27 research outputs found
The effect of prolonged simulated non- gravitational environment on mineral balance in the adult male, volume 1 Final report
Effect of prolonged bed rest with simulated weightlessness on mineral balance in male adult - Vol.
Quantum interference due to crossed Andreev reflection in a d-wave superconductor with two nano-contacts
The crossed Andreev reflection in a hybrid nanostructure consisting of a
d-wave superconductor and two quantum wires is theoretically studied. When the
(110) oriented surface of the superconductor is in contact with the wires
parallel and placed close to each other, the Andreev bound state is formed by
the crossed Andreev reflection. The conductance has two resonance peaks well
below the gap structure in the case of tunnel contacts. These peaks originate
from the bonding and antibonding Andreev bound states of hole wave functions.Comment: 4 pages, 3 figure
Profiles of responses of immunological factors to different subtypes of Kawasaki disease
Neurotoxicity in the setting of pediatric atopic dermatitis treated with modified cyclosporine and itraconazole
Psoriasiform eruptions during Kawasaki disease (KD): A distinct phenotype
BackgroundA psoriasis-like eruption develops in a subset of patients with Kawasaki disease (KD).ObjectiveWe sought to systematically compare KD-associated psoriasiform eruptions with classic psoriasis and the outcomes of KD in children with and without this rash.MethodsThis was a retrospective study of 11 KD cases with a psoriasiform eruption matched 1:2 by age, gender, and ethnicity with psoriasis-only and KD-only controls. Genotyping was performed in 10 cases for a deletion of 2 late cornified envelope (LCE) genes, LCE3C_LCE3B-del, associated with increased risk for pediatric-onset psoriasis.ResultsSimilar to classic psoriasis, KD-associated eruptions were characterized clinically by well-demarcated, scaly pink plaques and histopathologically by intraepidermal neutrophils, suprabasilar keratin 16 expression, and increased Ki-67 expression. They showed less frequent diaper area involvement, more crust and serous exudate, and an enduring remission (91% vs 23% with confirmed resolution; P < .001). Frequency of LCE3C_LCE3B-del and major KD outcomes were similar between cases and controls.LimitationsThe study was limited by the small number of cases, treatment variation, and availability of skin biopsy specimens.ConclusionsAlthough the overall clinical and histopathologic findings were similar to conventional psoriasis, this appears to be a distinct phenotype with significantly greater propensity for remission. No adverse effect on KD outcomes was noted