QUADRICEPS FEMORIS ANGLE OF ELITE AND NON-ELITE ATHLETES IN OLYMPIC STYLE WEIGHTLIFTING

OBJECTIVE: To find out the quadriceps femoris angle (Q-angle) values of elite and non-elite athletes in Olympic style weightlifting. METHODS: This study included 22 male elite athletes that won medals in international Olympic style weightlifting championships and 22 male non-elite athletes who won medals in national Olympic style weightlifting championships. A goniometer was used to determine the angle of the quadriceps femoris muscle while the athletes were in supine position and the muscle was inactivated.  Anthropometric measurements of right-left thigh and lower leg length, right-left thigh and calf girth, and pelvic width of athletes were obtained. One repetition maximum of snatch, clean and jerk and leg strength of the athletes was recorded. To study demographic characteristics and some anthropometric values of lower extremity of the athletes, t-Test was conducted for independent groups. To compare anthropometric measurements of right-left lower extremity and right-left Q-angle values, paired sample t-Test was used. Right-left Q-angle values and relations among other variables were studied by Pearson correlation analysis. SPSS was used for all analyses. RESULTS: Mean age was 19.73±2.97 years and 18.73±1.55 years for of elite and non-elite athletes respectively. No significant difference was observed in demographic characteristics and in some anthropometric values of lower extremity of elite and non-elite athletes (p>0.05). However, right-left Q-angle values of non-elite athletes (10.14±1.55o and 10.14±1.52o, respectively) were higher than the right-left Q-angle values of elite athletes (8.32±1.39o and 8.32±1.32o, respectively) [p<0.003]. CONCLUSIONS: Olympic style weightlifting, which is maintained in elite level, affects the quadriceps femoris angle

COVID-19 in pediatric nephrology centers in Turkey

Background/aim: There is limited data on COVID-19 disease in children with kidney disease. We aimed to investigate the characteristics and prognosis of COVID-19 in pediatric nephrology patients in Turkey. Materials and methods: This was a national, multicenter, retrospective cohort study based on an online survey evaluating the data between 11th March 2020 and 11th March 2021 as an initial step of a detailed pediatric nephrology COVID-19 registry. Results: Two hundred and three patients (89 girls and 114 boys) were diagnosed with COVID-19. One-third of these patients (36.9%) were between 10–15 years old. Half of the patients were on kidney replacement therapy: kidney transplant (KTx) recipients (n = 56, 27.5%), patients receiving chronic hemodialysis (n = 33, 16.3%) and those on peritoneal dialysis (PD) (n = 18, 8.9%). Fifty-four (26.6%) children were asymptomatic. Eighty-two (40.3%) patients were hospitalized and 23 (28%) needed intensive care unit admission. Fifty-five percent of the patients were not treated, while the remaining was given favipiravir (20.7%), steroid (16.3%), and hydroxychloroquine (11.3%). Acute kidney injury developed in 19.5% of hospitalized patients. Five (2.4%) had MIS-C. Eighty-three percent of the patients were discharged without any apparent sequelae, while 7 (3.4%) died. One hundred and eight health care staff were infected during the study period. Conclusion: COVID-19 was most commonly seen in patients who underwent KTx and received HD. The combined immunosuppressive therapy and frequent exposure to the hospital setting may increase these patients’ susceptibility. Staff infections before vaccination era were alarming, various precautions should be taken for infection control, particularly optimal vaccination coverage

Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study

Summary Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20 [1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality. Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030

Evaluation of a series of patients operated for adhesive intestinal obstructions

The risk of bowel obstruction after laparotomy in infants and children, especially in developing countries, has not been well researched. Objectives: The aim of this study was to perform a detailed analysis of adhesions and the risk factors for adhesion-associated intestinal obstruction after laparotomy in children. Methods: This retrospective study involved patients who were operated between January 1990 and January 2001 on for postoperative adhesive intestinal obstruction (AIO). Results: During a 11-year period, a total of 45 patients aged 6 days to 14 years (mean 7.75 years) were operated on after 1341 laparotomies. The incidence of AIO was 3.35%. Six (13.3%) patients were urgently operated on while 29 (64.4%) patients were operated on in the first 3 days. The patients were operated on at 6th postoperative day at the earliest and at 10 years at the latest. Each of two children with midgut volvulus (relative risk 50%) and jejunal atresia (relative risk 27.7%) were operated on twice. The mortality and morbidity rates were found to be 2.2% (1 patient) and 22.2%, respectively. AIO was most commonly observed after operations involving the pelvic area (77.7%). Appendectomy, trauma, invagination, and megacolon surgeries were the most common postoperative causes of AIO. Conclusion: This study showed that adhesions in children occurred more commonly after lower abdominal surgery. The risks were closely related to the site and type of the first surgery. Although the risk of having adhesions was very high in the first years, it also persists in the following years

Effects of acute taurine consumption on single bout of muscular endurance resistance exercise performance and recovery in resistance trained young male adults

Study aim: This study investigated the effect of taurine supplementation on exercise performance and recovery from resistance exercise. The study was conducted with a cross-over design in a double-blind manner

Multicenter Evaluation of Patients with Cutaneous Malignant Melanoma in Turkey: MELAS Study

WOS: 000319980200095PubMed: 23534790Background: Malignant melanoma is a cancer that demonstrates rapid progression and atypical clinically features with a poor prognosis. Aim: This study was performed to determine the clinical characteristics and treatment outcomes of patients with malignant melanoma in Turkey. Methods: The medical records of 98 patients between 2007-2012 at our centers were retrieved from the patient registry. Overall survival (OS) was calculated using the Kaplan-Meier method. Results: In our study, with the median follow-up of all patients with cutaneous MM of 46.3 months, the median OS rate of all cases was 43.6 months and 5-year OS was 48.6%. However, five-year OS rates of patients with localized disease (stage I-II) and node involvement (stage III) were 60.3% and 39.6%, respectively. The median OS of stage IV patients was 8.7 months and 1-year OS rate was 26.2%. We showed that advanced stage, male gender, and advanced age in all patients with MM were significant prognostic factors of OS. Conclusions: Compared with the results of current studies from Western countries, we found similar findings concerning demographical features, histological variables and survival analyses for our patients with cutaneous MM in Turkey

Recurrent Sertoli-Leydig cell tumor of ovary in 8-year-old girl

Sertoli-Leydig cell tumors are rare sex cord-stromal neoplasms that account for <0.2% of ovarian tumors. These tumors with a retiform pattern pose difficult diagnostic problems, with the majority of being misinterpreted as serous papillary cystadenocarcinoma and endodermal sinus tumor. We report an 8-year-old female patient presented to our institution with a huge mass and pain in the lower abdomen and recurrence in the 10th months following the first operation. Only four cases of Sertoli-Leydig cell tumors have been reported under age of the eight years in the literature so far. It is difficult to define the stage and the morphology of Sertoli-Leydig cell tumors with retiform pattern in children and chemotherapy or radiotherapy administration is contraversial. However, fertility sparing surgeries should be considered as a first treatment choice on the time of the diagnosis and the recurrence