'Where' questions and their responses in Duna (Papua New Guinea)

Despite their central role in question formation, content interrogatives in spontaneous conversation remain relatively under-explored cross-linguistically. This paper outlines the structure of ‘where’ expressions in Duna, a language spoken in Papua New Guinea, and examines where-questions in a small Duna data set in terms of their frequency, function, and the responses they elicit. Questions that ask ‘where?’ have been identified as a useful tool in studying the language of space and place, and, in the Duna case and elsewhere, show high frequency and functional flexibility. Although where-questions formulate place as an information gap, they are not always answered through direct reference to canonical places. While some question types may be especially “socially costly” (Levinson 2012), asking ‘where’ perhaps provides a relatively innocuous way of bringing a particular event or situation into focus

Learning in complex tasks: A comparison of cognitvie load and dual space theories.

Cognitive Load Theory (CLT) and Dual Space Theory (DST) offer differing accounts of learning in complex settings. CLT argues that reducing processing demands on working memory (i.e. reducing cognitive load) will facilitate learning. Conversely, DST suggests that learning is improved by encouraging learners to focus on task rules (rule space search) rather than task instances (instance space search). Despite these differences, CLT researchers have proposed that the theories are complementary, suggesting that rule space search is contingent on low cognitive load. Three studies were conducted to examine this proposal with particular focus on the goal free effect. Study 1 trained participants on a complex task under conditions of high or low rule space search with cognitive load held constant. Results indicated that the high rule space search group acquired greater knowledge despite equivalent cognitive load between the groups. However, results may have been confounded by motivational differences. Study 2 manipulated rule space search and cognitive load in a 2 (goal type) x 2 (information level) between-subjects design. Manipulations were intended to create conditions where cognitive load and rule space search were both high or low, contrary to their proposed dependence. Results however were mixed. Whilst cognitive load and rule space search were unrelated in between-group comparisons, they were negatively related overall, consistent with CLT’s proposal. Study 3 refined the previous 2 x 2 design to clarify these findings. Results indicated that groups encouraged to search rule space did so independently of cognitive load, though results were not entirely consistent with either theory. Taken together, results tentatively suggest that cognitive load does not influence rule space search in all situations. The theories may therefore be independent explanations of learning in complex settings

An integrated agroforestal suitability model using a GIS-based multicriteria analysis method: A case study of Portugal

It is generally agreed that the choice of the most suitable uses based in soil and climatic factors, complemented with socio-economic criteria, promotes sustainable use of rural land. There are, however, different methodologies for defining the soil suitability to agroforestal systems or natural and seminatural ecosystems, including agricultural uses, forest plantations, agro-forestry areas and priority areas for nature conservation. Many of these methods rely on decision support systems based on multicriteria spatial analysis. In this study we intended to determine the different levels of suitability for agro-forestry use in a subregion located in the center of Portugal, near the border with Spain. To the effect we used a set of soil and topographic variables. The legal constraints and land cover were also included. The suitability evaluation was performed using the Analytic Hierarchy Process (AHP). A spatial analysis was also performed in order to confront the land use matrix with the soil potentiality. This analysis allows to identify areas where the use and management it is in accordance with their suitability, as well as areas where the use must be subject to a conversion or at least to a change of management mode.info:eu-repo/semantics/publishedVersio

Multiple conserved regulatory domains promote Fezf2 expression in the developing cerebral cortex.

BackgroundThe genetic programs required for development of the cerebral cortex are under intense investigation. However, non-coding DNA elements that control the expression of developmentally important genes remain poorly defined. Here we investigate the regulation of Fezf2, a transcription factor that is necessary for the generation of deep-layer cortical projection neurons.ResultsUsing a combination of chromatin immunoprecipitation followed by high throughput sequencing (ChIP-seq) we mapped the binding of four deep-layer-enriched transcription factors previously shown to be important for cortical development. Building upon this we characterized the activity of three regulatory regions around the Fezf2 locus at multiple stages throughout corticogenesis. We identified a promoter that was sufficient for expression in the cerebral cortex, and enhancers that drove reporter gene expression in distinct forebrain domains, including progenitor cells and cortical projection neurons.ConclusionsThese results provide insight into the regulatory logic controlling Fezf2 expression and further the understanding of how multiple non-coding regulatory domains can collaborate to control gene expression in vivo

Eye drop Self-medication: Comparative Questionnaire-based study of two Latin American cities.

A broad spectrum of ocular symptoms are treated by self-medication with commercial eye-drops.  This behavior threatens individuals' visual health. In Latin America, evidence is poor. Objective:  To  detect,  characterize  and  compare  patterns  of  ophthalmic  self-medication  between  Córdoba (Argentina) and Barranquilla (Colombia).Design:  Analytic, cross-sectional and comparative population-based study. Setting: Two private tertiary care ophthalmology centers from Córdoba, Argentina, and Barranquilla, Colombia.Participants:  Patients 18 years of age or older who consulted for the first time in this two institutions duringAugust-November 2009, were included. A number of 570 patients were enrrolled.Methods:  Data collected through a semi-structured questionnaire. Main outcome measure: To determine thefrequency of self-medication with eyedrops on a specific population of two cities in Latin America.Results:  Comparable  rates  of  ocular  self-medication  were  found  (25.6%  and  25.7%  for  Cordoba  and Barranquilla, respectively). The percentage of men and women who self-medicated was not significantly different between both samples. The major source of eye drops recommendation in the Argentineans patients was the pharmacist (31%); while the social source was predominant in Colombian individuals (53%). In Cordoba, the most frequently used product was a non-steroidal anti-inflammatory drop in combination with a vasoconstrictive agent (32%); while in Barranquilla, antibiotic eye drops were preferred (33%). Self-medication was higher between the ages of 31 and 50 years old in Argentinean citizens (28%) and between 18 to 31 years old in the Colombiancommunity (39%). This habit was found mostly in patients who completed university studies in Cordoba (33%); in Barranquilla, individuals with lower educational level practice more this behavior (36%).Conclusion:  In both populations, patients commonly treat ocular conditions by self-medicating. Currently, anincreasing number of eye drops are obtainable without prescription and a high percentage of self-medicated patients in both samples ignore the possible side effects of the used medication.Fil: Marquez, Gabriel. Fundación VER; ArgentinaFil: Hildegard Piñeros-Heilbron. Fundación Oftalmológica del Caribe; ColombiaFil: Sanchez, Victoria M.. Fundación VER; ArgentinaFil: Torres, Victor Eduardo Roque. Fundación VER; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigaciones y Estudios sobre Cultura y Sociedad. Universidad Nacional de Córdoba. Centro de Investigaciones y Estudios sobre Cultura y Sociedad; ArgentinaFil: Gramajo, Ana L.. Fundación VER; ArgentinaFil: Juarez, Claudio P.. Fundación VER; Argentina. Fundación Oftalmológica del Caribe; ColombiaFil: Peña, Fernando. Fundación Oftalmológica del Caribe; ColombiaFil: Luna, José D.. Fundación VER; Argentin