Acrocyanosis, digital ischemia and acronecrosis as first manifestations of endometrial adenocarcinoma: case presentation and literature review

The association between digital ischemia and cancer is rarely reported in literature and the exact mechanism of this occurrence has not been completely understood. We report here a case of a 73 yearold woman who presented digital ischemia as first manifestation of endometrial adenocarcinoma. Reporting this rare clinical case and with a brief literature review, we recommend to consider an intensive search for primary and metastatic cancer in all patients who experience a digital ischemia, with the aim to early detect and treat the disease

Robot kinematic structure classification from time series of visual data

In this paper we present a novel algorithm to solve the robot kinematic structure identification problem. Given a time series of data, typically obtained processing a set of visual observations, the proposed approach identifies the ordered sequence of links associated to the kinematic chain, the joint type interconnecting each couple of consecutive links, and the input signal influencing the relative motion. Compared to the state of the art, the proposed algorithm has reduced computational costs, and is able to identify also the joints' type sequence

Primary Aldosteronism: A Glimpse into the Most Common Endocrine Cause of Arterial Hypertension

Compelling evidences showed that primary aldosteronism (PA) is a quite common disease. In spite of this, hypertensive patients are seldom screened for PA and, therefore, many patients are mislabelled as (low-renin) essential hypertension thereby remaining exposed to the nefarious consequences of long-term hyperaldosteronism. In this chapter we reviewed the clinical aspects of PA and the evidences supporting the need of implementing strategies aimed at diagnosing early PA patients. After reporting the prevalence rates of PA in different cohorts of hypertensive patients, we examined the reasons why PA is rarely searched for. The cardiovascular and renal damage associated with PA were also discussed, with particular emphasis to endothelial dysfunction, vascular remodeling, left ventricular changes, fibrosis, diastolic dysfunction, atrial fibrillation and chronic kidney disease. Studies supporting the concept that PA-associated organ damage can be prevented and even regressed with a timely diagnosis were also reviewed. A flowchart illustrating the proposal of a simplified diagnostic algorithm for screening and subtyping of PA, which allows circumventing the complexity of a diagnostic workup centred on confirmatory tests, is also proposed. Finally, the principles of treatment for PA are discussed

Production, efficiency and corruption in Italian Serie A : a DEA analysis

This paper uses data from Italian Serie A football to analyse the technical efficiency of Italian football clubs , utilising a panel dataset comprising season aggregated match statistics over ten seasons from 2000/01 to 2009/10 inclusive . While there has been considerable research on production and efficiency in most of the major European football leagues , corresponding evidence relating to Serie A is limited. T his paper addresses this imbalance , e stimating a production function for the league and the relative efficiency of 36 teams , taking into consideration the impact of the Calciopoli corruption scan dal in 2006 . To achieve this , Da ta Envelopment Analysis (DEA) models ha ve been used to calculate the frontiers of efficient production. The results highlight how playing style has changed in response to the corruption scandal , emphasizing the importance of attacking play in Serie A

Evaluating the impact of eDoS attacks to cloud facilities

The complexity of modern cloud facilities requires attentive management policies that should encompass all aspects of the system. Security is a critical issue, as intrusions, misuse or denial of service attacks may damage both the users and the cloud provider including its reputation on the market. Disruptive attacks happen fast, cause evident and short term damages and are usually the result of operations that are hard to disguise. On the other hand, Energy oriented Denial of Service (eDoS) attacks aim at producing continuous minor damages, eventually with long term consequences. These long lasting attacks are difficult to detect. In this paper we model and analyse the behaviour of a system under eDoS attack. We study the impact in terms of cloud energy consumption of an attack strategy previously proposed in the literature and compare it with other strategies that we propose. Our findings show that the strategy previously proposed in the literature, based on keeping the cloud close to saturation, is not optimal (from the point of view of the attacker) in presence of non-constant workload and that there is a trade-off between the aggressiveness of the attacker and the duration of the attack in order to maximise the damage

Response to Renal Function in Primary Aldosteronism: Is Glomerular Hyperfiltration a Hallmark of Primary Aldosteronism? Further Results from the Primary Aldosteronism Prevalence in Hypertension (PAPY) Study

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Idiopathic Eosinophilic Pneumonia with Associated Pulmonary Vasculitis in Horse: A Case Series

Various eosinophilic lesions and their association with diseases have been described in horses. Multisystemic Eosinophilic Epitheliotropic Disease (MEED) characterized by eosinophilic granulomas in various organs represent the most diffuse manifestation. In the present study, we describe the gross and microscopic lesions of idiopathic eosinophilic pneumonia with associated pulmonary vasculitis in 11 horses without systemic involvement. Lungs were enlarged, pale pink, poorly collapsed with white-reddish nodules, randomly distributed throughout the parenchyma. Histologically the lesions ranged from mild eosinophilic bronchointerstitial pneumonia to severe eosinophilic lobular bronchopneumonia associated with eosinophilic necrotizing vasculitis affecting small to medium-size vessels. There was no histologic evidence of parasites within the lesion of any of these horses. Eosinophilic pneumonia with vasculitis and without intralesional parasites have not been previously reported in horses. The current histologic findings are similar to pathologic lung findings observed in Churg-Strauss syndrome of man