10 research outputs found

    Desempeño y procesos gubernamentales

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    El texto que aquí se presenta, permite al lector reconocer distintas problemáticas de las administraciones públicas en diferentes vertientes, así como reconocer diagnósticos y alternativas de solución, acordes a la problemática planteada.El gobierno se materializa a través de la Administración Pública, opera por medio de dependencias y entidades adscritas al Poder Ejecutivo. Sus principales actividades están relacionadas con la planeación, la organización, la administración de recursos humanos, la dirección y el control. A partir de este planteamiento inicial, el libro que aquí se presenta La Administración Pública y el gobierno en México: desempeño y procesos gubernamentales pretende aportar al estudio de las administraciones públicas, a través del análisis del desempeño de los gobiernos, tanto en el ámbito federal, estatal y municipal

    Prospective individual patient data meta-analysis of two randomized trials on convalescent plasma for COVID-19 outpatients

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    Data on convalescent plasma (CP) treatment in COVID-19 outpatients are scarce. We aimed to assess whether CP administered during the first week of symptoms reduced the disease progression or risk of hospitalization of outpatients. Two multicenter, double-blind randomized trials (NCT04621123, NCT04589949) were merged with data pooling starting when = 50 years and symptomatic for <= 7days were included. The intervention consisted of 200-300mL of CP with a predefined minimum level of antibodies. Primary endpoints were a 5-point disease severity scale and a composite of hospitalization or death by 28 days. Amongst the 797 patients included, 390 received CP and 392 placebo; they had a median age of 58 years, 1 comorbidity, 5 days symptoms and 93% had negative IgG antibody-test. Seventy-four patients were hospitalized, 6 required mechanical ventilation and 3 died. The odds ratio (OR) of CP for improved disease severity scale was 0.936 (credible interval (CI) 0.667-1.311); OR for hospitalization or death was 0.919 (CI 0.592-1.416). CP effect on hospital admission or death was largest in patients with <= 5 days of symptoms (OR 0.658, 95%CI 0.394-1.085). CP did not decrease the time to full symptom resolution

    Untangling the Sources of Abundance Dispersion in Low-metallicity Stars

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    We measure abundances of 12 elements (Na, Mg, Si, Ca, Sc, Ti, V, Cr, Mn, Fe, Co, Ni) in a sample of 86 metal-poor (−2 ≲ [Fe/H] ≲ −1) subgiant stars in the solar neighborhood. Abundances are derived from high-resolution spectra taken with the Potsdam Echelle Polarimetric and Spectroscopic Instrument on the Large Binocular Telescope, modeled using iSpec and MOOG. By carefully quantifying the impact of photon-noise (<0.05 dex for all elements), we robustly measure the intrinsic scatter of abundance ratios. At fixed [Fe/H], the rms intrinsic scatter in [X/Fe] ranges from 0.04 (Cr) to 0.16 dex (Na), with a median of 0.08 dex. Scatter in [X/Mg] is similar, and accounting for [ α /Fe] only reduces the overall scatter moderately. We consider several possible origins of the intrinsic scatter with particular attention to fluctuations in the relative enrichment by core-collapse supernovae (CCSN) and Type Ia supernovae and stochastic sampling of the CCSN progenitor mass distribution. The stochastic sampling scenario provides a good quantitative explanation of our data if the effective number of CCSN contributing to the enrichment of a typical sample star is N ∼ 50. At the median metallicity of our sample, this interpretation implies that the CCSN ejecta are mixed over a gas mass ∼6 × 10 ^4 M _⊙ before forming stars. The scatter of elemental abundance ratios is a powerful diagnostic test for simulations of star formation, feedback, and gas mixing in the early phases of the Galaxy

    A Catalog of M-dwarf Flares with ASAS-SN

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    We analyzed the light curves of 1376 early-to-late, nearby M dwarfs to search for white-light flares using photometry from the All-Sky Automated Survey for Supernovae (ASAS-SN). We identified 480 M dwarfs with at least one potential flare employing a simple statistical algorithm that searches for sudden increases in VV-band flux. After more detailed evaluation, we identified 62 individual flares on 62 stars. The event amplitudes range from 0.12<ΔV<2.040.12 <\Delta V < 2.04 mag. Using classical-flare models, we place lower limits on the flare energies and obtain VV-band energies spanning 2.0×1030EV6.9×10352.0\times10^{30} \lesssim E_{V} \lesssim 6.9\times10^{35} erg. The fraction of flaring stars increases with spectral type, and most flaring stars show moderate to strong Hα\alpha emission. Additionally, we find that 14 of the 62 flaring stars are rotational variables, and they have shorter rotation periods and stronger Hα\alpha emission than non-flaring rotational variable M dwarfs.Comment: 16 pages, 5 figures, 7 tables, submitted to the AAS Journal

    Белым снегом

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    Белым снегом, белым снегом / Ночь метельная ту стежку замела, / По которой, по которой / Я с тобою, милый, рядышком прошла

    Connective tissue disease related interstitial lung diseases and idiopathic pulmonary fibrosis: provisional core sets of domains and instruments for use in clinical trials.

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    Analysis of Outcomes in Ischemic vs Nonischemic Cardiomyopathy in Patients With Atrial Fibrillation A Report From the GARFIELD-AF Registry

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    IMPORTANCE Congestive heart failure (CHF) is commonly associated with nonvalvular atrial fibrillation (AF), and their combination may affect treatment strategies and outcomes
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