212 research outputs found
Проект модернизации системы теплоснабжения объектов газового промысла от газопоршневой электростанции
Проект модернизации системы теплоснабжения объектов газового промысла от газопоршневой электростанции.The project of modernization of heat supply system of objects of gas field from gas power plants
Injectivity of sections of convex harmonic mappings and convolution theorems
In the article the authors consider the class of
sense-preserving harmonic functions defined in the unit disk
and normalized so that and , where
and are analytic in the unit disk. In the first part of the article we
present two classes and of
functions from and show that if
and , then the harmonic convolution is a univalent
and close-to-convex harmonic function in the unit disk provided certain
conditions for parameters and are satisfied. In the second
part we study the harmonic sections (partial sums) where , and denote the -th partial sums of
and , respectively. We prove, among others, that if
is a univalent harmonic convex mapping,
then is univalent and close-to-convex in the disk for
, and is also convex in the disk for
and . Moreover, we show that the section of is not convex in the disk but is shown to be convex
in a smaller disk.Comment: 16 pages, 3 figures; To appear in Czechoslovak Mathematical Journa
Translation, Cross-Cultural Adaptation, and Validation of the Pain Sensitivity Questionnaire in Dutch Healthy Volunteers
Contains fulltext :
221714.pdf (publisher's version ) (Open Access
Certain subclasses of multivalent functions defined by new multiplier transformations
In the present paper the new multiplier transformations
\mathrm{{\mathcal{J}% }}_{p}^{\delta }(\lambda ,\mu ,l) (\delta ,l\geq
0,\;\lambda \geq \mu \geq 0;\;p\in \mathrm{% }%\mathbb{N} )} of multivalent
functions is defined. Making use of the operator two new subclasses and \textbf{\ }of multivalent analytic
functions are introduced and investigated in the open unit disk. Some
interesting relations and characteristics such as inclusion relationships,
neighborhoods, partial sums, some applications of fractional calculus and
quasi-convolution properties of functions belonging to each of these subclasses
and
are
investigated. Relevant connections of the definitions and results presented in
this paper with those obtained in several earlier works on the subject are also
pointed out
A putative relay circuit providing low-threshold mechanoreceptive input to lamina I projection neurons via vertical cells in lamina II of the rat dorsal horn
Background:
Lamina I projection neurons respond to painful stimuli, and some are also activated by touch or hair movement. Neuropathic pain resulting from peripheral nerve damage is often associated with tactile allodynia (touch-evoked pain), and this may result from increased responsiveness of lamina I projection neurons to non-noxious mechanical stimuli. It is thought that polysynaptic pathways involving excitatory interneurons can transmit tactile inputs to lamina I projection neurons, but that these are normally suppressed by inhibitory interneurons. Vertical cells in lamina II provide a potential route through which tactile stimuli can activate lamina I projection neurons, since their dendrites extend into the region where tactile afferents terminate, while their axons can innervate the projection cells. The aim of this study was to determine whether vertical cell dendrites were contacted by the central terminals of low-threshold mechanoreceptive primary afferents.
Results:
We initially demonstrated contacts between dendritic spines of vertical cells that had been recorded in spinal cord slices and axonal boutons containing the vesicular glutamate transporter 1 (VGLUT1), which is expressed by myelinated low-threshold mechanoreceptive afferents. To confirm that the VGLUT1 boutons included primary afferents, we then examined vertical cells recorded in rats that had received injections of cholera toxin B subunit (CTb) into the sciatic nerve. We found that over half of the VGLUT1 boutons contacting the vertical cells were CTb-immunoreactive, indicating that they were of primary afferent origin.
Conclusions:
These results show that vertical cell dendritic spines are frequently contacted by the central terminals of myelinated low-threshold mechanoreceptive afferents. Since dendritic spines are associated with excitatory synapses, it is likely that most of these contacts were synaptic. Vertical cells in lamina II are therefore a potential route through which tactile afferents can activate lamina I projection neurons, and this pathway could play a role in tactile allodynia
Neuronal circuitry for pain processing in the dorsal horn
Neurons in the spinal dorsal horn process sensory information, which is then transmitted to several brain regions, including those responsible for pain perception. The dorsal horn provides numerous potential targets for the development of novel analgesics and is thought to undergo changes that contribute to the exaggerated pain felt after nerve injury and inflammation. Despite its obvious importance, we still know little about the neuronal circuits that process sensory information, mainly because of the heterogeneity of the various neuronal components that make up these circuits. Recent studies have begun to shed light on the neuronal organization and circuitry of this complex region
Gene expression changes and community turnover differentially shape the global ocean metatranscriptome
Ocean microbial communities strongly influence the biogeochemistry, food webs, and climate of our planet. Despite recent advances in understanding their taxonomic and genomic compositions, little is known about how their transcriptomes vary globally. Here, we present a dataset of 187 metatranscriptomes and 370 metagenomes from 126 globally distributed sampling stations and establish a resource of 47 million genes to study community-level transcriptomes across depth layers from pole-to-pole. We examine gene expression changes and community turnover as the underlying mechanisms shaping community transcriptomes along these axes of environmental variation and show how their individual contributions differ for multiple biogeochemically relevant processes. Furthermore, we find the relative contribution of gene expression changes to be significantly lower in polar than in non-polar waters and hypothesize that in polar regions, alterations in community activity in response to ocean warming will be driven more strongly by changes in organismal composition than by gene regulatory mechanisms
Presynaptically Localized Cyclic GMP-Dependent Protein Kinase 1 Is a Key Determinant of Spinal Synaptic Potentiation and Pain Hypersensitivity
Electrophysiological and behavioral experiments in mice reveal that a cGMP-dependent kinase amplifies neurotransmitter release from peripheral pain sensors, potentiates spinal synapses, and leads to exaggerated pain
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