Fast Mid-IR Flashes Detected During Small Solar X-Ray Bursts

Solar observations in the mid-infrared 8-14 \mu\m band continuum were carried out with cadence of 5 frames per second, in December 2007. Rapid small heated sources, with typical duration of the order of seconds, were found on the bright plage-like areas around sunspots, in association with relatively weak GOES soft X-ray bursts. This work presents the analysis of fast mid-infrared flashes detected during a GOES B2.0-class event on 10 December 2007, beginning at about 10:40 UT. Rapid brightness temperature enhancements of 0.5 to 2.0 K were detected at the Earth by a microbolometer array, using a telescope with 10.5 cm diameter aperture producing a diffraction limited field-of-view of 25 arcsec. Minimum detectable temperature change was of 0.1 K. The corresponding fluxes are 30-130 solar flux units. At the solar surface the estimated rapid brightenings were of 50-150 KComment: 12 pages including 6 figures. Accepted by Solar Physics, April 201

Desempenho de cordeiros de dois grupos genéticos terminados em confinamento no semiárido Nordestino.

Resumo: Com o objetivo de avaliar o desempenho de cordeiros mestiços oriundos do cruzamento de ovelhas sem raça definida (SRD) com reprodutores das raças deslanadas Santa Inês e Somalis Brasileira, foi realizado um experimento nas instalações da Embrapa caprinos e ovinos. Foi utilizado um total de 16 cordeiros machos inteiros, com peso vivo inicial médio de 19,688kg ao início do experimento distribuídos em um delineamento de bloco ao acaso e confinados em baias coletivas. Cordeiros mestiços Santa Inês apresentaram maior, ganho de peso médio diário (156g/dia) e ganho de peso total (8,900 kg) (P<0,05) que os mestiços Somalis (124g/dia e 7,088 kg, respectivamente). Entretanto a condição corporal inicial e final foi maior para os cordeiros mestiços Somalis (3,13 e 4,00 respectivamente). Os resultados permitem concluir que os carneiros da raça Santa Inês apresentam maiores vantagens que os Somalis quando utilizados em cruzamento com ovelhas deslanadas SRD no Nordeste brasileiro, pelo maior desenvolvimento em relação a ganho de peso principalmente. Performance of lambs of two genetic groups feedlot in northeastern semiarid. Abstract: Aiming to evaluate the performance of crossbred lambs from crossing sheep breed (SRD) with breeding breeds wooless Santa Ines and Brazilian Somalis, an experiment was conducted at Embrapa installation of goats and sheep. We used a total of 16 lambs, with initial weight of 19.688 kg at the beginning of the experiment distributed in a randomized block design and housed in collective pens. Santa Inês crossbred lambs had greater average daily weight gain (156g/dia) and total weight gain (8.900 kg) (P <0.05) than the mestizos Somalis (124g/dia and 7.088 kg, respectively). Meanwhile the initial and final body condition was higher for crossbred lambs Somalis (3.13 and 4.00 respectively). The results indicate that the Santa Inês sheep have greater advantages than the Somalis when used in cross ewes with SRD in northeast Brazil, the largest development in relation to weight gain especially

International multicenter observational study on assessment of ventilatory management during general anaesthesia for robotic surgery and its effects on postoperative pulmonary complication (AVATaR) : study protocol and statistical analysis plan

Introduction: Robotic-assisted surgery (RAS) has emerged as an alternative minimally invasive surgical option. Despite its growing applicability, the frequent need for pneumoperitoneum and Trendelenburg position could significantly affect respiratory mechanics during RAS. AVATaR is an international multicenter observational study aiming to assess the incidence of postoperative pulmonary complications (PPC), to characterise current practices of mechanical ventilation (MV) and to evaluate a possible association between ventilatory parameters and PPC in patients undergoing RAS. Methods and analysis: AVATaR is an observational study of surgical patients undergoing MV for general anaesthesia for RAS. The primary outcome is the incidence of PPC during the first five postoperative days. Secondary outcomes include practice of MV, effect of surgical positioning on MV, effect of MV on clinical outcome and intraoperative complications. Ethics and dissemination: This study was approved by the Institutional Review Board of the Hospital Israelita Albert Einstein. The study results will be published in peer-reviewed journals and disseminated at international conferences. Trial registration number: NCT02989415; Pre-results

Measurement of the cosmic ray spectrum above 4×10184{\times}10^{18} eV using inclined events detected with the Pierre Auger Observatory

A measurement of the cosmic-ray spectrum for energies exceeding $4{\times}10^{18}$ eV is presented, which is based on the analysis of showers with zenith angles greater than $60^{\circ}$ detected with the Pierre Auger Observatory between 1 January 2004 and 31 December 2013. The measured spectrum confirms a flux suppression at the highest energies. Above $5.3{\times}10^{18}$ eV, the "ankle", the flux can be described by a power law $E^{-\gamma}$ with index $\gamma=2.70 \pm 0.02 \,\text{(stat)} \pm 0.1\,\text{(sys)}$ followed by a smooth suppression region. For the energy ($E_\text{s}$) at which the spectral flux has fallen to one-half of its extrapolated value in the absence of suppression, we find $E_\text{s}=(5.12\pm0.25\,\text{(stat)}^{+1.0}_{-1.2}\,\text{(sys)}){\times}10^{19}$ eV.Comment: Replaced with published version. Added journal reference and DO

Energy Estimation of Cosmic Rays with the Engineering Radio Array of the Pierre Auger Observatory

The Auger Engineering Radio Array (AERA) is part of the Pierre Auger Observatory and is used to detect the radio emission of cosmic-ray air showers. These observations are compared to the data of the surface detector stations of the Observatory, which provide well-calibrated information on the cosmic-ray energies and arrival directions. The response of the radio stations in the 30 to 80 MHz regime has been thoroughly calibrated to enable the reconstruction of the incoming electric field. For the latter, the energy deposit per area is determined from the radio pulses at each observer position and is interpolated using a two-dimensional function that takes into account signal asymmetries due to interference between the geomagnetic and charge-excess emission components. The spatial integral over the signal distribution gives a direct measurement of the energy transferred from the primary cosmic ray into radio emission in the AERA frequency range. We measure 15.8 MeV of radiation energy for a 1 EeV air shower arriving perpendicularly to the geomagnetic field. This radiation energy -- corrected for geometrical effects -- is used as a cosmic-ray energy estimator. Performing an absolute energy calibration against the surface-detector information, we observe that this radio-energy estimator scales quadratically with the cosmic-ray energy as expected for coherent emission. We find an energy resolution of the radio reconstruction of 22% for the data set and 17% for a high-quality subset containing only events with at least five radio stations with signal.Comment: Replaced with published version. Added journal reference and DO

Measurement of the Radiation Energy in the Radio Signal of Extensive Air Showers as a Universal Estimator of Cosmic-Ray Energy

We measure the energy emitted by extensive air showers in the form of radio emission in the frequency range from 30 to 80 MHz. Exploiting the accurate energy scale of the Pierre Auger Observatory, we obtain a radiation energy of 15.8 \pm 0.7 (stat) \pm 6.7 (sys) MeV for cosmic rays with an energy of 1 EeV arriving perpendicularly to a geomagnetic field of 0.24 G, scaling quadratically with the cosmic-ray energy. A comparison with predictions from state-of-the-art first-principle calculations shows agreement with our measurement. The radiation energy provides direct access to the calorimetric energy in the electromagnetic cascade of extensive air showers. Comparison with our result thus allows the direct calibration of any cosmic-ray radio detector against the well-established energy scale of the Pierre Auger Observatory.Comment: Replaced with published version. Added journal reference and DOI. Supplemental material in the ancillary file

Identification of constrained sequence elements across 239 primate genomes

Noncoding DNA is central to our understanding of human gene regulation and complex diseases1,2, and measuring the evolutionary sequence constraint can establish the functional relevance of putative regulatory elements in the human genome3–9. Identifying the genomic elements that have become constrained specifically in primates has been hampered by the faster evolution of noncoding DNA compared to protein-coding DNA10, the relatively short timescales separating primate species11, and the previously limited availability of whole-genome sequences12. Here we construct a whole-genome alignment of 239 species, representing nearly half of all extant species in the primate order. Using this resource, we identified human regulatory elements that are under selective constraint across primates and other mammals at a 5% false discovery rate. We detected 111,318 DNase I hypersensitivity sites and 267,410 transcription factor binding sites that are constrained specifically in primates but not across other placental mammals and validate their cis-regulatory effects on gene expression. These regulatory elements are enriched for human genetic variants that affect gene expression and complex traits and diseases. Our results highlight the important role of recent evolution in regulatory sequence elements differentiating primates, including humans, from other placental mammals