Artritis reumatoide canina : a propósito de un caso

En el presente trabajo se analiza un caso de artritis reumatoide canina, mostrando las diferentes pruebas efectuadas para su diagnóstico, los tratamientos utilizados y los resultados obtenidos tras la aplicación de los mismos. En todas las 'revisiones, se realizaban de forma sistemática estudios radiográficos de las articulaciones afectadas, análisis sanguíneo que incluía la realización del proteinograma y estudio del líquido sinovial, lo que permitió seguir puntualmente la evolución del proceso. Tras el sacrificio del animal se efectuaron los exámenes anatomopatológicos de las articulaciones lesionadas, confirmando el diagnóstico clínico previo de artritis reumatoide canina.The present study shows a case of canine rheumatoid arhritis. Different systems of diagnosis carried out, treatment applied, and results at short and lonq-term are reviewed. In every re-examination a complete hemogram, including proteinogram, and a synovial fluid analysis were carried out, moreover radiographs of affected joints were taken. This systematic procedure allows us to know the evolution after every treatment. After patient euthanasia, pathologic lesions of affected joints were analyzed and the clinic diagnosis of rheumatoid arthritis was corroborated

Acceptability and feasibility of a virtual community of practice to primary care professionals regarding patient empowerment : A qualitative pilot study

Background: Virtual communities of practice (vCoPs) facilitate online learning via the exchange of experiences and knowledge between interested participants. Compared to other communities, vCoPs need to overcome technological structures and specific barriers. Our objective was to pilot the acceptability and feasibility of a vCoP aimed at improving the attitudes of primary care professionals to the empowerment of patients with chronic conditions. Methods: We used a qualitative approach based on 2 focus groups: one composed of 6 general practitioners and the other of 6 practice nurses. Discussion guidelines on the topics to be investigated were provided to the moderator. Sessions were audio-recorded and transcribed verbatim. Thematic analysis was performed using the ATLAS-ti software. Results: The available operating systems and browsers and the lack of suitable spaces and time were reported as the main difficulties with the vCoP. The vCoP was perceived to be a flexible learning mode that provided up-to-date resources applicable to routine practice and offered a space for the exchange of experiences and approaches. Conclusions: The results from this pilot study show that the vCoP was considered useful for learning how to empower patients. However, while vCoPs have the potential to facilitate learning and as shown create professional awareness regarding patient empowerment, attention needs to be paid to technological and access issues and the time demands on professionals. We collected relevant inputs to improve the features, content and educational methods to be included in further vCoP implementation. Trial registration: ClinicalTrials.gov, NCT02757781. Registered on 25 April 2016

Spread of a SARS-CoV-2 variant through Europe in the summer of 2020.

Following its emergence in late 2019, the spread of SARS-CoV-21,2 has been tracked by phylogenetic analysis of viral genome sequences in unprecedented detail3–5. Although the virus spread globally in early 2020 before borders closed, intercontinental travel has since been greatly reduced. However, travel within Europe resumed in the summer of 2020. Here we report on a SARS-CoV-2 variant, 20E (EU1), that was identified in Spain in early summer 2020 and subsequently spread across Europe. We find no evidence that this variant has increased transmissibility, but instead demonstrate how rising incidence in Spain, resumption of travel, and lack of effective screening and containment may explain the variant’s success. Despite travel restrictions, we estimate that 20E (EU1) was introduced hundreds of times to European countries by summertime travellers, which is likely to have undermined local efforts to minimize infection with SARS-CoV-2. Our results illustrate how a variant can rapidly become dominant even in the absence of a substantial transmission advantage in favourable epidemiological settings. Genomic surveillance is critical for understanding how travel can affect transmission of SARS-CoV-2, and thus for informing future containment strategies as travel resumes. © 2021, The Author(s), under exclusive licence to Springer Nature Limited

CARB-ES-19 Multicenter Study of Carbapenemase-Producing Klebsiella pneumoniae and Escherichia coli From All Spanish Provinces Reveals Interregional Spread of High-Risk Clones Such as ST307/OXA-48 and ST512/KPC-3

ObjectivesCARB-ES-19 is a comprehensive, multicenter, nationwide study integrating whole-genome sequencing (WGS) in the surveillance of carbapenemase-producing K. pneumoniae (CP-Kpn) and E. coli (CP-Eco) to determine their incidence, geographical distribution, phylogeny, and resistance mechanisms in Spain.MethodsIn total, 71 hospitals, representing all 50 Spanish provinces, collected the first 10 isolates per hospital (February to May 2019); CPE isolates were first identified according to EUCAST (meropenem MIC > 0.12 mg/L with immunochromatography, colorimetric tests, carbapenem inactivation, or carbapenem hydrolysis with MALDI-TOF). Prevalence and incidence were calculated according to population denominators. Antibiotic susceptibility testing was performed using the microdilution method (EUCAST). All 403 isolates collected were sequenced for high-resolution single-nucleotide polymorphism (SNP) typing, core genome multilocus sequence typing (cgMLST), and resistome analysis.ResultsIn total, 377 (93.5%) CP-Kpn and 26 (6.5%) CP-Eco isolates were collected from 62 (87.3%) hospitals in 46 (92%) provinces. CP-Kpn was more prevalent in the blood (5.8%, 50/853) than in the urine (1.4%, 201/14,464). The cumulative incidence for both CP-Kpn and CP-Eco was 0.05 per 100 admitted patients. The main carbapenemase genes identified in CP-Kpn were blaOXA–48 (263/377), blaKPC–3 (62/377), blaVIM–1 (28/377), and blaNDM–1 (12/377). All isolates were susceptible to at least two antibiotics. Interregional dissemination of eight high-risk CP-Kpn clones was detected, mainly ST307/OXA-48 (16.4%), ST11/OXA-48 (16.4%), and ST512-ST258/KPC (13.8%). ST512/KPC and ST15/OXA-48 were the most frequent bacteremia-causative clones. The average number of acquired resistance genes was higher in CP-Kpn (7.9) than in CP-Eco (5.5).ConclusionThis study serves as a first step toward WGS integration in the surveillance of carbapenemase-producing Enterobacterales in Spain. We detected important epidemiological changes, including increased CP-Kpn and CP-Eco prevalence and incidence compared to previous studies, wide interregional dissemination, and increased dissemination of high-risk clones, such as ST307/OXA-48 and ST512/KPC-3

Aspectos que conforman la identidad profesional del profesorado de formación y orientación laboral

La identidad profesional nos define frente a otros y nos sitúa junto al colectivo. Planteamos el objetivo de estudiar los elementos que conforman la identidad profesional en el profesorado de la especialidad de Formación y Orientación Laboral. Durante diez meses se realizó en Galicia un estudio enmarcado en una investigación cualitativa, mediante una perspectiva teórico-metodológica fenomenológica, en la que participaron 43 personas. Realizamos entrevistas en profundidad, grupo de discusión y cuaderno de campo, agrupando los resultados en tres temas: vocación, formación y mundo laboral. La inquietud por acciones formativas y profesionales forjó identidades relacionadas con gratificaciones laborales concordantes al desarrollo de etapas laborales. La heterogeneidad del colectivo y las reformas educativas facilitan que la identidad profesional sea dispersa

Aspectos que conforman la identidad profesional del profesorado de formación y orientación laboral

La identidad profesional nos define frente a otros y nos sitúa junto al colectivo. Planteamos el objetivo de estudiar los elementos que conforman la identidad profesional en el profesorado de la especialidad de Formación y Orientación Laboral. Durante diez meses se realizó en Galicia un estudio enmarcado en una investigación cualitativa, mediante una perspectiva teórico-metodológica fenomenológica, en la que participaron 43 personas. Realizamos entrevistas en profundidad, grupo de discusión y cuaderno de campo, agrupando los resultados en tres temas: vocación, formación y mundo laboral. La inquietud por acciones formativas y profesionales forjó identidades relacionadas con gratificaciones laborales concordantes al desarrollo de etapas laborales. La heterogeneidad del colectivo y las reformas educativas facilitan que la identidad profesional sea dispersa

Expanded use of a fast photography technique to characterize laser-induced plasma plumes

Expanded use of fast photography is proposed to characterize laser ablation plasma plumes by the analysis of a set of photographs by means of appropriate mathematical algorithms. The laser ablation plasma plumes studied were generated by ablation of both a multicomponent target of the nominal composition Ni50Mn37Sn13 and a highly pure Cu target (Cu) using a Q-switched Nd-YAG laser system:The experiments were conducted under different background argon pressures. Several photograph parameters such as intensity per unit time of exposure for a pixel, mean intensity per pixel per unit time of exposure, integrated intensity and cross correlation were studied. The intensity per unit time of exposure allowed for identification of the fast component of the triple structure of the expanding plasma into the background gas (that travels at a speed close to the one measured in vacuum). This parameter together with the use of cross correlation enabled the identification of regions of the expanded plasma plume with higher and lower similarities in their optical emission behavior. The mean intensity per pixel per unit time of exposure can be used as a measurement of the amount of light emitted by the plume as a function of time