lumen of the vessels and sometimes degeneration of the vascular wall (this change was not present in the metaphyseal region of flight animals), and that the progenitor cells decreased in flight rats while the preosteoblasts increased compared to controls. Many of the results suggest that the animals were beginning to recover from the effects of spaceflight during the two day interval between landing and euthanasia; flight effects, such as the vascular changes, did not appear to recover

    The AMIA Experience: Supporting local actions for Climate Resilient Agriculture

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    The brief tackles how the Adaptation and Mitigation Initiative in Agriculture (AMIA) Program of the Philippines’ Department of Agriculture (DA) served as a platform for supporting local actions for climate resilient agriculture. The document discusses a number of key lessons emerging from the AMIA Village experience on the importance of local platforms for adaptation in the form of Climate-Smart Villages towards overall resilience building of the sector

    On production and asymmetric focusing of flat electron beams using rectangular capillary discharge plasmas

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    A method for the asymmetric focusing of electron bunches, based on the active plasma lensing technique is proposed. This method takes advantage of the strong inhomogeneous magnetic field generated inside the capillary discharge plasma to focus the ultrarelativistic electrons. The plasma and magnetic field parameters inside the capillary discharge are described theoretically and modeled with dissipative magnetohydrodynamic computer simulations enabling analysis of the capillaries of rectangle cross-sections. Large aspect ratio rectangular capillaries might be used to transport electron beams with high emittance asymmetries, as well as assist in forming spatially flat electron bunches for final focusing before the interaction point.Comment: 16 pages, 7 figures, 1 tabl

    Diclofenac-β-cyclodextrin for colonic drug targeting: in vivo performance in rats

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    The aim of this in vivo study was to assess the ability of the prodrug conjugate diclofenac-β-cyclodextrin to release diclofenac in the colon following oral administration, using sulfapyridine (a metabolite of sulfasalazine) as a marker of colonic absorption. Two groups of rats were used; the test rats received a suspension containing the two prodrugs, diclofenac-β-cyclodextrin and sulfasalazine, while the control rats received a suspension containing the corresponding free drugs, sodium diclofenac and sulfapyridine. The rats were fasted overnight with free access to water before and throughout the first 12 hours of the study. Blood was collected from the tail vein at pre-determined time points and the plasma analyzed for the concentrations of diclofenac and sulfapyridine. Following the oral administration of the two prodrugs, a more extended absorption profile was observed and Cmax was achieved 10 hours post-dose, in contrast to rapid absorption of the free drugs (tmax of diclofenac being 1.3 h, and that of sulfapyridine being 2.1 h) . In addition to a later tmax, conjugation of diclofenac to β-cyclodextrin also resulted in a reduced Cmax and a reduced AUC. The same tmax for diclofenac-β-cyclodextrin as for sulfasalazine confirms the colonic metabolism of diclofenac-β-cyclodextrin. This study shows the potential of this new cyclodextrin-based prodrug to target and release diclofenac specifically in the colon following oral administration
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