29 research outputs found

    Determinants of Bone and Blood Lead Levels among Minorities Living in the Boston Area

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    We measured blood and bone lead levels among minority individuals who live in some of Boston’s neighborhoods with high minority representation. Compared with samples of predominantly white subjects we had studied before, the 84 volunteers in this study (33:67 male:female ratio; 31–72 years of age) had similar educational, occupational, and smoking profiles and mean blood, tibia, and patella lead levels (3 μg/dL, 11.9 μg/g, and 14.2 μg/g, respectively) that were also similar. The slopes of the univariate regressions of blood, tibia, and patella lead versus age were 0.10 μg/dL/year (p < 0.001), 0.45 μg/g/year (p < 0.001), and 0.73 μg/g/year (p < 0.001), respectively. Analyses of smoothing curves and regression lines for tibia and patella lead suggested an inflection point at 55 years of age, with slopes for subjects ≥ 55 years of age that were not only steeper than those of younger subjects but also substantially steeper than those observed for individuals > 55 years of age in studies of predominantly white participants. This apparent racial disparity at older ages may be related to differences in historic occupational and/or environmental exposures, or possibly the lower rates of bone turnover that are known to occur in postmenopausal black women. The higher levels of lead accumulation seen in this age group are of concern because such levels have been shown in other studies to predict elevated risks of chronic disease such as hypertension and cognitive dysfunction. Additional research on bone lead levels in minorities and their socioeconomic and racial determinants is needed

    Defining a common set of indicators to monitor road accidents in the European Union

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    BACKGROUND: currently road accidents are mostly monitored through mortality and injury rates. This paper reports the methodology and the results of a project set forth by the European Union (EU) and coordinated by the WHO aimed at identifying and evaluating a core set of indicators to monitor the causal chain of road accident health effects. The project is part of the ECOEHIS (Development of Environment and Health Indicators for European Union Countries). METHODS: a group of experts (WG), identified 14 indicators after a review of the information collected at the EU level, each of them representing a specific aspect of the DPSEEA (Driving, Pressure, State, Exposure, Effect, Action) model applied and adapted to the road accidents. Each indicator was scored according to a list of 16 criteria chosen by the WG. Those found to have a high score were analysed to determine if they were compatible with EU legislation and then tested in the feasibility study. RESULTS: 11 of the 14 indicators found to be relevant and compatible with the criteria of selection were proposed for the feasibility study. Mortality, injury, road accident rate, age of vehicle fleet, and distance travelled are the indicators recommended for immediate implementation. CONCLUSION: after overcoming the limitations that emerged (absence of a common definition of death by road accident and injury severity, underestimation of injuries, differences in information quality) this core set of indicators will allow Member States to carry out effective internal/external comparisons over time

    Summary of night noise guidelines for Europe

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    Considering the scientific evidence on the threshold of night noise exposure indicated by L night as defined in the Environmental Noise Directive (2002/49/EC), L night value of 40 dB should be the target of the night noise guideline (NNG) to protect the public, including the most vulnerable groups such as children, the chronically ill and the elderly. L night value of 55 dB is recommended as an interim target for countries which cannot follow NNG in the short term for various reasons and where policy-makers choose to adopt a stepwise approach. These guidelines may be considered an extension to the previous World Health Organization (WHO) guidelines for community noise (1999)

    Preparation of guidance for health risk assessment of environmental noise

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    In recent years, evidence has accumulated regarding health effects of environmental noise. The WHO European Centre for Environment and Health, Bonn, has organized several meetings of experts over recent years to examine the current state of knowledge, and to further develop approaches for quantifying the effect of noise on health. The outcomes of these meetings are being prepared as an initial guidance document on risk assessment of environmental noise¿quantitative risk assessments based on EBD (environmental burden of disease) methodology and the metric Disability-Adjusted Life Years (DALY). The target audience is primarily policy makers and their technical advisers who need to evaluate the issue of environmental noise in their jurisdictions. This document will provide synthesized reviews of various health effects of environmental noise (cardiovascular disease, cognitive impairment, sleep disturbance, annoyance, hearing impairment and tinnitus), and exemplary estimates, where possible, of the burden of the health outcomes of environmental noise based on exposure-response relationships, exposure prevalence, and disability weights. This paper describes the work that has been undertaken to prepare the guidance, and the structure of each chapter that deals with a particular health outcome: summary of evidence linking noise with the outcome; sources and assumptions regarding the exposure-response relationship and suggested disability weights; and current uncertainties, limitations and challenges regarding risk assessment of that health outcome.JRC.I.1-Chemical Assessment and Testin
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