Reducing errors in guided implant surgery to optimize treatment outcomes.

Clinical considerations and treatment criteria in implant placement are constantly evolving. Prosthetically driven implant surgery has become the standard of care to improve short and long-term functional and esthetic outcomes. Therefore, implant position and angulation are planned according to the available bone, anatomical structures, and the requirements of the future prosthetic superstructure. In parallel with these developments, significant progress has been made in data imaging and different software technologies to allow the integration of data within a digital file format. Digitalization in implant surgery enables optimal planning of implant position, as well as the ability to transfer this planning to the surgical field-a process defined as "computer-supported implant planning and guided surgery." The aims of the present review are as follows: (a) to critically appraise the indications and potential "added value" of guided implant surgery, elaborating the main differences between dynamic and static guidance; and (b) to discuss the most important clinical considerations relevant for the different steps of the workflow that might influence the surgical outcome and to offer recommendations on how to avoid or reduce process errors in order to optimize treatment outcomes

Prediction Along a Developmental Perspective in Psychiatry: How Far Might We Go?

Most mental disorders originate in childhood, and once symptoms present, a variety of psychosocial and cognitive maladjustments may arise. Although early childhood problems are generally associated with later mental health impairments and psychopathology, pluripotent transdiagnostic trajectories may manifest. Possible predictors range from behavioral and neurobiological mechanisms, genetic predispositions, environmental and social factors, and psychopathological comorbidity. They may manifest in altered neurodevelopmental trajectories and need to be validated capitalizing on large-scale multi-modal epidemiological longitudinal cohorts. Moreover, clinical and etiological variability between patients with the same disorders represents a major obstacle to develop effective treatments. Hence, in order to achieve stratification of patient samples opening the avenue of adapting and optimizing treatment for the individual, there is a need to integrate data from multi-dimensionally phenotyped clinical cohorts and cross-validate them with epidemiological cohort data. In the present review, we discuss these aspects in the context of externalizing and internalizing disorders summarizing the current state of knowledge, obstacles, and pitfalls. Although a large number of studies have already increased our understanding on neuropsychobiological mechanisms of mental disorders, it became also clear that this knowledge might only be the tip of the Eisberg and that a large proportion still remains unknown. We discuss prediction strategies and how the integration of different factors and methods may provide useful contributions to research and at the same time may inform prevention and intervention

Protest event data for Croatia, Portugal, Serbia and Spain: Focus on strike data

‘Disobedient Democracy: A Comparative Analysis of Contentious Politics in the European Semi-periphery’ is a research project implemented by the Faculty of Political Science of the University of Zagreb, in the period 2016-2021, led by Principal Investigator Danijela Dolenec and funded by the Swiss National Science Foundation (IZ11Z0_166540 – PROMYS). The overall objective of the project is to explore how protest politics advances democracy by collecting and analyzing data on protest mobilizations in four countries: Portugal, Spain, Croatia and Serbia.‎info:eu-repo/semantics/publishedVersio

Tissue Reactions to Various Suture Materials Used in Oral Surgical Interventions

A variety of suture materials are available for primary wound closure following oral surgical procedures. The aim was to review the tissue reactions to the various suture materials used in oral surgical interventions. Databases were searched using the following keywords: cotton, nylon, polyglecaprone 25, polytetrafluoroethylene (ePTFE), Polyglactin 910, polyglycolic acid (PGA), polylactic acid, silk, surgery, suture, and tissue reaction. Articles published only in English language were included. Seventeen studies were included. Two studies reported that polyglecaprone 25 had positive effects on wound-healing as compared to silk. Six studies reported that silk elicits more intense tissue inflammatory response and delayed wound healing as compared to other suture materials (including ePTFE, polyglecaprone-25, PGA, and nylon). Polyglactin 910 sutures were associated with the development of stitch abscess in one clinical study. Eight studies reported that tissue reactions are minimal with nylon sutures. Tissue reactions to suture materials used for oral surgical interventions may vary depending on the surface properties and bacterial adherence properties of the material

Histologic and histomorphometric evaluation of peri-implant bone subjected to immediate loading: An experimental study with Macaca fascicularis

Purpose: Immediately loaded splinted implants can become osseointegrated when they are placed in the anterior part of the mandible. The concept of immediate loading has not been well examined in the posterior mandible. The aim of this study was to evaluate the hard tissue reactions around immediately loaded implants placed in the posterior mandible in the monkey model. Materials and Methods: Six adult M. fascicularis monkeys were used in this study. Thirty-six Ankylos implants (Degussa Dental, Hanau-Wolfgang, Germany) were placed after extraction of the second premolar, first, and second molar teeth and complete healing of the sockets. Control (C) group implants were placed and, after osseointegration, were loaded for 1 month using temporary acrylic resin prostheses and later for 2 months using splinted metal crowns. In the contralateral region of the mandible, test (T) group implants were placed and loaded immediately with the same sequence as carried out for the C implants. After sacrifice of the animals, specimens were examined histologically and evaluated histomorphometrically. Results: All implants were osseointegrated. Compact, cortical bone In contact with the implant surface without any gaps or connective tissue formation was demonstrated. Discussion: Histomorphometric findings of the bone-implant-contacts showed no significant differences between the T and C group implants. Peri-implant mineralized bone areas presented statistically significant differences and showed a higher density of bone between the threads of immediately loaded implants (P < .05). Conclusions: Immediately loaded splinted implants in the posterior mandible can become osseointegrated with a hard tissue peri-implant response similar to that of delayed loaded implants. Moreover, immediate loading seems to increase the ossification of the alveolar bone around endosseous implants. This record was migrated from the OpenDepot repository service in June, 2017 before shutting down

Protest cycles and democracy: a comparison between Portugal and Spain, 2000-2019

Neste artigo, são descritos e analisados os ciclos de protesto em Portugal e Espanha no início do século XXI. Considerando que a possibilidade de exercer o direito à dissensão na esfera pública constitui não apenas um dos elementos caraterizadores da democracia, mas igualmente um fator do seu fortalecimento, esta análise compara os ciclos de protesto nos dois países da Península Ibérica, atentando à sua magnitude, complexidade organizacional e aos seus aspetos culturais, em particular os repertórios de ação coletiva. Este estudo permite identificar diferentes tendências do protesto nos dois países, não obstante a Grande Recessão constituir, em ambos os casos, um marco inquestionável em termos da dimensão do protesto. Permite igualmente aferir da constante importância de atores de protesto tradicionais em Portugal, como os sindicatos, associada à existência de uma cultura de protesto mais democrática. Em contrapartida, em Espanha, a arena do protesto é mais variada e inovadora, mas também mais polarizada e conflitual.info:eu-repo/semantics/publishedVersio

Comparison of Two Differently Processed Acellular Dermal Matrix Products for Root Coverage Procedures: A Prospective, Randomized Multicenter Study

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141116/1/jper1693-sup-0001.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/141116/2/jper1693.pd