293 research outputs found
Yacht Single Window: A case for a vessel-to-infrastructure interaction platform
open8noOne of the most important and promising application of the IoT technologies is in the interaction of "mobile" entities, like cars and trucks, with "static" infrastructures in which they are immersed and from which they depend, like motorways, parking sites, city facilities. This type of application is generally named "vehicle-to-infrastructure" communication. This paper describes the research outcomes of the Yacht Single Window (YSW) project that applied this paradigm to a new and different use case for the IoT: enabling the 'vessel-to-infrastructure' communication in order to exploit the IoT technologies for the benefits of the leisure boats and yachts security, safety and improved connection.openBaglietto, Pierpaolo; Camera, Giancarlo; Maresca, Massimo; Gelli, Stefano; Parodi, Andrea; Serratore, Matteo; Roncarolo, Leonardo; Stasi, NicolaBaglietto, Pierpaolo; Camera, Giancarlo; Maresca, Massimo; Gelli, Stefano; Parodi, Andrea; Serratore, Matteo; Roncarolo, Leonardo; Stasi, Nicol
Design and Validation with Measurements of the LEIR Injection Line
The CERN Low Energy Ion Ring (LEIR) commissioning started in the year 2005. O4+and Pb54+ion beams are transferred at 4.2 MeV/nucleon from Linac 3 to LEIR through a low energy transfer line, for which the constraints and the resulting optics design are presented. First trajectory and dispersion measurements agreed only poorly with the theoretical model. Iterations of a refined optics model and further measurements improved the agreement between experimental observations and expectations. In particular, the effect of quadrupole errors in the line dipole magnets is discussed
Defective FoxP3+ Treg cell differentiation in the gut of Type 1 Diabetic patients
Environmental factors that act at the intestinal level such as diet, drugs, and microflora have a high impact on the pathogenesis of autoimmune Type 1 Diabetes (T1D), but it is still unclear how the gut milieu affects autoimmunity outside the intestine. Here we show that peripheral FoxP3+ Treg cell differentiation, a mechanism that takes place in the gut and is crucial to maintain systemic immune tolerance, is impaired in T1D patients. These results provide the first evidence that gut mucosa alteration could predispose to autoimmune T1D by affecting systemic immune regulation
First Beam Based Aperture Measurements in the Arcs of the CERN Large Hadron Collider
The LHC injection tests performed in August and early September 2008 in preparation for the circulating beam operation provided the first opportunity to measure with beam the mechanical aperture in two LHC sectors (2-3 and 7- 8). The aperture was probed by exciting free oscillations and local orbit bumps of the injected beam trajectories. Intensities of a few 109 protons were used to remain safely below the quench limit of superconductingmagnets in case of beam losses. The methods used to measure the mechanical aperture, the available on-line tools, and beam measurements for both sectors are presented. Detailed comparisons with the expected results from the as-built aperture models are also presented. It is shown that the measurements results are in good agreement with the LHC design aperture
Evidence of a role for Th17 cells in the breach of immune tolerance in arthritis
Th17 cells are thought to play a pathogenic role in various autoimmune diseases. Cytokines secreted by Th17 cells like IL-17, IL-17F and IL-22 have the capacity to mediate a massive inflammatory response. These proinflammatroy cytokines are likely to mediate the pathogenic potential of Th17 cells. Recent evidence suggests a role for Th17 cells in the breach of immune tolerance. This might shed some new light on the pathogenic role of Th17 cells in autoimmunity
Measurement of the longitudinal and transverse impedance of kicker magnets using the coaxial wire method
Fast kicker magnets are used to inject beam into and eject beam out of the CERN SPS accelerator ring. These kickers are generally ferrite loaded transmission line type magnets with a rectangular shaped aperture through which the beam passes. Unless special precautions are taken the impedance of the ferrite yoke can provoke significant beam induced heating, even above the Curie temperature of ferrite. In addition the impedance can contribute to beam instabilities. In this paper different variants of the coaxial wire method, both for measuring longitudinal and transverse impedance, are briefly discussed in a tutorial manner and do's and don'ts are shown on practical examples. In addition we present the results of several impedance measurements for SPS kickers using the wire method and compare those results with theoretical models
What\u27s at Stake: Is it a Vampire or a Virus?
Vampires have been discussed for millennia, appearing in folklore throughout various cultures. From the Egyptians and the Chinese to the Slavs, there have been numerous iterations of these bloodsucking fiends, but do their characteristics have any basis in fact, perhaps predicated upon misunderstandings of certain diseases?Using medical journals to discern plausible diseases for obscure and typical vampire traits, this paper functions on two levels. On one hand, it offers a repository of medical information for researchers who may want to delve further into the interdisciplinary field of pathology and folklore, especially where vampires of Western culture are concerned. On the other hand, it offers visual popular culture sources to serve as examples for each trait/disease, seeing as pop culture is where many people, myself included, get their ideas and renderings of vampires. Technology and medicine have advanced considerably since bloody, bloated corpses were mistaken as vampires, but some traits—eye color, charisma, allure, and fangs, among others—of certain, often diseased individuals could still be traced back to a vampiric condition.Faculty Sponsor: Dr. Gregory Brow
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