Spatial wave intensity correlations in quasi-one-dimensional wires

Spatial intensity correlations between waves transmitted through random media are analyzed within the framework of the random matrix theory of transport. Assuming that the statistical distribution of transfer matrices is isotropic, we found that the spatial correlation function can be expressed as the sum of three terms, with distinctive spatial dependences. This result coincides with the one obtained in the diffusive regime from perturbative calculations, but holds all the way from quasi-ballistic transport to localization. While correlations are positive in the diffusive regime, we predict a transition to negative correlations as the length of the system decreases.Comment: 10 pages, 3 figures. Submitted to Physical Review Letter

Electric and magnetic dipolar response of Germanium spheres: Interference effects, scattering anisotropy and optical forces

We address the scattering cross sections, and their consequences, for submicrometer Germanium spheres. It is shown that there is a wide window in the near infrared where light scattering by these particles is fully described by their induced electric and magnetic dipoles. In this way, we observe remarkable anisotropic scattering angular distributions, as well as zero forward or backward scattered intensities, which until recently was theoretically demonstrated only for hypothetically postulated magnetodielectric spheres. Also, interesting new effects of the optical forces exerted on these objects are now obtained.Comment: 13 pages, 4 figure

Hypothesis testing with active information

We develop hypothesis testing for active information -the averaged quantity in the Kullback-Liebler divergence. To our knowledge, this is the first paper to derive exact probabilities of type-I errors for hypothesis testing in the area.Comment: Typo changed in one of the names in the Metadata, and a reference to an equation from the paper in the Supplemen

Practical solvent-free microwave-assisted hydroboration of alkynes

A simple and rapid protocol for the anti-Markovnikov hydroboration of alkynes assisted by microwave irradiation has been developed. Pinacolborane smoothly reacts with terminal alkynes to obtain (E)-alkenyl boronates in good yields and short reactions times in the absence of solvent. Further transformations on the carbon-boron bond of the adducts can be sequentially achieved without the need of purifying the alkenyl boronates

Enantioselective Copper-Catalyzed Synthesis of Trifluoromethyl-Cyclopropylboronates

A copper-catalyzed enantioselective cyclopropanation involving trifluorodiazoethane in the presence of alkenyl boronates has been developed. This transformation enables the preparation of 2-substituted-3-(trifluoromethyl)cyclopropylboronates with high levels of stereocontrol. The products are valuable synthetic intermediates by transformation of the boronate group. This methodology can be applied to the synthesis of novel trifluoromethylated analogues of trans-2-arylcyclopropylamines, which are prevalent motifs in biologically active compounds

Synthesis and Photophysical Behavior of a Highly FluorescentFamily of Unsymmetrical Organoboron Complexes Containing5‑(Pyridin-2-ylmethylene)imidazolidine-2,4-dione Moieties

A new and highly fluorescent family of unsymmetrical organoboron complexes containing 5-(pyridin-2-ylmethylene)imidazolidine-2,4-dione moieties has been synthesized in three steps. These compounds show strong absorptions covering a wide range of the UV-Vis spectrum and are strongly emissive (ff of up to 0.92 in CH3CN). Moreover, two fluorophores that include an alkyne or an azide group at the end of the alkyl chain, and with potential utility in bioorthogonal chemistry, have been developed. One of these, in which the glycol substituent provides an enhanced water solubility without compromising the fluorescence (ff = 0.85 in water), may be of particular importance

Safety, feasibility, and hemodynamic response of regadenoson for stress perfusion CMR

Owing to its pharmacodynamics and posology, the use of regadenoson for stress cardiac magnetic resonance (CMR) has potential advantages over other vasodilators. We sought to evaluate the safety, hemodynamic response and diagnostic performance of regadenoson stress-CMR in routine clinical practice. All regadenoson stress-CMR examinations performed between May 2017 and July 2020 at our institution were retrospectively reviewed. A total of 698 studies were included for the final analysis. A conventional stress/rest protocol was performed using a 1.5T MRI scanner (Magnetom Aera, Siemens Healthineers, Erlangen, Germany). Adverse events, clinical symptoms, and hemodynamic response were assessed. Diagnostic accuracy of the test was evaluated in patients who underwent invasive coronary angiography. Nearly half of patients (48.5%) remained asymptomatic. Most common clinical symptoms included dyspnea (137, 19.6%), chest pain (116, 16.6%) and flushing (44, 6.3%). Two patients (0.28%) could not complete the examination due to severe hypotension or unbearable chest pain. Overall, an increase in heart rate (HR) response (36.2% [IQR: 22.5–50.9]) and a decrease in systolic and diastolic blood pressure (BP) (median systolic BP response of -5% [IQR: -11.5-0.6]; median diastolic BP response of -6.3 mmHg [IQR: -13.4-0]) was observed. Patients with symptoms induced by regadenoson showed higher HR response (40.3%, IQR: 26.4–56.1 vs. 32.4%, IQR: 19-45.6, p<0.001), whereas a blunted HR response was observed in diabetic (29.6%, IQR: 18.4–42 p<0.001), obese (31.7%, IQR: 20.7–46.2 p=0.005) and patients aged 70 years or older (32.9%, IQR: 22.6–43.1 p<0.001). Overall, regadenoson stress-CMR showed 95.65% (IQ 91.49–99.81) sensitivity, 54.84% (IQ 35.71–73.97) specificity, 86.99% (IQ 82.74–94.68) positive predictive value, and 77.27% (IQ 57.49–97.06) negative predictive value for detecting significant coronary stenosis as compared with invasive coronary angiography. Regadenoson is a well-tolerated vasodilator that can be safely employed for stress perfusion CMR, with high diagnostic performanc

Simulaciones climáticas con modelos regionales: sensibilidad a la elección de parametrizaciones

Ponencia presentada en: V Congreso Internacional de la Asociación Española de Climatología celebrado en Zaragoza del 18 al 21 de septiembre de 2006.[ES]Los modelos regionales de clima presentan una serie de características que se dejan a la elección del usuario. Entre ellas, la selección de las parametrizaciones físicas más adecuadas para la zona a estudio o la resolución espacial a la que se desea realizar la simulación. La elección de unas u otras opciones determina el resultado de la simulación. El presente estudio analiza el impacto que tiene la selección de parametrizaciones en los resultados de un experimento anidado en los Reanálisis de NCEP/NCAR y centrado sobre la Península Ibérica. El estudio se centra en el ciclo anual de precipitación y temperatura superficial.[EN]The regional climate models present a series of features to be decided by the user. Among them, the selection of the physical parameterizations more appropriate for the target area or the spatial resolution to perform the regional simulation. The selection of one or another option determines the resulting simulation. The present study analizes the impact of the selection of different parameterizations in the results of an experiment nested into the NCEP/NCAR Reanalysis and centered over the Iberian Peninsula. The study focuses on the seasonal cycle of precipitation and surface temperature.Este trabajo ha sido financiado por los proyectos RAMSHES (REN2002-04584-C04/CLI) de la Comisión Interministerial de Ciencia y Tecnología, INVENTO (CGL2005-06966- C07/CLI) y SPECT (CGL2005-06097/CLI) del Ministerio de Educación y Ciencia y 9/UPV00060.310-15343/2003 de la Universidad de País Vasco. J. Fernández agradece al Departamento de Educación, Universidades e Investigación del Gobierno Vasco la beca postdoctoral BFI04.52. J.F. González-Rouco está financiado por el programa Ramón y Cajal del Ministerio de Educación y Ciencia

Propuesta de la Sociedad Española de Farmacia Comunitaria (SEFAC) sobre servicios profesionales farmacéuticos en farmacia comunitaria

Con el presente documento SEFAC ofrece un planteamiento sobre los servicios profesionales farmacéuticos (SPF) a implantar y desarrollar por las farmacias comunitarias en los próximos años justificando la misión y el papel del farmacéutico en su prestación, partiendo de la realidad que supone el hecho de que la farmacia comunitaria constituye uno de los mayores recursos asistenciales de atención primaria, que diariamente presta, además de la dispensación, otras actividades sanitarias profesionales centradas en el paciente y en la población que son susceptibles de constituir otros servicios farmacéuticos, y que existen nuevas necesidades relacionadas con el uso de los medicamentos que generan una morbimortalidad evitable en la población. Este planteamiento tiene como objetivo impulsar la prestación de los SPF desde la farmacia comunitaria con el fin de cubrir las necesidades relacionadas con la atención de los pacientes que utilizan medicamentos y con la salud pública. Para lograr este objetivo se definen términos esenciales como servicios profesionales farmacéuticos, catálogo y cartera de servicios farmacéuticos, se indican las características que deben cumplir estos servicios plasmándolas en un decálogo, se propone una clasificación de los tipos de SPF y se enumeran las premisas necesarias para lograr su implantación. Las características de los servicios incluyen sus especificaciones, la capacitación y certificación, calidad, retribución, financiación y difusión, estableciendo el papel de SEFAC en la formación, capacitación, certificación de los profesionales directamente o en colaboración con otras sociedades científicas, y en la certificación y programas de supervisión externa de los SPF de aquellas farmacias que lo requieran

EFECTOS DE UN PROGRAMA DE BIODANZA EN RELACIÓN A PARÁMETROS FÍSICOS Y PSICOLÓGICOS EN EDUCACIÓN PRIMARIA [Effects of a biodanza program in relation to physical and psychological parameters in Primary Education]

Introducción: El objetivo del estudio fue conocer los efectos físicos y psicológicos de un programa de biodanza en niños de Educación Primaria. Metodología: La muestra estuvo compuesta por 53 niños y niñas de un colegio público de la provincia de Huelva a los que se dividió en un grupo cuasi-control y otro cuasi-experimental. A todos los participantes se les aplicaron cuestionarios, al comienzo y al final del curso, para medir las variables psicológicas (autoestima, inteligencia emocional y satisfacción con la vida); y test físicos para medir el consumo máximo de oxígeno y la agilidad. Resultados: Los resultados muestran mejoras significas en las variables autoestima (t(53)=4.599; p< .001), inteligencia emocional (t(52)=2.160; p= .035) y agilidad (U=-3.763; p< .001). Para las variables consumo máximo de oxígeno y satisfacción con la vida se han encontrado mejoras, pero no suficiente como para considerarse significativas. Conclusiones: Estos resultados sugieren que un programa de biodanza en jóvenes escolares puede ser una buena herramienta para mejorar las variables físicas y psicológicas mencionadas anteriormente.   Abstract Introduction: The aim of the study was to know the physical and psychological effects of a biodanza program in primary school children. Methods: Fifty-three students (boys and girls) from a public school located in the province of Huelva were selected for the sample. The students were divided into two different groups: a quasi-control group and a quasi-experimental one. Questionnaires were applied to all the participants at the beginning and at the end of the course in order to measure the psychological variables (self-esteem, emotional inteligence and life satisfaction). Several physical test was also applied to measure maximum consumption of oxygen and agility. Results: Results show significant improvement in self-esteem (t(53)=4.599; p< .001), emotional inteligence (t(52)=2.160; p= .035) and agility (U=-3.763; p< .001). For maximum consumption of oxygen and life satisfaction variables some improvements have been found, but they are not enough to be considered significant. Conclusions: These results suggest that a biodanza program in school children can be a good tool to improve the physical and psychological variables previously cited