4,374 research outputs found
Topological defects and misfit strain in magnetic stripe domains of lateral multilayers with perpendicular magnetic anisotropy
Stripe domains are studied in perpendicular magnetic anisotropy films
nanostructured with a periodic thickness modulation that induces the lateral
modulation of both stripe periods and inplane magnetization. The resulting
system is the 2D equivalent of a strained superlattice with properties
controlled by interfacial misfit strain within the magnetic stripe structure
and shape anisotropy. This allows us to observe, experimentally for the first
time, the continuous structural transformation of a grain boundary in this 2D
magnetic crystal in the whole angular range. The magnetization reversal process
can be tailored through the effect of misfit strain due to the coupling between
disclinations in the magnetic stripe pattern and domain walls in the in-plane
magnetization configuration
Controlled nucleation of topological defects in the stripe domain patterns of Lateral multilayers with Perpendicular Magnetic Anisotropy: competition between magnetostatic, exchange and misfit interactions
Magnetic lateral multilayers have been fabricated on weak perpendicular
magnetic anisotropy amorphous Nd-Co films in order to perform a systematic
study on the conditions for controlled nucleation of topological defects within
their magnetic stripe domain pattern. A lateral thickness modulation of period
is defined on the nanostructured samples that, in turn, induces a lateral
modulation of both magnetic stripe domain periods and average
in-plane magnetization component . Depending on lateral multilayer
period and in-plane applied field, thin and thick regions switch independently
during in-plane magnetization reversal and domain walls are created within the
in-plane magnetization configuration coupled to variable angle grain boundaries
and disclinations within the magnetic stripe domain patterns. This process is
mainly driven by the competition between rotatable anisotropy (that couples the
magnetic stripe pattern to in-plane magnetization) and in-plane shape
anisotropy induced by the periodic thickness modulation. However, as the
structural period becomes comparable to magnetic stripe period ,
the nucleation of topological defects at the interfaces between thin and thick
regions is hindered by a size effect and stripe domains in the different
thickness regions become strongly coupled.Comment: 10 pages, 7 figures, submitted to Physical Review
Human myiasis in Ecuador.
We review epidemiological and clinical data on human myiasis from Ecuador, based on data from the Ministry of Public Health (MPH) and a review of the available literature for clinical cases. The larvae of four flies, Dermatobia hominis, Cochliomyia hominivorax, Sarcophaga haemorrhoidalis, and Lucilia eximia, were identified as the causative agents in 39 reported clinical cases. The obligate D. hominis, causing furuncular lesions, caused 17 (43.5%) cases distributed along the tropical Pacific coast and the Amazon regions. The facultative C. hominivorax was identified in 15 (38%) clinical cases, infesting wound and cavitary lesions including orbital, nasal, aural and vaginal, and occurred in both subtropical and Andean regions. C. hominivorax was also identified in a nosocomial hospital-acquired wound. Single infestations were reported for S. haemorrhoidalis and L. eximia. Of the 39 clinical cases, 8 (21%) occurred in tourists. Ivermectin, when it became available, was used to treat furuncular, wound, and cavitary lesions successfully. MPH data for 2013–2015 registered 2,187 cases of which 54% were reported in men; 46% occurred in the tropical Pacific coast, 30% in the temperate Andes, 24% in the tropical Amazon, and 0.2% in the Galapagos Islands. The highest annual incidence was reported in the Amazon (23 cases/100,000 population), followed by Coast (5.1/100,000) and Andes (4.7/100,000). Human myiasis is a neglected and understudied ectoparasitic infestation, being endemic in both temperate and tropical regions of Ecuador. Improved education and awareness among populations living in, visitors to, and health personnel working in high-risk regions, is required for improved epidemiological surveillance, prevention, and correct diagnosis and treatment
Parallel ant colony optimization for the training of cell signaling networks
[Abstract]: Acquiring a functional comprehension of the deregulation of cell signaling networks in disease allows progress in the development of new therapies and drugs. Computational models are becoming increasingly popular as a systematic tool to analyze the functioning of complex biochemical networks, such as those involved in cell signaling. CellNOpt is a framework to build predictive logic-based models of signaling pathways by training a prior knowledge network to biochemical data obtained from perturbation experiments. This training can be formulated as an optimization problem that can be solved using metaheuristics. However, the genetic algorithm used so far in CellNOpt presents limitations in terms of execution time and quality of solutions when applied to large instances. Thus, in order to overcome those issues, in this paper we propose the use of a method based on ant colony optimization, adapted to the problem at hand and parallelized using a hybrid approach. The performance of this novel method is illustrated with several challenging benchmark problems in the study of new therapies for liver cancer
Comercio Internacional y Competitividad del banano orgánico peruano 2008- 2015
La investigación tuvo como objetivo determinar el comercio internacional y la
competitividad del banano orgánico peruano durante el periodo 2008-2015.
El método desarrollado para la investigación es no experimental porque los datos
son ex post facto. Una vez recopilado los datos, los hemos organizado a través de
la agrupación por variables las cuales son: Comercio Internacional y
competitividad, considerando como dimensiones del Comercio Internacional las
exportaciones y las importaciones, y como indicadores valor, volumen y precio de
exportación y valor, volumen y precio de importación.
Para la variable competitividad se consideró como indicadores: Productividad y
costo unitario.
En conclusión de acuerdo con los resultados de la investigación realizada ha
quedado demostrado que la exportación del banano orgánico peruano, durante el
periodo 2008-2015, ha sido competitiva y, además, ha tenido tendencia positiva
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