Screening Reproductive-Stage Cold Tolerance For The NSW Rice Improvement Program

A summary of this work is provided. The rest of the report will subsequently be the basis for information contained in a thesis to be produced by John Smith, Masters student. This project aimed at developing a clearly-defined and repeatable low-temperature screening protocol to enable selection for cold tolerance in the NSW DPI Rice Improvement Program. The series of trials identified a number of important issues that must be addressed when measuring tolerance to low temperatures during the reproductive stage of rice. The capacity of the controlled-environment glasshouse to maintain the temperatures necessary to induce floret sterility is extremely important, as small deviations from both maximum and minimum temperatures can influence floret sterility. The controlled-temperature facility used at Deniliquin had limited capacity to maintain low temperatures during periods of high ambient minimum temperatures. The glasshouse in which plants are raised before and after cold treatment must also have good temperature control so that cold damage is not induced during these periods. Factors other than temperature also influence floret sterility, and this project demonstrated an effect of the position of the pot within the glasshouse, as well as an effect associated with plants were completely surrounded by others or at the edge of the plant canopy ..

The dual endothelin converting enzyme/neutral endopeptidase inhibitor SLV-306 (daglutril), inhibits systemic conversion of big endothelin-1 in humans

Aims - Inhibition of neutral endopeptidases (NEP) results in a beneficial increase in plasma concentrations of natriuretic peptides such as ANP. However NEP inhibitors were ineffective anti-hypertensives, probably because NEP also degrades vasoconstrictor peptides, including endothelin-1 (ET-1). Dual NEP and endothelin converting enzyme (ECE) inhibition may be more useful. The aim of the study was to determine whether SLV-306 (daglutril), a combined ECE/NEP inhibitor, reduced the systemic conversion of big ET-1 to the mature peptide. Secondly, to determine whether plasma ANP levels were increased. Main methods - Following oral administration of three increasing doses of SLV-306 (to reach an average target concentration of 75, 300, 1200 ng ml− 1 of the active metabolite KC-12615), in a randomised, double blinded regime, big ET-1 was infused into thirteen healthy male volunteers. Big ET-1 was administered at a rate of 8 and 12 pmol kg− 1 min− 1 (20 min each). Plasma samples were collected pre, during and post big ET-1 infusion. ET-1, C-terminal fragment (CTF), big ET-1, and atrial natriuretic peptide (ANP) were measured. Key findings - At the two highest concentrations tested, SLV-306 dose dependently attenuated the rise in blood pressure after big ET-1 infusion. There was a significant increase in circulating big ET-1 levels, compared with placebo, indicating that SLV-306 was inhibiting an increasing proportion of endogenous ECE activity. Plasma ANP concentrations also significantly increased, consistent with systemic NEP inhibition. Significance - SLV-306 leads to inhibition of both NEP and ECE in humans. Simultaneous augmentation of ANP and inhibition of ET-1 production is of potential therapeutic benefit in cardiovascular disease

Global Rice Atlas: Disaggregated seasonal crop calendar and production

Purpose: Rice is an important staple crop cultivated in more than 163 million ha globally. Although information on the distribution of global rice production is available by country and, at times, at subnational level, information on its distribution within a year is often lacking in different rice growing regions. Knowing when and where rice is planted and harvested and the associated production is crucial to policy and decision making on food security. To examine seasonal and geographic variations in food supply, we developed a detailed rice crop calendar and linked it with disaggregated production data. Approach and methods used: We compiled from various sources detailed data on rice production, and planting and harvesting dates by growing season. To standardize the production data to the same period, we adjusted the production values so that the totals for each country will be the same as those of FAO for 2010-2012. We then linked data on rice production with the corresponding crop calendar information to estimate production at harvest time by month then we calculated totals for each country and region. Key results: The bulk of global annual harvests of rice is from September to November, corresponding with the harvest of the wet season rice in Asia and Africa. Total rough rice production during those peak months exceed 381 million tons, which account for about half of annual global rice output. Production is lowest in January with only 11 million tons in total. Regional production is lowest in Asia in January, Americas in December, Africa in July and rest of the world in May. Synthesis and Applications: A globally complete and spatially detailed rice crop calendar is important to crop growth simulation modelling and assessment of vulnerability of rice areas to biotic and abiotic stresses. Linked to production estimates, it can be used in analyzing spatial and seasonal production trends to better assess and predict price fluctuations , and to mitigate potential significant shortfalls in food production at certain times of the year

Operation of Alcator C-Mod with high-Z plasma facing components and implications

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Pergumulan as the starter and sustainer of Servant Leadership A case of academic leadership in a private University in Indonesia

In the disruptive era, every organization is expected to cope with change. This includes the ones in the sector of higher education. Servant leadership is considered as the leadership approach that enables Higher Educational Institutions (HEIs) to deal with the inevitable changes. This research explores an academic leadership in a private university in Indonesia, which endorses servant leadership as its leadership approach. The case study involves the interview of twenty-six academic leaders who have asked to answer two fundamental questions: 1) How do they perceive the invitation to lead as an academic leader and 2) What did they do as they consider whether to take the offer to lead as an academic leader? The gathered data was processed using the Qualitative Data Analysis consisting data condensation, data display and drawing and verifying conclusion. Twenty-five academic leaders said no when they first offer and this initial refusal drives the researcher to find a term called �pergumulan� as the common theme across the interviewees. �Pergumulan� or a spiritual struggle happened during the pre-leadership journey and during the leadership journey of these academic leaders. The former suggests that �pergumulan� is spiritual, intrapersonal and interpersonal. The latter indicates that pergumulan happens when the servant leaders search their motivation and figure out the way to improve themselves while serving their followers. Lastly, during their leadership, the servant leaders are also having the �pergumulan� as they have to confront or rebuke their followers

A Putative Leucine-Rich Repeat Receptor Kinase Involved in Brassinosteroid Signal Transduction

AbstractBrassinosteroids are a class of growth-promoting regulators that play a key role throughout plant development. Despite their importance, nothing is known of the mechanism of action of these steroid hormones. We describe the identification of 18 Arabidopsis dwarf mutants that are unable to respond to exogenously added brassinosteroid, a phenotype that might be expected for brassinosteroid signaling mutants. All 18 mutations define alleles of a single previously described gene, BRI1. We cloned BRI1 and examined its expression pattern. It encodes a ubiquitously expressed putative receptor kinase. The extracellular domain contains 25 tandem leucine-rich repeats that resemble repeats found in animal hormone receptors, plant disease resistance genes, and genes involved in unknown signaling pathways controlling plant development