Kink stability, propagation, and length scale competition in the periodically modulated sine-Gordon equation

We have examined the dynamical behavior of the kink solutions of the one-dimensional sine-Gordon equation in the presence of a spatially periodic parametric perturbation. Our study clarifies and extends the currently available knowledge on this and related nonlinear problems in four directions. First, we present the results of a numerical simulation program which are not compatible with the existence of a radiative threshold, predicted by earlier calculations. Second, we carry out a perturbative calculation which helps interpret those previous predictions, enabling us to understand in depth our numerical results. Third, we apply the collective coordinate formalism to this system and demonstrate numerically that it accurately reproduces the observed kink dynamics. Fourth, we report on a novel occurrence of length scale competition in this system and show how it can be understood by means of linear stability analysis. Finally, we conclude by summarizing the general physical framework that arises from our study.Comment: 19 pages, REVTeX 3.0, 24 figures available from A S o

Cosmic acceleration: Inhomogeneity versus vacuum energy

In this essay, I present an alternative explanation for the cosmic acceleration which appears as a consequence of recent high redshift Supernova data. In the usual interpretation, this cosmic acceleration is explained by the presence of a positive cosmological constant or vacuum energy, in the background of Friedmann models. Instead, I will consider a Local Rotational Symmetric (LRS) inhomogeneous spacetime, with a barotropic equation of state for the cosmic matter. Within this framework the kinematical acceleration of the cosmic fluid or, equivalently, the inhomogeneity of matter, is just the responsible of the SNe Ia measured cosmic acceleration. Although in our model the Cosmological Principle is relaxed, it maintains local isotropy about our worldline in agreement with the CBR experiments.Comment: LATEX, 7 pags, no figs, Honorable Mention in the 1999 Essay Competition of the Gravity Research Foundatio

Na/K pump regulation of cardiac repolarization: Insights from a systems biology approach

The sodium-potassium pump is widely recognized as the principal mechanism for active ion transport across the cellular membrane of cardiac tissue, being responsible for the creation and maintenance of the transarcolemmal sodium and potassium gradients, crucial for cardiac cell electrophysiology. Importantly, sodium-potassium pump activity is impaired in a number of major diseased conditions, including ischemia and heart failure. However, its subtle ways of action on cardiac electrophysiology, both directly through its electrogenic nature and indirectly via the regulation of cell homeostasis, make it hard to predict the electrophysiological consequences of reduced sodium-potassium pump activity in cardiac repolarization. In this review, we discuss how recent studies adopting the Systems Biology approach, through the integration of experimental and modeling methodologies, have identified the sodium-potassium pump as one of the most\ud important ionic mechanisms in regulating key properties of cardiac repolarization and its rate-dependence, from subcellular to whole organ levels. These include the role of the pump in the biphasic modulation of cellular repolarization and refractoriness, the rate control of intracellular sodium and calcium dynamics and therefore of the adaptation of repolarization to changes in heart rate, as well as its importance in regulating pro-arrhythmic substrates through modulation of dispersion of repolarization and restitution. Theoretical findings are consistent across a variety of cell types and species including human, and widely in agreement with experimental findings. The novel insights and hypotheses on the role of the pump in cardiac electrophysiology obtained through this integrative approach could eventually lead to novel therapeutic and diagnostic strategies

Breathers in inhomogeneous nonlinear lattices: an analysis via centre manifold reduction

We consider an infinite chain of particles linearly coupled to their nearest neighbours and subject to an anharmonic local potential. The chain is assumed weakly inhomogeneous. We look for small amplitude discrete breathers. The problem is reformulated as a nonautonomous recurrence in a space of time-periodic functions, where the dynamics is considered along the discrete spatial coordinate. We show that small amplitude oscillations are determined by finite-dimensional nonautonomous mappings, whose dimension depends on the solutions frequency. We consider the case of two-dimensional reduced mappings, which occurs for frequencies close to the edges of the phonon band. For an homogeneous chain, the reduced map is autonomous and reversible, and bifurcations of reversible homoclinics or heteroclinic solutions are found for appropriate parameter values. These orbits correspond respectively to discrete breathers, or dark breathers superposed on a spatially extended standing wave. Breather existence is shown in some cases for any value of the coupling constant, which generalizes an existence result obtained by MacKay and Aubry at small coupling. For an inhomogeneous chain the study of the nonautonomous reduced map is in general far more involved. For the principal part of the reduced recurrence, using the assumption of weak inhomogeneity, we show that homoclinics to 0 exist when the image of the unstable manifold under a linear transformation intersects the stable manifold. This provides a geometrical understanding of tangent bifurcations of discrete breathers. The case of a mass impurity is studied in detail, and our geometrical analysis is successfully compared with direct numerical simulations

Magnetic-field asymmetry of nonlinear mesoscopic transport

We investigate departures of the Onsager relations in the nonlinear regime of electronic transport through mesoscopic systems. We show that the nonlinear current--voltage characteristic is not an even function of the magnetic field due only to the magnetic-field dependence of the screening potential within the conductor. We illustrate this result for two types of conductors: A quantum Hall bar with an antidot and a chaotic cavity connected to quantum point contacts. For the chaotic cavity we obtain through random matrix theory an asymmetry in the fluctuations of the nonlinear conductance that vanishes rapidly with the size of the contacts.Comment: 4 pages, 2 figures. Published versio

The second Feng-Rao number for codes coming from telescopic semigroups

In this manuscript we show that the second Feng-Rao number of any telescopic numerical semigroup agrees with the multiplicity of the semigroup. To achieve this result we first study the behavior of Ap\'ery sets under gluings of numerical semigroups. These results provide a bound for the second Hamming weight of one-point Algebraic Geometry codes, which improves upon other estimates such as the Griesmer Order Bound

Imperfect Imitation Can Enhance Cooperation

The promotion of cooperation on spatial lattices is an important issue in evolutionary game theory. This effect clearly depends on the update rule: it diminishes with stochastic imitative rules whereas it increases with unconditional imitation. To study the transition between both regimes, we propose a new evolutionary rule, which stochastically combines unconditional imitation with another imitative rule. We find that, surprinsingly, in many social dilemmas this rule yields higher cooperative levels than any of the two original ones. This nontrivial effect occurs because the basic rules induce a separation of timescales in the microscopic processes at cluster interfaces. The result is robust in the space of 2x2 symmetric games, on regular lattices and on scale-free networks.Comment: 4 pages, 4 figure