364 research outputs found

    California Miscellany II

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    California Miscellany III

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    The Principle of Normalization In Human Services

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    The underlying principles inherent in Normalization have lead to such recent developments as the United Nations Declaration of the Rights of Mentally Retarded Persons brought into being by the International League of Societies for the Mentally Handicapped. This book is the first one to document normalization from its origins in Scandinavian services to the mentally retarded to its implications to the field of human services. The National Institute on Mental Retardation has published this text to support the current growing interest in normalization concepts and fuller integration of the retarded into the community. This concept is currently having a major impact on the pattern of programming in a number of countries. The views expressed in this book do not neces­sarily reflect the Institute\u27s specific strategies, or those of its sponsor, the Canadian Association for the Mentally Retarded. The publication of The principle of normalization in human services, and earlier of Mental retardation • the law • guardianship and Standards for educators of exceptional children in Canada are examples of the Institute\u27s recently established publishing policy to bring to the attention of a wider public new concepts, innovative programs and reports of studies by the Institute itself and by others in the field of the mentally handicapped and in human services generally.https://digitalcommons.unmc.edu/wolf_books/1000/thumbnail.jp

    On the strict majorant property in arbitrary dimensions

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    In this work we study dd-dimensional majorant properties. We prove that a set of frequencies in Zd{\mathbb Z}^d satisfies the strict majorant property on Lp([0,1]d)L^p([0,1]^d) for all p>0p> 0 if and only if the set is affinely independent. We further construct three types of violations of the strict majorant property. Any set of at least d+2d+2 frequencies in Zd{\mathbb Z}^d violates the strict majorant property on Lp([0,1]d)L^p([0,1]^d) for an open interval of p∉2Np \not\in 2 {\mathbb N} of length 2. Any infinite set of frequencies in Zd{\mathbb Z}^d violates the strict majorant property on Lp([0,1]d)L^p([0,1]^d) for an infinite sequence of open intervals of p∉2Np \not\in 2 {\mathbb N} of length 22. Finally, given any p>0p>0 with p∉2Np \not\in 2{\mathbb N}, we exhibit a set of d+2d+2 frequencies on the moment curve in Rd{\mathbb R}^d that violate the strict majorant property on Lp([0,1]d).L^p([0,1]^d).Comment: 22 page

    Steklov problem on differential forms

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    In this paper we study spectral properties of Dirichlet-to-Neumann map on differential forms obtained by a slight modification of the definition due to Belishev and Sharafutdinov. The resulting operator Λ\Lambda is shown to be self-adjoint on the subspace of coclosed forms and to have purely discrete spectrum there.We investigate properies of eigenvalues of Λ\Lambda and prove a Hersch-Payne-Schiffer type inequality relating products of those eigenvalues to eigenvalues of Hodge Laplacian on the boundary. Moreover, non-trivial eigenvalues of Λ\Lambda are always at least as large as eigenvalues of Dirichlet-to-Neumann map defined by Raulot and Savo. Finally, we remark that a particular case of pp-forms on the boundary of 2p+22p+2-dimensional manifold shares a lot of important properties with the classical Steklov eigenvalue problem on surfaces.Comment: 18 page

    SU(3) Breaking Effects in Hyperon Semi-Leptonic Decays and the extraction of F and D

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    The analysis of hyperon semi-leptonic decay data is re-examined in the light of a recent suggestion that SU(3) symmetry breaking effects may be taken into account by applying a correction to the F/DF/D ratio obtained via naive linear extrapolation in the hyperon masses. Comparison is made with the physically better motivated approach of applying so-called centre-of-mass corrections. This study (including all available data) reveals certain short-comings of the former of the above treatments, highlights some interesting aspects of this type of analysis and attempts to pinpoint the decay data that might usefully be improved. A tantalising result of the SU(3) breaking analysis performed here is that the magnitude of recoil correction required by the data corresponds closely to that required for the standard explanation of the reduction of \gA from its SU(6) value of 5/3. We also comment on other recent suggestions for taking into account the effects of SU(3) breaking. Finally a few remarks are made on the relevance for predicting the flavour non-singlet contribution to the proton g1g_1 and the Ellis-Jaffe sum rule.Comment: 12 pages, latex, no figures. Removed extended ascii set characters in the source file that were being corrupted by some mailer

    A composite measure of cognitive and functional progression in Alzheimer's disease: Design of the Capturing Changes in Cognition study

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    markdownabstract__Introduction__ Cognitive testing in Alzheimer's disease (AD) is essential for establishing diagnosis, monitoring progression, and evaluating treatments. Assessments should ideally be brief, reliable, valid, and reflect clinically meaningful changes. There is a lack of instruments that meet all these criteria. In the Capturing Changes in Cognition (Catch-Cog) study, we seek to correct these deficiencies through the development and validation of a composite measure combining cognition and function: the cognitive-functional composite (CFC). We expect that the CFC is able to detect clinically relevant changes over time in early dementia stages of AD. __Methods/Design__ We will include patients (n = 350) with mild cognitive impairment or mild dementia due to AD from memory clinics in the Netherlands and the United Kingdom. We will include cognitively healthy volunteers (n = 30) as a control group. The CFC is based on the “cognitive composite” and the Amsterdam instrumental activities of daily living questionnaire. We will investigate test–retest reliability with baseline and 2- to 3-week follow-up assessments (n = 50 patients and n = 30 healthy controls). We will involve experts and participants to evaluate the initial feasibility and refine the CFC if needed. Subsequently, we will perform a longitudinal construct validation study in a prospective cohort (n = 300) with baseline, 3-, 6-, and 12-month follow-up assessments. The main outcome is cognitive and functional progression measured by the CFC. Reference measures for progression include traditional cognitive and functional tests, disease burden measures, and brain imaging methods. Using linear mixed modeling, we will investigate longitudinal changes on the CFC and relate these to the reference measures. Using linear regression analyses, we will evaluate the influence of possible confounders such as age, gender, and education on the CFC. __Discussion__ By performing an independent longitudinal construct validation, the Catch-Cog study of the novel CFC will contribute to the improvement of disease monitoring and treatment evaluation in early dementia stages of AD

    Detecting functional decline from normal aging to dementia: Development and validation of a short version of the Amsterdam IADL Questionnaire

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    Introduction Detecting functional decline from normal aging to dementia is relevant for diagnostic and prognostic purposes. Therefore, the Amsterdam IADL Questionnaire (A-IADL-Q) was developed: a 70-item proxy-based tool with good psychometric properties. We aimed to design a short version while preserving its psychometric quality. Methods Study partners of subjects (n = 1355), ranging from cognitively normal to dementia subjects, completed the original A-IADL-Q. We selected the short version items using a stepwise procedure combining missing data, Item Response Theory, and input from respondents and experts. We investigated internal consistency of the short version and concordance with the original version. To assess its construct validity, we additionally investigated concordance between the short version and the Mini–Mental State Examination (MMSE) and Disability Assessment for Dementia (DAD). Finally, we investigated differences in instrumental activities of daily living (IADL) scores between diagnostic groups across the dementia spectrum. Results We selected 30 items covering the entire spectrum of IADL functioning. Internal consistency (0.98) and concordance with the original version (0.97) were very high. Concordance with the MMSE (0.72) and DAD (0.87) scores was high. IADL impairment scores increased across the spectrum from normal cognition to dementia. Discussion The A-IADL-Q short version (A-IADL-Q-SV) consists of 30 items and has maintained the psychometric quality of the original A-IADL-Q. As such, the A-IADL-Q-SV is a concise measure of functional decline
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