Vehicle lead-acid battery state-of-charge meter

We describe a state-of-charge, or “residual-capacity” meter for lead-acid batteries that intelligently synthesizes coulometric and terminal-voltage methods in a new algorithm to provide reliable, continuous readout of remaining capacity. Novel electronic circuit design eliminates the need to install a shunt in the vehicle. The meter learns the characteristics of a battery to which it is attached, removing the need for setup, customisation, programming or calibration at time of installation or battery replacement. The meter can thus be installed by unqualified personnel. Initial measurements suggest the design to be robust and accurate

Laser Based Underwater Communication Systems

We report on recent progress in the field of visible light communications including direct modulation of blue laser devices at data rates beyond 10 Gbit/s, and the transmission of 2.5 Gbit/s OOK data through water. We also discuss the advantages of operating with single mode laser devices and matched filtering at the receiver in the context of applications with significant solar background. The system performance for two types of direct-detection receivers, a PIN detector and less conventional silicon Photomultiplier technology will be presented

Multi-service highly sensitive rectifier for enhanced RF energy scavenging

Due to the growing implications of energy costs and carbon footprints, the need to adopt inexpensive, green energy harvesting strategies are of paramount importance for the long-term conservation of the environment and the global economy. To address this, the feasibility of harvesting low power density ambient RF energy simultaneously from multiple sources is examined. A high efficiency multi-resonant rectifier is proposed, which operates at two frequency bands (478-496 and 852-869 MHz) and exhibits favorable impedance matching over a broad input power range (40 to 10 dBm). Simulation and experimental results of input reflection coefficient and rectified output power are in excellent agreement, demonstrating the usefulness of this innovative low-power rectification technique. Measurement results indicate an effective efficiency of 54.3%, and an output DC voltage of 772.8 mV is achieved for a multi-tone input power of '10 dBm. Furthermore, the measured output DC power from harvesting RF energy from multiple services concurrently exhibits a 3.14 and 7.24 fold increase over single frequency rectification at 490 and 860 MHz respectively. Therefore, the proposed multi-service highly sensitive rectifier is a promising technique for providing a sustainable energy source for low power applications in urban environments

Physiology students can use a quality improvement approach to support a safe and efficient medication pathway in geriatric rehabilitation

Peer reviewedPublisher PD

Measurement of turbulent velocity, intensity and scale in rod bundle flow channels

An experimental study was performed to investigate the effect of flow channel geometry on fully developed turbulent flow in "clean" rod bundle flow channels. This information was sought to obtain a better understanding of crossflow mixing between rod bundle subchannels. The experiments were performed in water with a Reynolds number range from 50,000 to 200,000. The experimental flow models considered pitch-to-diameter ratios of 125 and 1.125. Axial components of velocity, turbulence intensity and Eulerian autocorrelation function were the primary measurements. The autocorrelation function provided an indication of the dominant frequency of turbulence and an estimate of the longitudinal macroscale by using Taylor's hypothesis. A limited amount of lateral component turbulence intensity data was also obtained. The experimental results show that rod gap spacing (pitch-to-diameter ratio) is the most significant geometric parameter affecting the flow structure. Decreasing the rod gap spacing increased the turbulence intensity, longitudinal macroscale, and the dominant frequency of turbulence. These turbulence parameters were found to be rather insensitive to Reynolds number. The turbulence parameters within a rod gap were found to be insensitive to the shape of adjacent subchannels and only slightly affected by the amount of lateral freedom allowed by the various size flow models. The results indicate that macroscopic flow processes exist adjacent to the rod gap. This includes secondary flows and increased scale and frequency of flow pulsations when the rod gap spacing is reduced. When interpreted in terms of crossflow mixing, the results are consistent with present crossflow mixing correlations

Aphid feeding induces phytohormonal cross-talk without affecting silicon defense against subsequent chewing herbivores

Prior feeding by insect herbivores frequently affects plant quality for herbivores that subsequently feed on the plant. Facilitation occurs when one herbivore improves plant quality for other herbivores, including when the former compromises plant defenses. Silicon (Si) is an important defense in grasses that increases following activation of the jasmonic acid (JA) pathway. Given that aphids often stimulate the salicylic acid (SA) pathway, we hypothesized that this could reduce Si defense because of the well documented antagonistic cross-talk between SA and JA. We tested this in the model grass Brachypodium distachyon with and without Si (+Si and −Si, respectively); half of the plants were exposed to aphids (Rhopalosiphum padi) and half remained aphid-free. Aphid-free and aphid-exposed plants were then fed to chewing herbivores (Helicoverpa armigera). Aphids triggered higher SA concentrations which suppressed JA concentrations but this did not affect foliar Si. Chewing herbivores triggered higher JA concentrations and induced Si uptake, regardless of previous feeding by aphids. Chewer growth rates were not impacted by prior aphid herbivory but were reduced by 75% when feeding on +Si plants. We concluded that aphids caused phytohormonal cross-talk but this was overridden by chewing herbivory that also induced Si uptake

Field application of silicon alleviates drought stress and improves water use efficiency in wheat

Detrimental impacts of drought on crop yield have tripled in the last 50 years with climate models predicting that the frequency of such droughts will intensify in the future. Silicon (Si) accumulation, especially in Poaceae crops such as wheat (Triticum aestivum L.), may alleviate the adverse impacts of drought. We have very limited information, however, about whether Si supplementation could alleviate the impacts of drought under field conditions and no studies have specifically manipulated rainfall. Using field–based rain exclusion shelters, we determined whether Si supplementation (equivalent to 39, 78 and 117 kg ha-1) affected T. aestivum growth, elemental chemistry [Si, carbon (C) and nitrogen (N)], physiology (rates of photosynthesis, transpiration, stomatal conductance, and water use efficiency) and yield (grain production) under ambient and drought (50% of ambient) rainfall scenarios. Averaged across Si treatments, drought reduced shoot mass by 21% and grain production by 18%. Si supplementation increased shoot mass by up to 43% and 73% in ambient and drought water treatments, respectively, and restored grain production in droughted plants to levels comparable with plants supplied with ambient rainfall. Si supplementation increased leaf-level water use efficiency by 32–74%, depending on Si supplementation rates. Water supply and Si supplementation did not alter concentrations of C and N, but Si supplementation increased shoot C content by 39% and 83% under ambient and drought conditions, respectively. This equates to an increase from 6.4 to 8.9 tonnes C ha-1 and from 4.03 to 7.35 tonnes C ha-1 under ambient and drought conditions, respectively. We conclude that Si supplementation ameliorated the negative impacts of drought on T. aestivum growth and grain yield, potentially through its beneficial impacts on water use efficiency. Moreover, the beneficial impacts of Si on plant growth and C storage may render Si supplementation a useful tool for both drought mitigation and C sequestration

Effectiveness and Safety of Tranexamic Acid Use in Acute Traumatic Injury in the Prehospital and In-hospital Settings: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Background and Objectives: This systematic review and meta-analysis of randomized controlled trials (RCTs) aims to assess efficacy and safety of tranexamic acid (TXA) use in acute traumatic injuries. Methods: PubMed and Cochrane libraries were searched for relevant RCTs published between January 2011 and January 3, 2021. Cohen’s Q Test for heterogeneous effects was used to determine the appropriateness of fixed versus random effects models. Results: Twenty-two studies met inclusion criteria. Meta-analysis of relative risk of mortality between treatment and placebo groups in the in-hospital, and perioperative settings was not significant. However, the risk of mortality is significantly lower in the treatment versus placebo group when TXA was given as loading dose only. Ten of the 11 studies evaluating perioperative use of TXA included in systematic review found significantly lower blood loss in the treatment compared with placebo groups, but results of meta-analysis showed no significant difference. Results of meta-analysis indicate that the risk of venous thromboembolism (VTE) in the in-hospital treatment group is greater than that of the placebo. In subset analysis of studies using only a single loading dose, there were no significant differences in VTE. Conclusions: Systematic review supports TXA benefits are most evident when given shortly after injury and meta-analysis supports TXA reduces mortality as a single loading dose. Systematic review supports perioperative use of TXA when large volume blood loss is anticipated. Meta-results showed no significant difference in risk of thromboembolism in single-dose TXA treatment compared with placebo. These findings suggest that TXA is safe and effective for control of traumatic bleeding. Mini-abstract: This systematic review indicates that tranexamic acid (TXA) is most beneficial when given shortly postinjury and TXA given preoperatively reduces intraoperative blood loss. Meta-analysis reveals single-dose TXA was associated with improved mortality with no significant difference in VTE risk or complications. Cohesive guidelines are needed

Creating the good life? A wellbeing perspective on cultural value in rural development

This is the final version. Available on open access from Elsevier via the DOI in this recordIn the last two decades academic and policy interest in the economic growth potential of the cultural sector has risen sharply in UK, as well as in other OECD countries. Alongside this there has been a shift in cultural policies away from a focus on the public value of culture to the economic value of creativity. Where public funds are allocated to arts and culture this is heavily and increasingly skewed towards London. Although there is wide recognition of the intrinsic value of the arts and the inequalities of provision, culture is increasingly invoked as a narrowly instrumental concept for other policy aims. The new discourses of creative economies have been slow to reach rural studies and where discussions of the 'creative countryside' have taken place, notions of rural cultural value remain largely within an instrumentalist discourse. This paper is an attempt to shift the discussion to new ground by exploring cultural value through the lens of a social justice approach to wellbeing, based on the capabilities approach, using material from an AHRC funded year-long knowledge exchange project with rural arts organisations in Northumberland. The paper argues against the narrow instrumentalism of culture as a delivery mechanism for other policy agendas and offers a different conceptual framework based on social justice for considering the value of culture in conceptions of a 'good life'. It finds that using such an approach allows a different conceptual space and a clearer normative basis for understanding and arguing for the intrinsic value of culture in rural development.Arts and Humanities Research Council (AHRC

Overview of Serological Techniques for Influenza Vaccine Evaluation: Past, Present and Future

Serological techniques commonly used to quantify influenza-specific antibodies include the Haemagglutination Inhibition (HI), Single Radial Haemolysis (SRH) and Virus Neutralization (VN) assays. HI and SRH are established and reproducible techniques, whereas VN is more demanding. Every new influenza vaccine needs to fulfil the strict criteria issued by the European Medicines Agency (EMA) in order to be licensed. These criteria currently apply exclusively to SRH and HI assays and refer to two different target groups—healthy adults and the elderly, but other vaccine recipient age groups have not been considered (i.e., children). The purpose of this timely review is to highlight the current scenario on correlates of protection concerning influenza vaccines and underline the need to revise the criteria and assays currently in use. In addition to SRH and HI assays, the technical advantages provided by other techniques such as the VN assay, pseudotype-based neutralization assay, neuraminidase and cell-mediated immunity assays need to be considered and regulated via EMA criteria, considering the many significant advantages that they could offer for the development of effective vaccines