Intrauterine undernutrition - renal and vascular origin of hypertension

A large number of clinical and experimental studies supports the hypothesis that intrauterine undernutrition is an important determinant of hypertension, coronary heart disease and non-insulin-dependent diabetes in the adult offspring. in this review, the renal and vascular repercussions of maternal undernutrition are emphasized, and the physiopatologic mechanisms discussed. the origin of hypertension is detailed based upon the findings of kidney functional parameters and endothelium function studies. A working model linking hypertension to intrauterine undernutrition is proposed. (C) 2003 European Society of Cardiology. Published by Elsevier B.V. All rights reserved.Univ São Paulo, ICB 1, Dept Farmacol, Lab Hipertensao, BR-05508900 São Paulo, SP, BrazilUniversidade Federal de São Paulo, São Paulo, SP, BrazilUniversidade Federal de São Paulo, São Paulo, SP, BrazilWeb of Scienc

Prevalence and risk factors for intestinal protozoa infection in elderly residents at Long Term Residency Institutions in Southeastern Brazil

This study determined the prevalence of intestinal protozoa in Long Term Residency Institutions for the Elderly (ILPI) in elders, nurses and food handlers, identifying the risk factors associated with the infections. Stool samples taken from the elderly (n = 293), nurses (63) and food handlers (19) were studied. Questionnaires were used with questions related to sociodemographic variables, health, behavior and health characteristics. Stool samples were examined using the techniques of Faust and Ziehl Neelsen, and the prevalence of G. duodenalis, Cryptosporidium spp., E. histolytica/dispar in the elderly was 4.0%, 1.0% and 0.3% respectively. Nurses and food handlers showed 4.8% and 5.2% positivity only for G. duodenalis, respectively. The origin of the individuals and contact with domestic animals has been associated with infection by G. duodenalis in the elderly, and contact with domestic animals was considered a risk factor for infection. The last stool examinations were related to Cryptosporidium spp.. None of the variables were associated with E. histolytica/dispar. The frequency of hand washing was significantly associated with G. duodenalis among nurses. The frequency of positive samples of G. duodenalis, Cryptosporidium spp., E. histolytica/dispar showed that ILPIs environments are conducive to this occurring due to contact between the elderly, nurses and food handlers, which are often poorly trained in hygiene procedures and food handling

Women's strategies for coping with urinary incontinence

RESUmo Este artigo é parte de uma pesquisa qualitativa mais abrangente que utilizou como referencial teórico-metodológico a Grounded Theory e o Interacionismo Simbólico, resultando no modelo teórico denominado "Entre o sofrimento e a esperança: a reabilitação da incontinência urinária como componente interveniente". Com a intenção de comunicar todo o conhecimento produzido, apresenta-se parte desse modelo, referente ao processo de enfrentamento da incontinência urinária por mulheres sem perspectivas de acesso ao tratamento cirúrgico, após falha dos procedimentos conservadores. Ao inter--relacionar os componentes (categorias e subcategorias) relativos à experiência dessas mulheres, buscando compará-los e analisá-los para compreender a interação entre eles, notou-se vulnerabilidade moral e psicossocial no movimento da experiên-cia do grupo, suscetibilizando-o a riscos à saúde e ao comprometimento da qualidade de vida. Pesquisas são necessárias para aprofundar a compreensão de experiên-cias em que haja barreira ao tratamento cirúrgico por descrédito do profissional médico sobre sua efetividade. Original article AbStRAct This article is part of a more comprehensive qualitative study which used grounded theory and symbolic interactionism as theoretical and methodological frameworks, resulting in the theoretical model entitled, Between suffering and hope: rehabilitation of urinary incontinence as an intervenient component. In order to communicate all the knowledge produced, part of this model is presented, and it refers to the process of coping with urinary incontinence by women without perspectives of access to surgical treatment after failure of conservative procedures. When interrelating the components (categories and subcategories) of these women's experience in order to compare and analyze them to understand their interaction, moral and psychosocial vulnerability were noticed within the experience of the group, which makes them susceptible to health risks and to compromise of their quality of life, observed in the movement of the group's experience. Research is needed to further understand experiences in which there are barriers to surgical treatment due to physicians' disbelief in its effectiveness. dEScRiPtoRS Urinary incontinence Women Rehabilitation Surgery Life change events RESUmEn El artículo forma parte de una investigación cualitativa más abarcadora que utilizó como referencial teórico-metodológico la Grounded Theory y el Interaccionismo Simbólico, resultando en el modelo teóri-co denominado "Entre el sufrimiento y la esperanza: la rehabilitación de la incontinencia urinaria como componente interviniente". Con intención de comunicar el conocimiento producido, se presenta parte de dicho modelo, referido al proceso de enfrentamiento de la incontinencia urinaria en mujeres sin perspectivas de acceso a tratamiento quirúrgico, habiendo fallado los procedimientos conservadores. Al interrelacionarse los componentes (categorías y subcategorías) relativos a la experiencia de dichas mujeres, buscando compararlos y analizarlos para entender su interacción, se notó vulnerabilidad moral y psicosocial en el tránsito de experiencia grupal, susceptibilizándolo a riesgos de salud y al compromiso de calidad de vida. Serán necesarias investigaciones que profundicen la comprensión de experiencias en las que existan obstáculos al tratamiento quirúrgi-co por descreer el profesional médico sobre su efectividad. dEScRiPtoRES Incontinencia urinaria Mujeres Rehabilitación Cirugía Acontecimientos que cambian la vid

Oxidative DNA damage in patients infected by Helicobacter pylori

Univ Estadual Paulista Julio Mesquita Filho, Fac Med, Dept Patol, Botucatu, SP, BrazilUniv Estadual Paulista Julio Mesquita Filho, Fac Med, Dept Patol, Botucatu, SP, Brazi