EEG spike source localization before and after surgery for temporal lobe epilepsy: a BOLD EEG-fMRI and independent component analysis study

Simultaneous measurements of EEG-functional magnetic resonance imaging (fMRI) combine the high temporal resolution of EEG with the distinctive spatial resolution of fMRI. The purpose of this EEG-fMRI study was to search for hemodynamic responses (blood oxygen level-dependent - BOLD responses) associated with interictal activity in a case of right mesial temporal lobe epilepsy before and after a successful selective amygdalohippocampectomy. Therefore, the study found the epileptogenic source by this noninvasive imaging technique and compared the results after removing the atrophied hippocampus. Additionally, the present study investigated the effectiveness of two different ways of localizing epileptiform spike sources, i.e., BOLD contrast and independent component analysis dipole model, by comparing their respective outcomes to the resected epileptogenic region. Our findings suggested a right hippocampus induction of the large interictal activity in the left hemisphere. Although almost a quarter of the dipoles were found near the right hippocampus region, dipole modeling resulted in a widespread distribution, making EEG analysis too weak to precisely determine by itself the source localization even by a sophisticated method of analysis such as independent component analysis. On the other hand, the combined EEG-fMRI technique made it possible to highlight the epileptogenic foci quite efficiently.58258

Individualized prediction of illness course at the first psychotic episode: a support vector machine MRI study

To date, magnetic resonance imaging (MRI) has made little impact on the diagnosis and monitoring of psychoses in individual patients. In this study, we used a support vector machine (SVM) whole-brain classification approach to predict future illness course at the individual level from MRI data obtained at the first psychotic episode

EEG spike source localization before and after surgery for temporal lobe epilepsy: a BOLD EEG-fMRI and independent component analysis study

Simultaneous measurements of EEG-functional magnetic resonance imaging (fMRI) combine the high temporal resolution of EEG with the distinctive spatial resolution of fMRI. The purpose of this EEG-fMRI study was to search for hemodynamic responses (blood oxygen level-dependent - BOLD responses) associated with interictal activity in a case of right mesial temporal lobe epilepsy before and after a successful selective amygdalohippocampectomy. Therefore, the study found the epileptogenic source by this noninvasive imaging technique and compared the results after removing the atrophied hippocampus. Additionally, the present study investigated the effectiveness of two different ways of localizing epileptiform spike sources, i.e., BOLD contrast and independent component analysis dipole model, by comparing their respective outcomes to the resected epileptogenic region. Our findings suggested a right hippocampus induction of the large interictal activity in the left hemisphere. Although almost a quarter of the dipoles were found near the right hippocampus region, dipole modeling resulted in a widespread distribution, making EEG analysis too weak to precisely determine by itself the source localization even by a sophisticated method of analysis such as independent component analysis. On the other hand, the combined EEG-fMRI technique made it possible to highlight the epileptogenic foci quite efficiently

Eeg Spike Source Localization Before And After Surgery For Temporal Lobe Epilepsy: A Bold Eeg-fmri And Independentcomponent Analysis Study

Simultaneous measurements of EEG-functional magnetic resonance imaging (fMRI) combine the high temporal resolution of EEG with the distinctive spatial resolution of fMRI. The purpose of this EEG-fMRI study was to search for hemodynamic responses (blood oxygen level-dependent - BOLD responses) associated with interictal activity in a case of right mesial temporal lobe epilepsy before and after a successful selective amygdalohippocampectomy. Therefore, the study found the epileptogenic source by this noninvasive imaging technique and compared the results after removing the atrophied hippocampus. Additionally, the present study investigated the effectiveness of two different ways of localizing epileptiform spike sources, i.e., BOLD contrast and independent component analysis dipole model, by comparing their respective outcomes to the resected epileptogenic region. Our findings suggested a right hippocampus induction of the large interictal activity in the left hemisphere. Although almost a quarter of the dipoles were found near the right hippocampus region, dipole modeling resulted in a widespread distribution, making EEG analysis too weak to precisely determine by itself the source localization even by a sophisticated method of analysis such as independent component analysis. On the other hand, the combined EEG-fMRI technique made it possible to highlight the epileptogenic foci quite efficiently.426582587Engel Jr., J., Introduction to temporal lobe epilepsy (1996) Epilepsy Res, 26, pp. 141-150Ives, J.R., Warach, S., Schmitt, F., Edelman, R.R., Schomer, D.L., Monitoring the patient's EEG during echo planar MRI (1993) Electroencephalogr Clin Neurophysiol, 87, pp. 417-420Allen, P.J., Josephs, O., Turner, R., A method for removing imaging artifact from continuous EEG recorded during functional MRI (2000) Neuroimage, 12, pp. 230-239Ritter, P., Villringer, A., Simultaneous EEG-fMRI (2006) Neurosci Biobehav Rev, 30, pp. 823-838Zijlmans, M., Huiskamp, G., Hersevoort, M., Seppenwoolde, J.H., van Huffelen, A.C., Leijten, F.S., EEG-fMRI in the preoperative work-up for epilepsy surgery (2007) Brain, 130, pp. 2343-2353Lemieux, L., Krakow, K., Fish, D.R., Comparison of spike-triggered functional MRI BOLD activation and EEG dipole model localization (2001) Neuroimage, 14, pp. 1097-1104Bagshaw, A.P., Kobayashi, E., Dubeau, F., Pike, G.B., Gotman, J., Correspondence between EEG-fMRI and EEG dipole localisation of interictal discharges in focal epilepsy (2006) Neuroimage, 30, pp. 417-425Belliveau, J.W., Rosen, B.R., Kantor, H.L., Rzedzian, R.R., Kennedy, D.N., McKinstry, R.C., Functional cerebral imaging by susceptibility-contrast NMR (1990) Magn Reson Med, 14, pp. 538-546Ogawa, S., Lee, T.M., Kay, A.R., Tank, D.W., Brain magnetic resonance imaging with contrast dependent on blood oxygenation (1990) Proc Natl Acad Sci U S A, 87, pp. 9868-9872Delorme, A., Makeig, S., EEGLAB: An open source toolbox for analysis of single-trial EEG dynamics including independent component analysis (2004) J Neurosci Methods, 134, pp. 9-21Plummer, C., Harvey, A.S., Cook, M., EEG source localization in focal epilepsy: Where are we now? (2008) Epilepsia, 49, pp. 201-218Leal, A.J., Dias, A.I., Vieira, J.P., Analysis of the EEG dynamics of epileptic activity in gelastic seizures using decomposition in independent components (2006) Clin Neurophysiol, 117, pp. 1595-1601Kobayashi, E., Bagshaw, A.P., Benar, C.G., Aghakhani, Y., Andermann, F., Dubeau, F., Temporal and extratemporal BOLD responses to temporal lobe interictal spikes (2006) Epilepsia, 47, pp. 343-354Mintzer, S., Cendes, F., Soss, J., Andermann, F., Engel Jr, J., Dubeau, F., Unilateral hippocampal sclerosis with contralateral temporal scalp ictal onset (2004) Epilepsia, 45, pp. 792-80

Relationship between type of unprovoked venous thromboembolism and cancer location: An individual patient data meta-analysis

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