Coping styles and emotional states in patients with chronic kidney insufficiency (CRI)

El afrontamiento es definido como aquellas estrategias que tiene el paciente para minimizar el impacto negativo causado por la enfermedad y a su vez las alteraciones emocionales que afectan su bienestar psicológico y su entorno familiar y social. Objetivo: Contrastar el desarrollo de estudios referentes a estilos de afrontamiento y los estados emocionales en personas con insuficiencia renal crónica. Método: Se emplearon bases de datos como REDALYC, SCIELO, SCIENCEDIREC, Repositorios Universitarios, abordando publicaciones entre los años 2011 a 2019, los criterios de búsqueda fueron “afrontamiento”, “estilos de afrontamiento”, “estados emocionales”, afrontamiento e Insuficiencia renal” “insuficiencia renal crónica”. Los instrumentos usados para la sistematización fue la Matriz Bibliográfica, mientras que, para la codificación y análisis de la información se hizo uso del Software de análisis cualitativo Atlas ti. Resultados: Los artículos analizados muestran mayor tendencia de estudio en el área clínica y de la salud. En cuanto a los referentes teóricos, Lazarus y Folkman presentan mayor tendencia frente al afrontamiento y Daniel Goleman frente a la inteligencia emocional; en relación con preferencias metodológicas, el enfoque cuantitativo sobresale de otros enfoques investigativos. De acuerdo a los instrumentos más utilizados prima la entrevista semiestructurada, inventario de estrategias de afrontamiento (CSI) y el Inventario de Inteligencia Emocional (EQ-i). Conclusión: Se puede inferir que, los estilos de afrontamiento y estados emocionales en la población con IRC no han conseguido un amplio margen de estudios y representan un amplio margen de estudio para la labor del Profesional en Psicología.Introduction: Coping is defined as those strategies that the patient has to minimize the negative impact caused by the disease and in turn the emotional alterations that affect their psychological well-being and their family and social environment. Objective: To contrast the development of studies concerning coping styles and emotional states in people with CKD, Method: Databases such as REDALYC, SCIELO, SCIENCEDIREC, University Repositories were used, addressing publications between the years 2011 to 2019, the search criteria were “coping”, “coping styles”, “emotional states”, coping and “renal insufficiency” “chronic renal failure”. The instruments used for systematization were the Bibliographic Matrix, while the qualitative analysis software Atlas Ti was used for coding and analysis of the information. Results: The articles analyzed show a greater tendency to study in the clinical and health area. Regarding theoretical references, Lazarus and Folkman show a greater tendency towards coping and Daniel Goleman towards emotional intelligence; in relation to methodological preferences, the quantitative approach stands out from other research approaches. According to the most used instruments, the semi-structured interview, the Coping Strategies Inventory (CSI) and the Emotional Intelligence Inventory (EQ-i) are the most used. In conclusion, it can be inferred that coping styles and emotional states in the population with CKD have not achieved a wide margin of studies and represent a wide margin of study for the work of the Psychology Professional

Estilos de afrontamiento y estados emocionales en pacientes con insuficiencia renal crónica (IRC)

El afrontamiento es definido como aquellas estrategias que tiene el paciente para minimizar el impacto negativo causado por la enfermedad y a su vez las alteraciones emocionales que afectan su bienestar psicológico y su entorno familiar y social. Objetivo: Contrastar el desarrollo de estudios referentes a estilos de afrontamiento y los estados emocionales en personas con insuficiencia renal crónica

Nuevos sensores SERS basados en sustratos de silicato cálcico hidratado irradiados por láser

XVI Congreso Nacional de Materiales, Ciudad Real, España, 28-1 julio 2022.--https://cnmat2022.comEl hormigón y los morteros de cemento están presentes en monumentos y edificaciones declarados Patrimonio de la Humanidad por la UNESCO. Estos pueden contener aditivos orgánicos, en concentraciones menores al 5%, que afectan a la hidratación del cemento modificando sus propiedades reológicas como la fluidez y la velocidad de fraguado, pudiendo en ocasiones favorecer la precipitación de sales expansivas. Para la correcta restauración y conservación de estos ¿nuevos¿ materiales del patrimonio de base cemento, resulta indispensable conocer todos sus componentes, con el fin de determinar cuáles pueden influir o producir su deterioro y así determinar el tipo de tratamientos protectores compatibles. Sin embargo, los componentes que se encuentran en bajas concentraciones son difíciles de detectar. La espectroscopía Raman intensificada por superficie (Surface-Enhanced Raman Spectroscopy, SERS) se ha convertido en una técnica de identificación molecular de gran utilidad en el campo del Patrimonio Cultural. Esto es debido su alta sensibilidad, proporcionada por el efecto físico conocido como localización de plasmones superficiales de superficie, el cual ocurre cuando la molécula se encuentra en estrecho contacto con nanoestructuras metálicas y se usa una radiación láser resonante para estas nanoestructuras. Una de las consecuencias de este efecto es la gigantesca intensificación de la emisión Raman (hasta en 6 órdenes de magnitud) que permite la detección de moléculas orgánicas a muy bajas concentraciones. En este trabajo se presenta una primera aproximación de la fabricación de un nuevo sensor SERS ¿in situ¿ basado en el principal producto de la hidratación del cemento Pórtland, un silicato cálcico hidratado. Para ello se sintetizaron geles C-S-H con y sin Ag que se modificaron estructuralmente por ablación con láser UV y visible. Los resultados del análisis SERS, utilizando la rodamina B como molécula orgánica modelo, sobre sustratos de silicato cálcico hidratado con y sin Ag, procesados por láser mostraron una elevada amplificación de la señal Raman de la rodamina en disolución acuosa con una concentración de 10-6 M, en comparación con los mismos sustratos sin tratamiento láser

Development of new SERS sensors based on the laser irradiation of the major hydration product of Portland Cement

13th International Conference on Lasers in the Conservation of Artworks, Florence ­ September 12­-16, 2022Portland cement concrete is considered, since being adopted by modern architecture in the twentieth century, a `noble¿ material, the latest to join the list of built heritage materials. For correct conservation of cement concrete, including the selection of compatible protective treatments, the determination of constitutents that can influence, cause or be the result of deterioration phenomena is of fundamental importance. However, components found in low concentrations, such as organic aditives, are difficult to detect with the most common concrete research­ and industry­driven analysis. In heritage science, surface­ enhanced Raman spectroscopy(SERS) has become a very useful molecular identification technique for the detection of organic molecules at very low concentrations provided by the physical effect known as surface plasmon localization. This effect occurs when the molecule is in close contact with metallic nanostructures upon resonant laser irradiation. In this work, the first approach for the development of a new "in situ" SERS sensor for Portland cement concrete is presented using a simplified system based on the main product of the hydration of Portland cement, a calcium silicate hydrate (C­S­H). Thereby, C­S­H with and without Ag were synthesized and irradiated by nanosecond ultraviolet and visible laser pulses for the detection of a model organic molecule, rhodamine B in low concentration (10­-6 M), a traditional analyte in SERS studies. The results of SERS analysis showed a high amplification of the rhodamine Raman signal in substrates irradiated by laser.The financial support of this work has been provided by the SCOCHLAS project (Study and Conservation of Cultural Heritage with Lasers, PID2019­104124RB­100) and the H2020 project IPERION HS (Integrated Platform for the European Research Infrastructure ON Heritage Science, GA 871034). The professional support provided by the CSIC 'Open Heritage: Research and Society (PTI­PAIS)' Interdisciplinary Thematic Platform is also gratefully acknowledge

Risk of cancer in family members of patients with lynch-like syndrome

Lynch syndrome (LS) is a common cause of hereditary colorectal cancer (CRC). Some CRC patients develop mismatch repair deficiency without germline pathogenic mutation, known as Lynch-like syndrome (LLS). We compared the risk of CRC in first-degree relatives (FDRs) in LLS and LS patients. LLS was diagnosed when tumors showed immunohistochemical loss of MSH2, MSH6, and PMS2; or loss of MLH1 with BRAF wild type; and/or no MLH1 methylation and absence of pathogenic mutation in these genes. CRC and other LS-related neoplasms were followed in patients diagnosed with LS and LLS and among their FDRs. Standardized incidence ratios (SIRs) were calculated for CRC and other neoplasms associated with LS among FDRs of LS and LLS patients. In total, 205 LS (1205 FDRs) and 131 LLS families (698 FDRs) had complete pedigrees. FDRs of patients with LLS had a high incidence of CRC (SIR, 2.08; 95% confidence interval (CI), 1.56–2.71), which was significantly lower than that in FDRs of patients with LS (SIR, 4.25; 95% CI, 3.67–4.90; p < 0.001). The risk of developing other neoplasms associated with LS also increased among FDR of LLS patients (SIR, 2.04; 95% CI, 1.44–2.80) but was lower than that among FDR of patients with LS (SIR, 5.01, 95% CI, 4.26–5.84; p < 0.001). FDRs with LLS have an increased risk of developing CRC as well as LS-related neoplasms, although this risk is lower than that of families with LS. Thus, their management should take into account this increased risk

Risk of cancer in family members of patients with lynch-like syndrome

Lynch syndrome (LS) is a common cause of hereditary colorectal cancer (CRC). Some CRC patients develop mismatch repair deficiency without germline pathogenic mutation, known as Lynch-like syndrome (LLS). We compared the risk of CRC in first-degree relatives (FDRs) in LLS and LS patients. LLS was diagnosed when tumors showed immunohistochemical loss of MSH2, MSH6, and PMS2; or loss of MLH1 with BRAF wild type; and/or no MLH1 methylation and absence of pathogenic mutation in these genes. CRC and other LS-related neoplasms were followed in patients diagnosed with LS and LLS and among their FDRs. Standardized incidence ratios (SIRs) were calculated for CRC and other neoplasms associated with LS among FDRs of LS and LLS patients. In total, 205 LS (1205 FDRs) and 131 LLS families (698 FDRs) had complete pedigrees. FDRs of patients with LLS had a high incidence of CRC (SIR, 2.08; 95% confidence interval (CI), 1.56–2.71), which was significantly lower than that in FDRs of patients with LS (SIR, 4.25; 95% CI, 3.67–4.90; p < 0.001). The risk of developing other neoplasms associated with LS also increased among FDR of LLS patients (SIR, 2.04; 95% CI, 1.44–2.80) but was lower than that among FDR of patients with LS (SIR, 5.01, 95% CI, 4.26–5.84; p < 0.001). FDRs with LLS have an increased risk of developing CRC as well as LS-related neoplasms, although this risk is lower than that of families with LS. Thus, their management should take into account this increased risk