3,565 research outputs found

    Invasive Weeds, Wildfire, and Rancher Decision Making in the Great Basin

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    In this article, a numerical stochastic dynamic programming model (SDP) is developed to characterize the decision problem of a rancher operating on rangelands in northern Nevada that are affected by invasive annual grasses and wildfire. The model incorporates decisions about herd size management of a cow-calf operation and fuels treatment to reduce the size of rangeland wildfires. Currently, high transactions costs to obtain permits to implement land treatments on federally-owned rangelands appear to limit rancher involvement. The results of the model suggest that ranch income motives alone are likely insufficient for private ranchers to adopt preventative land treatments. The current treatment cost ($20 per acre at the minimum) appears to be prohibitively expensive relative to the benefits derived from the treatments under the low-productivity, semi-arid rangeland conditions.stochastic dynamic programming, cow-calf operation, rangeland, ecosystem, Livestock Production/Industries, Resource /Energy Economics and Policy,

    Major abdominal surgery in Jehovah’s Witnesses

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    Introduction Patients who are Jehovah’s Witnesses pose difficult ethical and moral dilemmas for surgeons because of their refusal to receive blood and blood products. This article outlines the personal experiences of six Jehovah’s Witnesses who underwent major abdominal surgery at a single institution and also summarises the literature on the perioperative care of these patients. Methods The patients recorded their thoughts and the dilemmas they faced during their surgical journey. We also reviewed the recent literature on the ethical principles involved in treating such patients and strategies recommended to make surgery safer. Results All patients were supported in their decision making by the clinical team and the Hospital Liaison Committee for Jehovah’s Witnesses. The patients recognised the ethical and moral difficulties experienced by clinicians in this setting. However, they described taking strength from their belief in Jehovah. A multitude of techniques are available to minimise the risk associated with major surgery in Jehovah’s Witness patients, many of which have been adopted to minimise unnecessary use of blood products in general. Nevertheless, the risks of catastrophic haemorrhage and consequent mortality remain an unresolved issue for the treating team. Conclusions Respect for a patient’s autonomy in this setting is the overriding ethical principle, with detailed discussion forming an important part of the preparation of a Jehovah’s Witness for major abdominal surgery. Clinicians must be diligent in the documentation of the patient’s wishes to ensure all members of the team can abide by these

    Liquefaction Hazard Mitigation by Prefabricated Vertical Drains

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    Liquefaction has typically been mitigated by in-situ densification; however vertical composite drains offer the possibility of preventing liquefaction and associated settlement while reducing the cost and time required for treatment. Three case histories are presented which describe the use of vertical drains to mitigate liquefaction hazard and techniques to control the flow of water exiting the drains. In addition, results from a test case are presented where controlled blasting techniques were used to evaluate drain performance in-situ. Blasting was successful in liquefying loose sand in an untreated test site. Similar blast charges were then detonated at adjacent sites treated with drains. Measurements demonstrated that the drains significantly increased the rate of pore pressure dissipation. In addition, the installation process typically densified the surrounding soil, thereby decreasing the liquefaction potential. Computer analyses successfully matched the measured response and suggest that the drains could be effective for earthquake events

    Development of a lightweight cryogenic insulating system Final report, 30 Jun. 1964 - 31 May 1966

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    Lightweight external panel insulation systems for thermal protection of cryogenic launch vehicle propellant tank

    Benefits of Artificially Generated Gravity Gradients for Interferometric Gravitational-Wave Detectors

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    We present an approach to experimentally evaluate gravity gradient noise, a potentially limiting noise source in advanced interferometric gravitational wave (GW) detectors. In addition, the method can be used to provide sub-percent calibration in phase and amplitude of modern interferometric GW detectors. Knowledge of calibration to such certainties shall enhance the scientific output of the instruments in case of an eventual detection of GWs. The method relies on a rotating symmetrical two-body mass, a Dynamic gravity Field Generator (DFG). The placement of the DFG in the proximity of one of the interferometer's suspended test masses generates a change in the local gravitational field detectable with current interferometric GW detectors.Comment: 16 pages, 4 figure

    ixpeobssim: a Simulation and Analysis Framework for the Imaging X-ray Polarimetry Explorer

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    ixpeobssim is a simulation and analysis framework, based on the Python programming language and the associated scientific ecosystem, specifically developed for the Imaging X-ray Polarimetry Explorer (IXPE). Given a source model and the response functions of the telescopes, it is designed to produce realistic simulated observations, in the form of event lists in FITS format, containing a strict super-set of the information provided by standard IXPE level-2 files. The core ixpeobssim simulation capabilities are complemented by a full suite of post-processing applications, allowing for the implementation of complex, polarization-aware analysis pipelines, and facilitating the inter-operation with the standard visualization and analysis tools traditionally in use by the X-ray community. We emphasize that, although a significant part of the framework is specific to IXPE, the modular nature of the underlying implementation makes it potentially straightforward to adapt it to different missions with polarization capabilities.Comment: 12 pages, 6 figures. Accepted for publication on SoftwareX; source code available at https://github.com/lucabaldini/ixpeobssi

    Heat and water transport in soils and across the soil-atmosphere interface: 1. Theory and different model concepts

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    Evaporation is an important component of the soil water balance. It is composed of water flow and transport processes in a porous medium that are coupled with heat fluxes and free air flow. This work provides a comprehensive review of model concepts used in different research fields to describe evaporation. Concepts range from nonisothermal two-phase flow, two-component transport in the porous medium that is coupled with one-phase flow, two-component transport in the free air flow to isothermal liquid water flow in the porous medium with upper boundary conditions defined by a potential evaporation flux when available energy and transfer to the free airflow are limiting or by a critical threshold water pressure when soil water availability is limiting. The latter approach corresponds with the classical Richards equation with mixed boundary conditions. We compare the different approaches on a theoretical level by identifying the underlying simplifications that are made for the different compartments of the system: porous medium, free flow and their interface, and by discussing how processes not explicitly considered are parameterized. Simplifications can be grouped into three sets depending on whether lateral variations in vertical fluxes are considered, whether flow and transport in the air phase in the porous medium are considered, and depending on how the interaction at the interface between the free flow and the porous medium is represented. The consequences of the simplifications are illustrated by numerical simulations in an accompanying paper

    Identifying chemokines as therapeutic targets in renal disease: Lessons from antagonist studies and knockout mice

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    Chemokines, in concert with cytokines and adhesion molecules, play multiple roles in local and systemic immune responses. In the kidney, the temporal and spatial expression of chemokines correlates with local renal damage and accumulation of chemokine receptor-bearing leukocytes. Chemokines play important roles in leukocyte trafficking and blocking chemokines can effectively reduce renal leukocyte recruitment and subsequent renal damage. However, recent data indicate that blocking chemokine or chemokine receptor activity in renal disease may also exacerbate renal inflammation under certain conditions. An increasing amount of data indicates additional roles of chemokines in the regulation of innate and adaptive immune responses, which may adversively affect the outcome of interventional studies. This review summarizes available in vivo studies on the blockade of chemokines and chemokine receptors in kidney diseases, with a special focus on the therapeutic potential of anti-chemokine strategies, including potential side effects, in renal disease. Copyright (C) 2004 S. Karger AG, Basel
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