María Jesús Vitón, Diálogos con Raquel. Praxis pedagógicas y reflexión de saberes para el desarrollo educativo en la diversidad cultural, Editorial Popular, Madrid, España, 2012, 211 p.

María Jesús Vitón es Doctora en Ciencias de la Educación y Profesora Titular de la Universidad Autónoma de Madrid. Desarrolla su docencia y sus investigaciones en el terreno de lo socio-educativo, en grupos, en territorios, en países y en paisajes donde su quehacer profesional cobra el sentido de contribuir a transformar; a transformar con otros. Diálogos con Raquel es una propuesta metodológica práctica para planificar, desarrollar y evaluar acciones educativas en la diversidad cultural, con..

Microbiota composition and intestinal integrity remain unaltered after the inclusion of hydrolysed Nannochloropsis gaditana in Sparus aurata diet

The use of lysed microalgae in the diet of carnivorous fish can increase the bioavailability of proteins and bioactive compounds, such as unsaturated fatty acids or vitamins in the digestive tract. These are essential molecules for the proper physiological development of fish in aquaculture. However, some antinutritional components and other undesirable molecules can be released from an excess of microalgae supplied, compromising the integrity of the intestine. The inclusion of small amounts of hydrolized microalgae in the fish diet can be a good strategy to avoid negative effects, improving the availability of beneficial compounds. Nannochloropsis gaditana is an interesting microalgae as it contains nutraceuticals. Previous studies reported beneficial effects after its inclusion in the diet of Sparus aurata, a widely cultured species in Europe and in all Mediterranean countries. However, administration of raw microalgae can produce intestinal inflammation, increased intestinal permeability, bacterial translocation and disturbance of digestion and absorption processes

Healthcare workers hospitalized due to COVID-19 have no higher risk of death than general population. Data from the Spanish SEMI-COVID-19 Registry

Aim To determine whether healthcare workers (HCW) hospitalized in Spain due to COVID-19 have a worse prognosis than non-healthcare workers (NHCW). Methods Observational cohort study based on the SEMI-COVID-19 Registry, a nationwide registry that collects sociodemographic, clinical, laboratory, and treatment data on patients hospitalised with COVID-19 in Spain. Patients aged 20-65 years were selected. A multivariate logistic regression model was performed to identify factors associated with mortality. Results As of 22 May 2020, 4393 patients were included, of whom 419 (9.5%) were HCW. Median (interquartile range) age of HCW was 52 (15) years and 62.4% were women. Prevalence of comorbidities and severe radiological findings upon admission were less frequent in HCW. There were no difference in need of respiratory support and admission to intensive care unit, but occurrence of sepsis and in-hospital mortality was lower in HCW (1.7% vs. 3.9%; p = 0.024 and 0.7% vs. 4.8%; p<0.001 respectively). Age, male sex and comorbidity, were independently associated with higher in-hospital mortality and healthcare working with lower mortality (OR 0.211, 95%CI 0.067-0.667, p = 0.008). 30-days survival was higher in HCW (0.968 vs. 0.851 p<0.001). Conclusions Hospitalized COVID-19 HCW had fewer comorbidities and a better prognosis than NHCW. Our results suggest that professional exposure to COVID-19 in HCW does not carry more clinical severity nor mortality

Deus

A relação entre a arte e a transcendência é imemorial. Uma sociedade interroga-se sobre a vida e a morte, desenvolve rituais e estabelece mediações através da oferta de objetos, de sacrifícios, de representações, de práticas funerárias, de comportamentos que não surgem da necessidade biológica, surgem da necessidade pensada, ou melhor, surgem do espírito. A questão estabelece-se entre o pensamento e as coisas. As coisas, o seu destino, o seu processo, o seu devir, têm regularidades, e irregularidades. Sobre as regularidades, como a quantidade, a permanência, a repetição, podemos estabelecer representações, ou relações de conhecimento. Sobre as irregularidades, percebidas como arbitrárias, que provocam incerteza, vida e morte, destinos indeterminados, podemos pensar uma determinação exterior, que nos transcende na duração e no conhecimento. Ao lançar “Deus” como tema deste número da revista Estúdio teve-se a perceção inteira da sua profundidade. A condição humana faz-se da representação da sua finitude, na mesma medida da grandeza do que a transcende. Assim foi, neste número, o tema do desafio lançado pela Estúdio. Adicionou-se este tema ao escopo que a revista Estúdio sempre tem apresentado, e que a distingue, ao solicitar aos artistas e criadores que apresentem as suas perspetivas sobre as obras de seus companheiros de profissão, colocando um ênfase no estudo de artistas que são menos conhecidos, e dando prioridade aos originários dos países abrangidos pelos idiomas da revista, português e espanhol. Este número 10 da Estúdio, dedicado ao tema Deus, é constituído por 19 artigos, selecionados a partir de 46 submissões, a que se adicionou um dossier editorial, perfazendo assim um total de 21 artigos e 1 entrevista.info:eu-repo/semantics/publishedVersio

Association Between Preexisting Versus Newly Identified Atrial Fibrillation and Outcomes of Patients With Acute Pulmonary Embolism

Background Atrial fibrillation (AF) may exist before or occur early in the course of pulmonary embolism (PE). We determined the PE outcomes based on the presence and timing of AF. Methods and Results Using the data from a multicenter PE registry, we identified 3 groups: (1) those with preexisting AF, (2) patients with new AF within 2 days from acute PE (incident AF), and (3) patients without AF. We assessed the 90-day and 1-year risk of mortality and stroke in patients with AF, compared with those without AF (reference group). Among 16 497 patients with PE, 792 had preexisting AF. These patients had increased odds of 90-day all-cause (odds ratio [OR], 2.81; 95% CI, 2.33-3.38) and PE-related mortality (OR, 2.38; 95% CI, 1.37-4.14) and increased 1-year hazard for ischemic stroke (hazard ratio, 5.48; 95% CI, 3.10-9.69) compared with those without AF. After multivariable adjustment, preexisting AF was associated with significantly increased odds of all-cause mortality (OR, 1.91; 95% CI, 1.57-2.32) but not PE-related mortality (OR, 1.50; 95% CI, 0.85-2.66). Among 16 497 patients with PE, 445 developed new incident AF within 2 days of acute PE. Incident AF was associated with increased odds of 90-day all-cause (OR, 2.28; 95% CI, 1.75-2.97) and PE-related (OR, 3.64; 95% CI, 2.01-6.59) mortality but not stroke. Findings were similar in multivariable analyses. Conclusions In patients with acute symptomatic PE, both preexisting AF and incident AF predict adverse clinical outcomes. The type of adverse outcomes may differ depending on the timing of AF onset.info:eu-repo/semantics/publishedVersio

Multiancestry analysis of the HLA locus in Alzheimer’s and Parkinson’s diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04 subtypes

Across multiancestry groups, we analyzed Human Leukocyte Antigen (HLA) associations in over 176,000 individuals with Parkinson’s disease (PD) and Alzheimer’s disease (AD) versus controls. We demonstrate that the two diseases share the same protective association at the HLA locus. HLA-specific fine-mapping showed that hierarchical protective effects of HLA-DRB1*04 subtypes best accounted for the association, strongest with HLA-DRB1*04:04 and HLA-DRB1*04:07, and intermediary with HLA-DRB1*04:01 and HLA-DRB1*04:03. The same signal was associated with decreased neurofibrillary tangles in postmortem brains and was associated with reduced tau levels in cerebrospinal fluid and to a lower extent with increased Aβ42. Protective HLA-DRB1*04 subtypes strongly bound the aggregation-prone tau PHF6 sequence, however only when acetylated at a lysine (K311), a common posttranslational modification central to tau aggregation. An HLA-DRB1*04-mediated adaptive immune response decreases PD and AD risks, potentially by acting against tau, offering the possibility of therapeutic avenues

Juicio a los prejuicios

Fecha de edición aproximada, 1994Unidad didáctica de educación en valores, educación moral y educación cívica. Su objetivo es contribuir a la sensibilización frente a los problemas del racismo generados por la creciente inmigración de personas procedentes de países con menos recursos. Pretende promover un acercamiento entre nuestra cultura y la de los países de orígen de los inmigrantes como forma de superar tópicos, prejuicios y desarrollar actitudes y valores en favor del pluralismo cultural y el respeto mutuo. Las actividades planteadas tienen el objetivo de desmontar los prejuicios colectivos existentes y promover actitudes solidarias.AragónBiblioteca de Educación del Ministerio de Educación, Cultura y Deporte; Calle San Agustín, 5; 28014 Madrid; Tel. +34917748000; [email protected]