4,044 research outputs found
Length-weight relationships of Cuban marine fishes
A total of 140 sets of parameters (a and b) of the length-weight relationships (LWR) of the form W=aL super(b) are presented for fishes caught in Cuban waters. These parameters cover 94 species of fish belonging to 43 families. Most of the parameters were compiled from 107 sets of published and unpublished studies. Twenty-five sets of parameters were from personal communications through colleagues in Cuba, while the remaining eight sets were estimated by the authors from unpublished data
Length-weight relationships of Cuban marine fishes
Length-weight relationships, Marine fish, Cuba,
Report on Tests and Measurements of Hadronic Interaction Properties with Air Showers
We present a summary of recent tests and measurements of hadronic interaction
properties with air showers. This report has a special focus on muon density
measurements. Several experiments reported deviations between simulated and
recorded muon densities in extensive air showers, while others reported no
discrepancies. We combine data from eight leading air shower experiments to
cover shower energies from PeV to tens of EeV. Data are combined using the
z-scale, a unified reference scale based on simulated air showers.
Energy-scales of experiments are cross-calibrated. Above 10 PeV, we find a muon
deficit in simulated air showers for each of the six considered hadronic
interaction models. The deficit is increasing with shower energy. For the
models EPOS-LHC and QGSJet-II.04, the slope is found significant at 8 sigma.Comment: Submitted to the Proceedings of UHECR201
NCI-MATCH Arms N & P: Phase II study of PI3K beta inhibitor GSK2636771 in patients (pts) with cancers (ca) with PTEN mutation/deletion (mut/del) or PTEN protein loss
Background: The NCI-MATCH trial is the largest national study (1173 sites) for ptswith relapsed/ refractory solid tumors, lymphomas and myeloma, which assigns tar-geted therapies based on individual tumor molecular alterations detected using theadapted Oncomine AmpliSeq panel (143 genes) and immunohistochemistry (IHC).We hypothesized that patients with PTEN-deficient cancers enrolled to Arms N and Pmay benefit from treatment with the PI3K beta-selective inhibitor GSK2636771.
Methods: Eligibility: relapsed/refractory ca, good end-organ function, and ECOG PS ≤ 1. Pts were screened for molecular alterations by centralized testing on fresh tumor biopsy and had deleterious PTEN mut/del without loss of expression (Arm N) or complete loss of cytoplasmic and nuclear PTEN staining on IHC (Arm P), and no other aberrations activating the PI3K/MTOR and MAPK pathways (mut in PIK3CA, PIK3R1, BRAF, KRAS, AKT1, TSC1/2, mTOR, RHEB, NF2, NRAS, HRAS). Pts received GSK2636771 400mg/day (28-days cycles). RECIST 1.1 overall response rate (ORR) was the primary endpoint.
Results: Of 59 enrolled pts, 56 were eligible and received treatment. Of 22 pts with PTEN mut/del (Arm N: 6 uterine, 2 breast, 2 prostate, 2 head/neck ca, 10 other), all are off treatment as of analysis (14 disease progression, 4 for adverse events [AEs], 4 other). One pt (4.5%) with prostate ca (PTEN deletion, MPRSS2-ERG fusion) attained a partial response (-42%). Of 7 (32%) pts with stable disease (SD), 2 had SD \u3e 6 months (uterine leiomyosarcoma; endometrial carcinoma). Of 34 pts with loss of PTEN protein by IHC (Arm P: 7 prostate, 6 breast, 3 squamous anal ca, 2 cholangiocarcinoma, 16 other), all are off treatment as of analysis (26 disease progression, 4 for AE, 4 other). Of 9 (37.5%) pts with SD, 3 had SD \u3e 6 months (prostate cancer; squamous bladder cancer, squamous anal cancer). Median progression-free survival was 1.8 months for both arms. Gr ≥ 3 treatment-related (tr) reversible toxicities were experienced by 30% (7) and 20% (7) of pts in arms N and P, respectively. No tr Gr 5 toxicities were observed in either arm.
Conclusions: Single agent GSK2636771 has very modest activity in ca with PTEN gene mutation/deletion and/or PTEN protein loss
From DNA barcodes to monitoring of amphipod communities: status and relevance of curation and annotation of DNA sequence data
Size Segregation of Granular Matter in Silo Discharges
We present an experimental study of segregation of granular matter in a
quasi-two dimensional silo emptying out of an orifice. Size separation is
observed when multi-sized particles are used with the larger particles found in
the center of the silo in the region of fastest flow. We use imaging to study
the flow inside the silo and quantitatively measure the concentration profiles
of bi-disperse beads as a function of position and time. The angle of the
surface is given by the angle of repose of the particles, and the flow occurs
in a few layers only near the top of this inclined surface. The flowing region
becomes deeper near the center of the silo and is confined to a parabolic
region centered at the orifice which is approximately described by the
kinematic model. The experimental evidence suggests that the segregation occurs
on the surface and not in the flow deep inside the silo where velocity
gradients also are present. We report the time development of the
concentrations of the bi-disperse particles as a function of size ratios, flow
rate, and the ratio of initial mixture. The qualitative aspects of the observed
phenomena may be explained by a void filling model of segregation.Comment: 6 pages, 10 figures (gif format), postscript version at
http://physics.clarku.edu/~akudrolli/nls.htm
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Audio Cartography: Visual Encoding of Acoustic Parameters
Our sonic environment is the matter of subject in multiple domains which developed individual means of its description. As a result, it lacks an established visual language through which knowledge can be connected and insights shared. We provide a visual communication framework for the systematic and coherent documentation of sound in large-scale environments. This consists of visual encodings and mappings of acoustic parameters into distinct graphic variables that present plausible solutions for the visualization of sound. These candidate encodings are assembled into an application-independent, multifunctional, and extensible design guide. We apply the guidelines and show example maps that acts as a basis for the exploration of audio cartography
2008-2009 President\u27s Report
The Linfield College President\u27s Annual Report is a collection of information about the year in review, including academics, student life and athletics, enrollment, finances, philanthropy, and leadership
On noise treatment in radio measurements of cosmic ray air showers
Precise measurements of the radio emission by cosmic ray air showers require
an adequate treatment of noise. Unlike to usual experiments in particle
physics, where noise always adds to the signal, radio noise can in principle
decrease or increase the signal if it interferes by chance destructively or
constructively. Consequently, noise cannot simply be subtracted from the
signal, and its influence on amplitude and time measurement of radio pulses
must be studied with care. First, noise has to be determined consistently with
the definition of the radio signal which typically is the maximum field
strength of the radio pulse. Second, the average impact of noise on radio pulse
measurements at individual antennas is studied for LOPES. It is shown that a
correct treatment of noise is especially important at low signal-to-noise
ratios: noise can be the dominant source of uncertainty for pulse height and
time measurements, and it can systematically flatten the slope of lateral
distributions. The presented method can also be transfered to other experiments
in radio and acoustic detection of cosmic rays and neutrinos.Comment: 4 pages, 6 figures, submitted to NIM A, Proceedings of ARENA 2010,
Nantes, Franc
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