Reproductive Issues in Women with Turner Syndrome

Turner syndrome is one of the most common chromosomal abnormalities affecting female infants. The severity of clinical manifestations varies and it affects multiple organ systems. Women with Turner syndrome have a 3-fold increase in mortality, which becomes even more pronounced in pregnancy. Reproductive options include adoption or surrogacy, assisted reproductive techniques, and in rare cases spontaneous pregnancy. Risks for women with Turner syndrome during pregnancy include aortic disorders, hepatic disease, thyroid disease, type 2 diabetes, and cesarean section delivery. Providers must be familiar with the risks and recommendations in caring for women with Turner syndrome of reproductive age

Considering Contingencies of Gambling Research in Conjunction with the \u3ci\u3eBehavior Analyst Certification Board Professional and Ethical Compliance Code\u3c/i\u3e

The issues that are the focus of this paper can be exemplified in two questions relevant to danger and validity in behavioral gambling research: Is there danger of reinforcing problem gambling behavior in experiments where gambling is a dependent variable? And, do reliable laboratory effects represent something key in development or maintenance of gambling problems, or have some other applied pragmatic value? Behavior analytic research is performed in an ethical manner, and the concerns of the above questions are typically minimized. The persistence of the questions is discussed, as well as the value of research in relation to behavioral treatments. These issues are discussed in conjunction with the Behavior Analyst Certification Board Professional and Ethical Compliance Code

Dark/Visible Parallel Universes and Big Bang Nucleosynthesis

We develop a model for visible matter-dark matter interaction based on the exchange of a massive gray boson called herein the Mulato. Our model hinges on the assumption that all known particles in the visible matter have their counterparts in the dark matter. We postulate six families of particles five of which are dark. This leads to the unavoidable postulation of six parallel worlds, the visible one and five invisible worlds. A close study of big bang nucleosynthesis (BBN), baryon asymmetries, cosmic microwave background (CMB) bounds, galaxy dynamics, together with the Standard Model assumptions, help us to set a limit on the mass and width of the new gauge boson. Modification of the statistics underlying the kinetic energy distribution of particles during the BBN is also discussed. The changes in reaction rates during the BBN due to a departure from the Debye-Hueckel electron screening model is also investigated.Comment: Invited talk at the Workshops "CompStar: the physics and astrophysics of compact stars", Tahiti, June 4-8, 2012, "New Directions in Nuclear Astrophysics", Castiglion Fiorentino, Italy, June 18-22, 2012, and "Carpathian Summer School of Physics", Sinaia, Romania, June 24 - July 7, 2012. To be published in AIP Proceeding

A Brief Behavioral Intervention of Harm Reduction for Online Poker Players

Given the high rates of gambling in the United States and the growing population of problem and pathological (disordered) gamblers, there is a need for effective interventions which will eliminate or reduce disordered gambling, or, at minimum, reduce harm resulting from disordered gambling. High-risk populations for development of disordered gambling include college students and online poker players. This study sought to develop and test a brief behavioral intervention for decreasing monetary loss, time spent gambling, and risky betting for college-aged self-identified problem gamblers who play online poker. This study included four participants in a multiple baseline across participants. Post-intervention, all participants gambled fewer days overall, and three of four participants lost less money overall. The fourth participant was never at a net monetary los

Bicalutamide as an Androgen Blocker With Secondary Effect of Promoting Feminization in Male-to-Female Transgender Adolescents

PURPOSE: The purpose of the study was to describe the novel use of bicalutamide in transgender youth. METHODS: This is a retrospective review of patients with gender dysphoria followed in the pediatric endocrine clinic at Riley Hospital for Children. RESULTS: Of 104 patients with gender dysphoria, 23 male-to-female adolescents received bicalutamide 50 mg daily as a second-line puberty blocker after insurance company denial of a gonadotropin-releasing hormone analog. Six patients received estrogen concurrently. Of 13 patients treated exclusively with bicalutamide seen in follow-up, 84.6% had breast development within 6 months, the majority being ≥ Tanner stage III. CONCLUSIONS: Bicalutamide may be an alternative to gonadotropin-releasing hormone analogs in transgender male-to-female youth who are also ready to undergo physical transition

How much money does the Voluntary Furlough Program save the State Budget and Control Board?

The purpose of this project is to determine the best methods to measure and report cost savings as a result of the implementation of a voluntary furlough program for the South Carolina Budget and Control Board

Adrenal Tumors in Childhood

Adrenocortical tumors are rare in children and usually present with virilization before age 5 years. They may also present as Cushing syndrome or with mixed effects