1,986 research outputs found

    Managing Innovation Search and Select in Disrupting Environments

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    This thesis explores how organisations manage new product development (NPD) focused innovation across a portfolio of core, adjacent and breakthrough environments. The study focuses on the search and select phases of the innovation process, and how incumbents identify and validate a range of opportunities. Organisations face the paradox of how to establish search and select routines for focal markets, while also setting up routines to sense and respond to disruptive innovation signals from adjacent and more peripheral environments. The study builds on research into peripheral vision, and considers how organisations operationalise innovation search and select in disrupting environments. To analyse how organisations manage search and select in turbulent environments, the author conducted research in the disrupting higher education (HE) publishing industry using qualitative research methods. The study focused on ten case companies, and the researcher conducted 61 interviews with 63 individuals over a six month period across ten companies publishing 9,000 out of the world’s 32,000 academic journals. The interviewees ranged from CEOs and CTOs to production, operations, editorial, publishing, sales and marketing directors and managers. The analysis revealed 11 search and select capabilities that need to be in place to manage NPD effectively in HE publishing. The research identified five contextual factors that influence how search and select is operationalised in disrupting environments. A framework is proposed to enable the mapping of individual opportunities within a wider NPD portfolio. The project identified ten key market insight areas where firms in the HE publishing sector need to focus. The findings have implications for practice, especially for HE publishers, online media companies, and business to business service organisations. Further research is proposed into how the cognitive frames of boards and senior teams affect the structure and operationalisation of NPD portfolios; how visual media companies search for, develop (ideate) and select programme and film projects in the disrupting media sector; and how workflow mapping and the identification of jobs-to-be-done is deployed within the NPD process in different settings

    Flamingo Vol. III N 1

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    E.B. Cover. Picture. 0. Anonymous. Untitled. Prose. 5. Anonymous. Untitled. Prose. 5. Anonymous. Untitled. Picture. 5. Anonymous. Untitled. Prose. 5. Chaparral. Show This to the Livy. Prose. 5. Lemon Punch. Show This to the Livy. Prose. 5. Burr, Leigh. Fair and Warmer. Prose. 5. Judge. Fair and Warmer. Prose. 5. Record. Fair and Warmer. Prose. 5. Anonymous. Cutting, Isn\u27t It?. Picture. 6. Vogel, W.A. Twentieth Century Romance. Prose. 7. Q. Meditation. Poem. 8. M.I.D. Morning, The Seventeenth. Poem. 8. Anonymous. The Engagement. Poem. 8. Rine, Russell. On Rolling Pins. Poem. 9. G.M.C. Evening Star. Poem. 9. G.M.C. An Orison. Poem. 9. Schmitz. Denison Ding Dongs. Poem/Picture. 10. Anonymous. Untitled. Prose. 11. Anonymous. Untitled. Prose. 11. Anonymous. Untitled. Prose. 11. Anonymous. Untitled. Prose. 11. Anonymous. Untitled. Prose. 11. Anonymous. Untitled. Poem. 11. Anonymous. Untitled. Picture. 11. Anonymous. Untitled. Poem. 11. Anonymous. Untitled. Picture. 11. Anonymous. Untitled. Prose. 11. Anonymous. Untitled. Prose. 11. Anonymous. Untitled. Poem. 11. Anonymous. Untitled. Prose. 11. Anonymous. Untitled. Prose. 11. Anonymous. Untitled. Prose. 11. Deluber. Untitled. Picture. 12. Anonymous. Untitled. Prose. 12. Anonymous. Untitled. Prose. 12. Anonymous. The Circus. Poem. 12. Anonymous. Untitled. Prose. 12. Anonymous. The Deuce You Say. Prose. 12. Anonymous. Untitled. Prose. 12. Anonymous. Untitled. Prose. 12. Anonymous. WHERE ARE YOU GOING MY PRETTY MAID? I\u27M GOING OUT FOR CHOW, SHE SAID. Picture. 12. Anonymous. E.E. Mongomery, M.D. Prose. 13. Anonymous. One Gone. Prose. 14. Anonymous. You\u27re Out. Prose. 15. W.G.M. Spring, B\u27gosh. Prose. 15. Bridge. Denison Folies. Picture. 16. W.M.P. New Fiction. Prose. 18. Schmitz. WHAT\u27S THE FARE TO KALAMAZOO? STANDARD RATES, $20.50. HOW MUCH FOR A SEAT? . Picture. 18. E.T. HE— WHAT\u27S THAT PRETTY THING YOU\u27RE WEARING UNDER YOUR \u27DOFUNNY?\u27 SHE— OH, THAT\u27S A SLIP. HE— I BEG YOUR PARDON. . Picture. 18. Anonymous. Untitled. Prose. 18. Anonymous. Untitled. Prose. 18. Anonymous. Untitled. Prose. 18. Anonymous. Untitled. Prose. 18. Anonymous. Untitled. Prose. 18. Anonymous. Untitled. Prose. 20. Anonymous. Untitled. Prose. 20. Anonymous. Untitled. Prose. 20. Anonymous. The Flapper\u27s Standard. Prose. 20. George. Y\u27OTTA SEE MY NEW GIRL. I CALL HER MY LITTLE SHYLOCK. JEWESS? NO, BOBBED HAIR. . Picture. 20. Anonymous. Untitled. Prose. 21. Anonymous. Read Aloud. Prose. 21. Anonymous. Untitled. Prose. 21. Anonymous. Untitled. Poem. 21. Anonymous. Untitled. Prose. 21. Anonymous. Untitled. Prose. 21. Anonymous. Untitled. Prose. 21. Anonymous. Untitled. Prose. 21. Anonymous. Untitled. Prose. 21. Whiz Bang. Untitled. Prose. 21. Awgwan. And Close It As You Go Out. Prose. 22. Wasp. Untitled. Prose. 22. Octopus. Untitled. Prose. 22. Anonymous. S. STORY THE ORIGINAL DAYLIGHT SAVER. Picture. 23. Wag Jag. Two Cokes, Garcon. Prose. 23. Boston Transcript. Untitled. Prose. 24. Siren. Untitled. Prose. 24. Widow. You Noah. Prose. 24. Anonymous. Deep Stuff. Prose. 27. Anonymous. Untitled. Prose. 27. Anonymous. Untitled. Prose. 27. Garber, Jock. Our Questionable Department. 29. Chaparral. Dayton?. Prose. 29. Banter. Untitled. Prose. 29. Burr. Untitled. Prose. 29. Anonymous. Untitled. Poem. 29. Octopus. Untitled. Poem. 29. B.N.E. Untitled. Poem. 30. Reel, Virginia. Untitled. Prose. 30. Octopus. Untitled. Prose. 31. Octopus. Untitled. Prose. 31. Ghost. Untitled. Prose. 31. Phoenix. Untitled. Prose. 31. Chaparral. Untitled. Prose. 31. Goblin. Untitled. Prose. 31. Banter. Untitled. Prose. 31. Jester. Untitled. Prose. 31. Scalper. Untitled. Prose. 32. Punch Bowl. A Pressing Matter. Prose. 32. Lyre. Untitled. Prose. 32. Punch Bowl. Y.W.C.A. Wanted. Prose. 32. Awgwan. Untitled. Prose. 32. Octopus. Politics. Prose. 32

    Tissue oxygenation with graded dissolved oxygen delivery during cardiopulmonary bypass

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    AbstractBackground: Intravascular perfluorochemical emulsions together with a high oxygen tension may increase the delivery of dissolved oxygen to useful levels. The hypothesis of this study is that increasing the dissolved oxygen content of blood with incremental doses of a perfluorochemical emulsion improves tissue oxygenation during cardiopulmonary bypass in a dose-related fashion. Methods and Results: Oxygen utilization was studied in a profoundly anemic canine model of hypothermic cardiopulmonary bypass. Forty-two dogs (mean ± standard error of the mean). Cardiopulmonary bypass was begun and resulted in a hematocrit of 9.4% + 0.6%. A standard primng solution was used in the control group (n = 12), and the test groups received 1.35 gm perfluorochemical · kg-1 (n = 10 dogs), or 5.4 gm perfluorochemical · kg-1 (n = 10 dogs), 2.7 gm perfluorochemical · kg-1(n = 10 dogs) through the venous return cannula. Each animal underwent a series of randomized pump flows (0.25,0.5, 1.0, 1.5, 2.0, and 3.0 L · min-1 · m-2 ) at 32° C. After the randomized flows were completed at 32° C, the temperature was raised to 38° C and cardiopulmonary bypass was discontinued. Mortality from cardiac failure on separation from cardiopulmonary bypass was 42% in the control group and 20% in perfluorochemical-treated groups. The mean perfluorochemical dose was higher in surviviors than in nonsurvivors (2.9 + 0.4 versus 1.3 + 0.5 gm perfluorochemical · kg-1; p < 0.05). No differences in oxygen consumption or transbody lactate gradient were found between groups during cardiopulmonary bypass. Analysis of mixed venous oxygen tension (a surrogate measure for tissue oxygenation) as a function of cardiopulmonary bypass flow normalized to body surface area showed that the control group had significantly lower mixed venous oxygen tension (p < 0.05) than the perfluorochemical emulsion-treated groups. Furthermore, the differences were related to the perfluorochemical emulsion dose. These differences in mixed venous oxygen tension continued after termination of cardiopulmonary bypass. The coronary sinus oxygen tension and cardiac arterial-venous oxygen content differences during and after cardiopulmonary bypass were similar among the control and perfluorochemical emulsion-treated animals. Dissolved oxygen consumption during and after cardiopulmonary bypass was calculated. Dissolved oxygen consumption increased in the perfluorochemical-treated animals in a perfluorochemical dose-related manner and was significantly higher in perfluoro-chemical-treated animals than in the control animals (p < 0.05). Conclusions: Graded increases in mixed venous oxygen tension during cardiopulmonary bypass were observed in response to graded increases in the dissolved oxygen delivery. These data suggest that enhancing oxygenation with perfluorochemical-dissolved oxygen is an effective temporary substitute for the use of hemoglobin-bound oxygen during cardiopulmonary bypass. Perfluorochemical-dissolved oxygen may be particularly beneficial in the setting of multiple hypoxic stresses. (J THORAC CARDIOVASC SURG 1995;110: 774-85)J THORAC CARDIOVASC SURG 1995;110:1-85

    Moyo Vol. IV N 1

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    Gilmore, Seth. A Note From Our Fearless Leader . 3. Aufrance, Jeremy. Oral Sects: A Look at Denison\u27s Music Scene . 4. Blake, Ben. Pay Attention! . 9. Russell, Mark. Above & Below: Unearthing the Denison Underground . 10. Gilmore, Seth. The Death of Cooties . 12. Christie, Carey. Summer Whoroscopes: Something for Every Sinner . 19. Mathews, Peter Edward. Sankofa: The Africa Inside Us All . 20. Perry, Andrea. Taking it Off: Denison\u27s Hidden history De-robed . 22. Clamurro, William H. Sexual Deviance: A Clamurrian Analysis . 24. Trabert, Heather. Get Out! (But Kindly Leave Your Wallets Behind) . 26

    Mars Aeronomy Observer: Report of the Science Working Team

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    The Mars Aeronomy Observer (MAO) is a candidate follow-on mission to Mars Observer (MO) in the Planetary Observer Program. The four Mariner and two Viking spacecraft sent to Mars between 1965 and 1976 have provided a wealth of information concerning Martian planetology. The Mars Observer, to be launched in 1990, will build on their results by further examining the elemental and mineralogical composition of the surface, the strength and multipolar composition of the planetary magnetic field, the gravitational field and topography, and the circulation of the lower atmosphere. The Mars Aeronomy Observer is intended to address the last major aspects of Martian environment which have yet to be investigated: the upper atmosphere, the ionsphere, and the solar wind interaction region

    Mitigation of Crack Damage in Metallic Materials

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    A system designed to mitigate or heal crack damage in metallic materials has been developed where the protected material or component is coated with a low-melting temperature film. After a crack is formed, the material is heated, melting the film which then infiltrates the crack opening through capillary action. Upon solidification, the healing material inhibits further crack damage in two ways. While the crack healing material is intact, it acts like an adhesive that bonds or bridges the crack faces together. After fatigue loading damages, the healing material in the crack mouth inhibits further crack growth by creating artificially-high crack closure levels. Mechanical test data show that this method sucessfully arrests or retards crack growth in laboratory specimens

    Ozone depletion events observed in the high latitude surface layer during the TOPSE aircraft program

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    During the Tropospheric Ozone Production about the Spring Equinox (TOPSE) aircraft program, ozone depletion events (ODEs) in the high latitude surface layer were investigated using lidar and in situ instruments. Flight legs of 100 km or longer distance were flown 32 times at 30 m altitude over a variety of regions north of 58° between early February and late May 2000. ODEs were found on each flight over the Arctic Ocean but their occurrence was rare at more southern latitudes. However, large area events with depletion to over 2 km altitude in one case were found as far south as Baffin Bay and Hudson Bay and as late as 22 May. There is good evidence that these more southern events did not form in situ but were the result of export of ozone-depleted air from the surface layer of the Arctic Ocean. Surprisingly, relatively intact transport of ODEs occurred over distances of 900–2000 km and in some cases over rough terrain. Accumulation of constituents in the frozen surface over the dark winter period cannot be a strong prerequisite of ozone depletion since latitudes south of the Arctic Ocean would also experience a long dark period. Some process unique to the Arctic Ocean surface or its coastal regions remains unidentified for the release of ozone-depleting halogens. There was no correspondence between coarse surface features such as solid ice/snow, open leads, or polynyas with the occurrence of or intensity of ozone depletion over the Arctic or subarctic regions. Depletion events also occurred in the absence of long-range transport of relatively fresh “pollution” within the high latitude surface layer, at least in spring 2000. Direct measurements of halogen radicals were not made. However, the flights do provide detailed information on the vertical structure of the surface layer and, during the constant 30 m altitude legs, measurements of a variety of constituents including hydroxyl and peroxy radicals. A summary of the behavior of these constituents is made. The measurements were consistent with a source of formaldehyde from the snow/ice surface. Median NOx in the surface layer was 15 pptv or less, suggesting that surface emissions were substantially converted to reservoir constituents by 30 m altitude and that ozone production rates were small (0.15–1.5 ppbv/d) at this altitude. Peroxyacetylnitrate (PAN) was by far the major constituent of NOy in the surface layer independent of the ozone mixing ratio

    Linking Activity, Nutrition, and Child Health (Launch): Protocol for a Longitudinal Cohort Study of Children as They Develop From Infancy to Preschool Age

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    Background Physical activity is known to provide important health benefits in children ages 3 years and above, but little is known about the effects of physical activity on health in very young children under age 3. LAUNCH (Linking Activity, Nutrition, and Child Health) is a study designed to expand the body of knowledge on development of physical activity behavior and associations between physical activity and other health characteristics as children transition from infancy to preschool age. Methods Physical activity and sedentary behavior will be measured objectively in young children over a period of 30 months. Each child will complete a measurement protocol at 6, 12, 18, 24, 30 and 36 months of age. The following factors will be measured at each time point: physical activity, sedentary behavior, anthropometric characteristics, and motor developmental status. Objectively-measured sleep behavior will be included as an optional component of the protocol. Parents will provide information on demographic factors, parenting behaviors, home and childcare characteristics, and the child’s dietary and sleep behaviors. Discussion LAUNCH will employ a longitudinal study design and objective measures of physical activity, sedentary behavior and sleep in examining developmental trends for those characteristics in children between the ages of 6 and 36 months. Associations among physical activity, sedentary behavior, sleep, and weight status will be examined. Findings will inform public health guidance and intervention strategies for very young children
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