3,150 research outputs found

    alpha-nucleus potentials for the neutron-deficient p nuclei

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    alpha-nucleus potentials are one important ingredient for the understanding of the nucleosynthesis of heavy neutron-deficient p nuclei in the astrophysical gamma-process where these p nuclei are produced by a series of (gamma,n), (gamma,p), and (gamma,alpha) reactions. I present an improved alpha-nucleus potential at the astrophysically relevant sub-Coulomb energies which is derived from the analysis of alpha decay data and from a previously established systematic behavior of double-folding potentials.Comment: 6 pages, 3 figures, accepted for publication in Phys. Rev.

    Optimization of Undersampling Parameters for 3D Intracranial Compressed Sensing MR Angiography at 7 Tesla

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    Purpose: 3D Time-of-flight (TOF) MR Angiography (MRA) can accurately visualize the intracranial vasculature, but is limited by long acquisition times. Compressed sensing (CS) reconstruction can be used to substantially accelerate acquisitions. The quality of those reconstructions depends on the undersampling patterns used in the acquisitions. In this work, optimized sets of undersampling parameters using various acceleration factors for Cartesian 3D TOF-MRA are established. Methods: Fully-sampled datasets acquired at 7T were retrospectively undersampled using variable-density Poisson-disk sampling with various autocalibration region sizes, polynomial orders, and acceleration factors. The accuracy of reconstructions from the different undersampled datasets was assessed using the vessel-masked structural similarity index. Results were compared for four imaging volumes, acquired from two different subjects. Optimized undersampling parameters were validated using additional prospectively undersampled datasets. Results: For all acceleration factors, using a fully-sampled calibration area of 12x12 k-space lines and a polynomial order of around 2-2.4 resulted in the highest image quality. The importance of sampling parameter optimization was found to increase for higher acceleration factors. The results were consistent across resolutions and regions of interest with vessels of varying sizes and tortuosity. In prospectively undersampled acquisitions, using optimized undersampling parameters resulted in a 7.2% increase in the number of visible small vessels at R = 7.2. Conclusion: The image quality of CS TOF-MRA can be improved by appropriate choice of undersampling parameters. The optimized sets of parameters are independent of the acceleration factor.Comment: Manuscript to be submitted to Magnetic Resonance in Medicin

    Faddeev approach to the octet and decuplet baryons

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    A relativistic Faddeev model for the baryon octet is extended to treat the baryon decuplet. We find that after determining the model parameters in the mesonic sector the masses of both nucleon and delta deviate by less than 5\% from the experimental data and show only a very weak dependence on the constituent quark mass.Comment: 9 page

    Fecal shedding and tissue infections demonstrate transmission of Mycobacterium avium subsp. paratuberculosis in group-housed dairy calves

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    International audienceAbstractCurrent Johne’s disease control programs primarily focus on decreasing transmission of Mycobacterium avium subsp. paratuberculosis (MAP) from infectious adult cows to susceptible calves. However, potential transmission between calves is largely overlooked. The objective was to determine the extent of MAP infection in calves contact-exposed to infectious penmates. Thirty-two newborn Holstein–Friesian calves were grouped into 7 experimental groups of 4, consisting of 2 inoculated (IN) calves, and 2 contact-exposed (CE) calves, and 1 control pen with 4 non-exposed calves. Calves were group housed for 3 months, with fecal samples were collected 3 times per week, blood and environmental samples weekly, and tissue samples at the end of the trial. The IN calves exited the trial after 3 months of group housing, whereas CE calves were individually housed for an additional 3 months before euthanasia. Control calves were group-housed for the entire trial. All CE and IN calves had MAP-positive fecal samples during the period of group housing; however, fecal shedding had ceased at time of individual housing. All IN calves had MAP-positive tissue samples at necropsy, and 7 (50%) of the CE had positive tissue samples. None of the calves had a humoral immune response, whereas INF-γ responses were detected in all IN calves and 5 (36%) CE calves. In conclusion, new MAP infections occurred due to exposure of infectious penmates to contact calves. Therefore, calf-to-calf transmission is a potential route of uncontrolled transmission on cattle farms

    Quantifying transmission of Mycobacterium avium subsp. paratuberculosis among group-housed dairy calves

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    International audienceAbstractJohne’s disease (JD) is a chronic enteritis caused by Mycobacterium avium subsp. paratuberculosis (MAP), with control primarily aimed at preventing new infections among calves. The aim of the current study was to quantify calf-to-calf transmission of MAP among penmates in an experimental trial. Newborn Holstein bull calves (n = 32) were allocated into pens of 4, with 2 inoculated (IN) calves and 2 calves that were contact exposed (CE). Calves were group-housed for 3 months, with frequent collection of fecal and blood samples and tissue collection after euthanasia. The basic reproduction ratio (R0) was estimated using a final size (FS) model with a susceptible-infected model, based on INF-γ ELISA and tissue culture followed by qPCR. In addition, the transmission rate parameter (β) for new shedding events was estimated using a general linearized method (GLM) model with a susceptible-infected-susceptible model based on culture, followed by qPCR, of fecal samples collected during group housing. The R0 was derived for IN and CE calves separately, due to a difference in susceptibility, as well as differences in duration of shedding events. Based on the FS model, interferon-γ results from blood samples resulted in a R0IG of 0.90 (0.24, 2.59) and tissue culture resulted in a R0T of 1.36 (0.45, 3.94). Based on the GLM model, the R0 for CE calves to begin shedding (R0CE) was 3.24 (1.14, 7.41). We concluded that transmission of MAP infection between penmates occurred and that transmission among calves may be an important cause of persistent MAP infection on dairy farms that is currently uncontrolled for in current JD control programs

    Evidence for transfer followed by breakup in 7Li + 65Cu

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    The observation of a large cross-section for the alpha + d channel compared to breakup into the alpha + t channel from an exclusive measurement for the 7Li+65Cu system at 25 MeV is presented. A detailed analysis of the angular distribution using coupled channels Born approximation calculations has provided clear evidence that the observed alpha + d events arise from a two step process, i.e. direct transfer to the 2.186 MeV (3+) resonance in the alpha + d continuum of 6Li followed by breakup, and are not due to final state interaction effects.Comment: 12 pages, 3 figures, To be published in Phys. Letts.

    Les temps pour comprendre des "petits curieux"

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    Financial phantasmagoria: corporate image-work in times of crisis

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    Our purpose in this article is to relate the real movements in the economy during 2008 to the ?image-work? of financial institutions. Over the period January?December 2008 we collected 241 separate advertisements from 61 financial institutions published in the Financial Times. Reading across the ensemble of advertisements for themes and evocative images provides an impression of the financial imaginaries created by these organizations as the global financial crisis unfolded. In using the term ?phantasmagoria? we move beyond its colloquial sense of a set of strange images designed to dazzle towards the more technical connotation used by Ranci�re (2004) who suggested that words and images can offer a trace of an overall determining set-up if they are torn from their obviousness so they become phantasmagoric figures. The key phantasmagoric figure we identify here is that of the financial institution as timeless, immortal and unchanging; a coherent and autonomous entity amongst other actors. This notion of uniqueness belies the commonality of thinking which precipitated the global financial crisis as well as the limited capacity for control of financial institutions in relation to market events. It also functions as a powerful naturalizing force, making it hard to question certain aspects of the recent period of ?capitalism in crisis?

    Origin of Relativistic Effects in the Reaction D(e,e'p)n at GeV Energies

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    In a series of recent publications, a new approach to the non-relativistic reduction of the electromagnetic current operator in calculations of electro-nuclear reactions has been introduced. In one of these papers, the conjecture that at energies of a few GeV, the bulk of the relativistic effects comes from the current and not from the nuclear dynamics was made, based on the large relativistic effects in the transverse-longitudinal response. Here, we explicitly compare a fully relativistic, manifestly covariant calculation performed with the Gross equation, with a calculation that uses a non-relativistic wave function and a fully relativistic current operator. We find very good agreement up to missing momenta of 400 MeV/c, thus confirming the previous conjecture. We discuss slight deviations in cross sections for higher missing momenta and their possible origin, namely p-wave contributions and off-shell effects.Comment: 25 pages, 11 figure

    Direct Infection and Replication of Naturally Occurring Hepatitis C Virus Genotypes 1, 2, 3 and 4 in Normal Human Hepatocyte Cultures

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    Hepatitis C virus (HCV) infection afflicts about 170 million individuals worldwide. However, the HCV life cycle is only partially understood because it has not been possible to infect normal human hepatocytes in culture. The current Huh-7 systems use cloned, synthetic HCV RNA expressed in hepatocellular carcinoma cells to produce virions, but these cells cannot be infected with naturally occurring HCV obtained from infected patients.Here, we describe a human hepatocyte culture permissible to the direct infection with naturally occurring HCV genotypes 1, 2, 3 and 4 in the blood of HCV-infected patients. The culture system mimics the biology and kinetics of HCV infection in humans, and produces infectious virions that can infect naïve human hepatocytes.This culture system should complement the existing systems, and may facilitate the understanding of the HCV life cycle, its effects in the natural host cell, the hepatocyte, as well as the development of novel therapeutics and vaccines
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