Reduced Lean Mass in Early Alzheimer Disease and Its Association With Brain Atrophy

This is the published version. Copyright American Medical AssociationObjective: To examine body composition in individuals with early AD and without dementia and its relation to cognition and brain volume. Design: Cross-sectional case-control study. Participants: Individuals without dementia (Clinical Dementia Rating, 0; n=70) and with early-stage AD (Clinical Dementia Rating, 0.5 or 1; n=70) in the Alzheimer and Memory Program at the University of Kansas School of Medicine. Main Outcome Measures: Participants were evaluated with brain magnetic resonance imaging (MRI), neuropsychological testing, and dual-energy x-ray absorptiometry to determine whole-body fat and lean masses. Body mass index was calculated as weight in kilograms divided by height in meters squared. Results: Lean mass was reduced in persons with early AD compared with controls without dementia (F=7.73; P=.006) after controlling for sex. Whole-brain volume (=.20; P.001), white matter volume (=.19; P.001), and global cognitive performance (=.12; P=.007) were associated with lean mass (dependent variable) when controlling for age and sex. The total body fat and percentage of body fat values were not different across groups or related to cognition and brain volume. Conclusion: Loss of lean mass is accelerated in AD and is associated with brain atrophy and cognitive performance, perhaps as a direct or indirect consequence of AD pathophysiology or through shared mechanisms common to both AD and sarcopenia

Lincoln Memorial Commission report : message from the President of the United States transmitting a report of the Lincoln Memorial Commission, and its recommendations, upon the location, plan, and design for a memorial, in the city of Washington, to the memory of Abraham Lincoln, in accordance with the act approved February 9, 1911

This pamphlet outlines the Lincoln Memorial Commission Report . A brief description is given below the title on the cover, and this description reads: Message from the President of the United States. Transmitting a report of the Lincoln memorial Commission, and its recommendations, upon the location, plan, and design for a memorial, in the city of Washington, to the memory of Abraham Lincoln, in Accordance with the act approved February 9, 1911. (Senate document / 62d Congress, 3d session ; no. 965) December 5, 1912. Referred to the Committee on the Library and ordered to be printed, with illustrations. William H. Taft, chairman. Includes appendixes containing reports of the Commission of Fine Arts, and architects Henry Bacon and John Russell Pope.https://scholarsjunction.msstate.edu/fvw-pamphlets/2029/thumbnail.jp

Flamingo Vol. III N 2

Anonymous. Cover. Picture. 0. Anonymous. Untitled. Picture. 4. Price, John M. Dada--Esthetic Nihilism. Prose. 5. G.C. Tolerance. Poem. 6. G.W.B. The Castaway. Poem. 6. G.W.B. Cinquains. Poem. 7. Holt, K. HORATI CARMINA, Liber I, ix. Prose. 7. W.A.V. Untitled. Poem. 7. A.E.R. Moods. Poem. 7. G.W.B. Some Say The Moon. Poem. 7. A.E.R. On Quoting The Night Has A Thousand Eyes . Poem. 7. Anonymous. Chapel Cherubs. Prose. 8. E.B. Untitled. Picture. 8. E.B. Untitled. Picture. 8. Anonymous. Untitled. Prose. 9. Anonymous. Untitled. Prose. 9. Anonymous. FLIP— MIGHT I ASK YOU FOR THIS DANCE? FLAP— PLEASE DO, I\u27VE BEEN DYING TO REFUSE YOU ALL EVENING. . Picture. 9. Anonymous. HUSBAND (SAVAGELY)— MARIA, WHERE\u27S MY CLOTHES? MARIA— GOOD HEAVENS, DEAR, I WONDER IF I USED THEM IN THE SALAD. Picture. 9. Anonymous. Our Log Table. Prose. 9. Anonymous. Approved Vocabulary For Fans. Prose. 9. Anonymous. Untitled. Prose. 9.; Anonymous. Untitled. Prose. 9. Anonymous. Untitled. Prose. 9. Anonymous. Untitled. Prose. 9. Anonymous. Only Too True! Prose. 10. F.T. GEORGE TOLD ME ALL THE SECRETS OF HIS PAST LAST NIGHT. REALLY! WHAT DID YOU THINK OF THEM? OH, I THOUGHT THEY WERE HORRIBLY DISAPPOINTING. Picture. 10. Anonymous. Untitled. Prose. 10. Anonymous. Untitled. Prose. 10. Anonymous. Untitled. Prose. 10. Howard, Lillis. The Engaged Homo. Poem. 10. Anonymous. Before and After. Poem. 11. Anonymous. Untitled. Poem. 11. Ubersax. AS OTHERS MIGHT SEE US—CLEVELAND HALL TO A CUBIST. Picture. 11. Anonymous. Untitled. Prose. 11. Anonymous. Untitled. Prose. 11. Anonymous. Untitled. Prose. 11. Anonymous. SECOND FROM THE RIGHT— WHAT\u27S THAT DESERTED OLD BUILDING OVER THERE? DITTO LEFT— MUST BE WHERE THEY USED TO MAKE HAIRPINS. Picture. 11. Anonymous. Untitled. Prose. 11. Anonymous. Untitled. Prose. 11. E.T.B. Broadway Bizarre. Prose. 12. E.B. Untitled. Picture. 13. E.B. The First One. Picture. 13. Anonymous. It\u27s done. Prose. 14. W.G.M. Mother. Prose. 15. Anonymous. Our Daily Mud. Prose. 15. G.C. Optimism. Poem. 15. Bridge. Denison Comics. Picture. 16. Anonymous. Our Asinetic Appreciation Corner. Prose. 18. Anonymous. STILL LIFE OF A NEAR-BEER AT THE TURNING POINT. Picture. 18. Rine, Russell. Stewed and Hashed. Poem. 18. Anonymous. Untitled. Poem. 18. Anonymous. Untitled. Poem. 19. Anonymous. Untitled. Prose. 19. Anonymous. Untitled. Prose. 19. Mercer, Hod. OUR OWN IDEA OF SOMETHING AESTHETIC. Picture. 19. Anonymous. Untitled. Prose. 19. Anonymous. Untitled. Prose. 19. Anonymous. Such Is Life. Poem. 19. Anonymous. Untitled. Prose. 19. Anonymous. Untitled. Prose. 19. Grayce. THE FLIGHT IS ON—THE FESTIVAL IS HERE. Picture. 20. W.G.K. Eutopia Regained. Prose. 20. Anonymous. Untitled. Prose. 20. Anonymous. Untitled. Prose. 20. Anonymous. Oh You Nine Weeks. Poem. 20. Anonymous. Untitled. Prose. 20. Anonymous. Untitled. Prose. 20. Anonymous. Untitled. Prose. 20. Anonymous. THAT MAUSOLEUM HAS BEEN CONDEMNED BY THE BUILDING INSPECTOR. WHAT\u27S WRONG WITH IT? IT HASN\u27T ANY FIRE ESCAPES. Picture. 20. Jester. Untitled. Prose. 24. Anonymous. Untitled. Prose. 24. Panther. Untitled. Prose. 24. Octopus. Untitled. Prose. 24. Mugwump. Untitled. Prose. 24. Reel, Virginia. Untitled. Prose. 24. Garber, Jock. Kows and Why Not. Prose. 25. Texas Scalper. Untitled. Prose. 25. Lord Jeff. Untitled. Prose. 28. Lampoon. Cut Rates. Prose. 28. Malteaser. Untitled. Prose. 28. Sun Dodger. Untitled. Prose. 28. Beanpot. Untitled. Prose. 28. Malteaser. Untitled. Prose. 28. Gargoyle. Putting It Fairly. Prose. 29. Malteaser. Untitled. Prose. 29. Gargoyle. Untitled. Prose. 29. Sun Dial. Untitled. Prose. 29. Gargoyle. Untitled. Prose. 30. Malteaser. Untitled. Prose. 30. Panther. Untitled. Prose. 30. Sun Dial. The Stuffed Kind. Prose. 30. Student Life. Untitled. Prose. 30. Malteaser. Heard in EC. Class. Prose. 30. Nashville Tennessean. Untitled. Prose. 30. Lemon Punch. Untitled. Prose. 31. Sun Dial. Untitled. Prose. 31. Gargoyle. Two is a Crowd. Prose. 31. Phoenix. Untitled. Prose. 31

Transplantation of Ciliary Neurotrophic Factor-Expressing Adult Oligodendrocyte Precursor Cells Promotes Remyelination and Functional Recovery after SpinalCord Injury

Demyelination contributes to the dysfunction after traumatic spinal cord injury (SCI). We explored whether the combination of neurotrophic factors and transplantation of adult rat spinal cord oligodendrocyte precursor cells (OPCs) could enhance remyelination and functional recovery after SCI. Ciliary neurotrophic factor (CNTF) was the most effective neurotrophic factor to promote oligodendrocyte (OL) differentiation and survival of OPCs in vitro. OPCs were infected with retroviruses expressing enhanced green fluorescent protein (EGFP) or CNTF and transplanted into the contused adult thoracic spinal cord 9 d after injury. Seven weeks after transplantation, the grafted OPCs survived and integrated into the injured spinal cord. The survival of grafted CNTF-OPCs increased fourfold compared with EGFP-OPCs. The grafted OPCs differentiated into adenomatus polyposis coli (APC+) OLs, and CNTF significantly increased the percentage of APC+ OLs from grafted OPCs. Immunofluorescent and immunoelectron microscopic analyses showed that the grafted OPCs formed central myelin sheaths around the axons in the injured spinal cord. The number of OL-remyelinated axons in ventrolateral funiculus (VLF) or lateral funiculus (LF) at the injured epicenter was significantly increased in animals that received CNTF-OPC grafts compared with all other groups. Importantly, 75% of rats receiving CNTF-OPC grafts recovered transcranial magnetic motor-evoked potential and magnetic interenlargement reflex responses, indicating that conduction through the demyelinated axons in VLF or LF, respectively, was partially restored. More importantly, recovery of hindlimb locomotor function was significantly enhanced in animals receiving grafts of CNTF-OPCs. Thus, combined treatment with OPC grafts expressing CNTF can enhance remyelination and facilitate functional recovery after traumatic SCI

Bostonia: The Boston University Alumni Magazine. Volume 10

Founded in 1900, Bostonia magazine is Boston University's main alumni publication, which covers alumni and student life, as well as university activities, events, and programs

Capturing Saddam Hussein: How the full story got away, and what conflict journalism can learn from it

The capture of Saddam Hussein in December 2003 was reported with a sense of triumph which must have greatly satisfied the United States forces occupying Iraq. This was the victory they had been looking for; the seminal moment which signalled that the invasion had been a success. But the reporting of that event was also a missed opportunity: an example of incomplete story telling. In this article, I use my personal experience of reporting on the event for the BBC as a starting point to examine what it, and the way it was covered, tell us about the omissions which are frequently a feature of conflict reporting. The article argues that the way in which reporters had to work in Iraq then meant that they did not convey all of the event’s wider implications, and suggests how that might be improved

Pennsylvania Folklife Vol. 29, No. 3

• Shuler Family Correspondence • Vestiges of the Markley Family • 30 Years of the Kutztown Folk Festival: A Photo Essay • The Rural Village • Father of the Fraternity: Christopher Schlegel and Rosicrucianism • A Lexical Comparison of Two Sister Languages: Pennsylvania German and Yiddish • Aldes un Neieshttps://digitalcommons.ursinus.edu/pafolklifemag/1087/thumbnail.jp

Exploiting Laboratory and Heliophysics Plasma Synergies

Recent advances in space-based heliospheric observations, laboratory experimentation, and plasma simulation codes are creating an exciting new cross-disciplinary opportunity for understanding fast energy release and transport mechanisms in heliophysics and laboratory plasma dynamics, which had not been previously accessible. This article provides an overview of some new observational, experimental, and computational assets, and discusses current and near-term activities towards exploitation of synergies involving those assets. This overview does not claim to be comprehensive, but instead covers mainly activities closely associated with the authors’ interests and reearch. Heliospheric observations reviewed include the Sun Earth Connection Coronal and Heliospheric Investigation (SECCHI) on the National Aeronautics and Space Administration (NASA) Solar Terrestrial Relations Observatory (STEREO) mission, the first instrument to provide remote sensing imagery observations with spatial continuity extending from the Sun to the Earth, and the Extreme-ultraviolet Imaging Spectrometer (EIS) on the Japanese Hinode spacecraft that is measuring spectroscopically physical parameters of the solar atmosphere towards obtaining plasma temperatures, densities, and mass motions. The Solar Dynamics Observatory (SDO) and the upcoming Solar Orbiter with the Heliospheric Imager (SoloHI) on-board will also be discussed. Laboratory plasma experiments surveyed include the line-tied magnetic reconnection experiments at University of Wisconsin (relevant to coronal heating magnetic flux tube observations and simulations), and a dynamo facility under construction there; the Space Plasma Simulation Chamber at the Naval Research Laboratory that currently produces plasmas scalable to ionospheric and magnetospheric conditions and in the future also will be suited to study the physics of the solar corona; the Versatile Toroidal Facility at the Massachusetts Institute of Technology that provides direct experimental observation of reconnection dynamics; and the Swarthmore Spheromak Experiment, which provides well-diagnosed data on three-dimensional (3D) null-point magnetic reconnection that is also applicable to solar active regions embedded in pre-existing coronal fields. New computer capabilities highlighted include: HYPERION, a fully compressible 3D magnetohydrodynamics (MHD) code with radiation transport and thermal conduction; ORBIT-RF, a 4D Monte-Carlo code for the study of wave interactions with fast ions embedded in background MHD plasmas; the 3D implicit multi-fluid MHD spectral element code, HiFi; and, the 3D Hall MHD code VooDoo. Research synergies for these new tools are primarily in the areas of magnetic reconnection, plasma charged particle acceleration, plasma wave propagation and turbulence in a diverging magnetic field, plasma atomic processes, and magnetic dynamo behavior.United States. Office of Naval ResearchNaval Research Laboratory (U.S.

The Wide-field Infrared Survey Explorer (WISE): Mission Description and Initial On-orbit Performance

The all sky surveys done by the Palomar Observatory Schmidt, the European Southern Observatory Schmidt, and the United Kingdom Schmidt, the InfraRed Astronomical Satellite and the 2 Micron All Sky Survey have proven to be extremely useful tools for astronomy with value that lasts for decades. The Wide-field Infrared Survey Explorer is mapping the whole sky following its launch on 14 December 2009. WISE began surveying the sky on 14 Jan 2010 and completed its first full coverage of the sky on July 17. The survey will continue to cover the sky a second time until the cryogen is exhausted (anticipated in November 2010). WISE is achieving 5 sigma point source sensitivities better than 0.08, 0.11, 1 and 6 mJy in unconfused regions on the ecliptic in bands centered at wavelengths of 3.4, 4.6, 12 and 22 microns. Sensitivity improves toward the ecliptic poles due to denser coverage and lower zodiacal background. The angular resolution is 6.1, 6.4, 6.5 and 12.0 arc-seconds at 3.4, 4.6, 12 and 22 microns, and the astrometric precision for high SNR sources is better than 0.15 arc-seconds.Comment: 22 pages with 19 included figures. Updated to better match the accepted version in the A