Microvascular cutaneous coverage in wounds that expose the Achilles tendon: case report

Achilles tendon rupture, being one of the main tendon ruptures present, surgery being the most favourable option even taking into account complications such as infections and skin necrosis, it is necessary to develop techniques which help to reduce complications and increase benefits. The methods follow-up of 2 cases of patients with skin defects in the region of the Achilles tendon in patients who were treated at the "Luis Guillermo lbarra lbarra" national rehabilitation institute during the period 2020-2021 in the Traumatology service, treated with radial free flap forearm, using the description of the most used flaps in the literature. Results in both cases integrity of the free radial forearm flap in its entirety, functional recovery for walking, ability to put shoes back on, and without the need for reoperation, as well as a high level of satisfaction by patients. Conclusions if we are talking about an Achilles tendon rupture with a significant skin defect, the free radial forearm flap is an adequate option, if we are talking about a complete defect, the composite flap is the best option, remember that the decision on what type of flap will be used will depend on of the size of the lesion

Walking family: Programme of parental skills during foster care and reunification. Summary of main findings of the Project I+D EDU2014-52921-C2. [Infographics]

Podeu consultar la versió castellana, francesa i portuguesa al recurs relacionat.Walking Family is a support programme for specific parenting skills in foster care and reunification. Its main aim is to promote the acceptance and involvement of the welfare measure and to foster and strengthen reunification. One of the most relevant aspects of the programme is its group methodology, as it can be used to convey effective coping strategies for everyday problems. Walking Family is characterised by three cornerstones of innovation: positive parenting and child welfare, child participation and family resilience. The programme is developed over 5 modules, each containing 3 sessions. Each session offers activities to do with the children, with the parents and with the family as a unit

Use of tocilizumab in kidney transplant recipients with COVID-1

Acute respiratory distress syndrome associated with coronavirus infection is related to a cytokine storm with large interleukin-6 (IL-6) release. The IL-6-receptor blocker tocilizumab may control the aberrant host immune response in patients with coronavirus disease 2019 (COVID-19) . In this pandemic, kidney transplant (KT) recipients are a high-risk population for severe infection and showed poor outcomes. We present a multicenter cohort study of 80 KT patients with severe COVID-19 treated with tocilizumab during hospital admission. High mortality rate was identified (32.5%), related with older age (hazard ratio [HR] 3.12 for those older than 60 years, P = .039). IL-6 and other inflammatory markers, including lactic acid dehydrogenase, ferritin, and D-dimer increased early after tocilizumab administration and their values were higher in nonsurvivors. Instead, C-reactive protein (CRP) levels decreased after tocilizumab, and this decrease positively correlated with survival (mean 12.3 mg/L in survivors vs. 33 mg/L in nonsurvivors). Each mg/L of CRP soon after tocilizumab increased the risk of death by 1% (HR 1.01 [confidence interval 1.004-1.024], P = .003). Although patients who died presented with worse respiratory situation at admission, this was not significantly different at tocilizumab administration and did not have an impact on outcome in the multivariate analysis. Tocilizumab may be effective in controlling cytokine storm in COVID-19 but randomized trials are needed

Latin Americans show wide-spread Converso ancestry and imprint of local Native ancestry on physical appearance

Historical records and genetic analyses indicate that Latin Americans trace their ancestry mainly to the intermixing (admixture) of Native Americans, Europeans and Sub-Saharan Africans. Using novel haplotype-based methods, here we infer sub-continental ancestry in over 6,500 Latin Americans and evaluate the impact of regional ancestry variation on physical appearance. We find that Native American ancestry components in Latin Americans correspond geographically to the present-day genetic structure of Native groups, and that sources of non-Native ancestry, and admixture timings, match documented migratory flows. We also detect South/East Mediterranean ancestry across Latin America, probably stemming mostly from the clandestine colonial migration of Christian converts of non-European origin (Conversos). Furthermore, we find that ancestry related to highland (Central Andean) versus lowland (Mapuche) Natives is associated with variation in facial features, particularly nose morphology, and detect significant differences in allele frequencies between these groups at loci previously associated with nose morphology in this sample.Instituto Multidisciplinario de Biología Celula

Latin Americans show wide-spread Converso ancestry and imprint of local Native ancestry on physical appearance

Historical records and genetic analyses indicate that Latin Americans trace their ancestry mainly to the intermixing (admixture) of Native Americans, Europeans and Sub-Saharan Africans. Using novel haplotype-based methods, here we infer sub-continental ancestry in over 6,500 Latin Americans and evaluate the impact of regional ancestry variation on physical appearance. We find that Native American ancestry components in Latin Americans correspond geographically to the present-day genetic structure of Native groups, and that sources of non-Native ancestry, and admixture timings, match documented migratory flows. We also detect South/East Mediterranean ancestry across Latin America, probably stemming mostly from the clandestine colonial migration of Christian converts of non-European origin (Conversos). Furthermore, we find that ancestry related to highland (Central Andean) versus lowland (Mapuche) Natives is associated with variation in facial features, particularly nose morphology, and detect significant differences in allele frequencies between these groups at loci previously associated with nose morphology in this sample.Instituto Multidisciplinario de Biología Celula

Caminhar em família: Programa de competências parentais durante o acolhimento e a reunificação familiar. Resumo dos principais resultados do Projeto I+D EDU2014-52921-C2. [Infográficos]

Podeu consultar la versió castellana, anglesa i francesa al recurs relacionat.Caminhar em familia é um programa de apoio às competências parentais específicas aos processos de acolhimento e de reunificação familiar. O seu principal objetivo é promover a aceitação e o envolvimento com a medida de proteção, bem como o de favorecer e consolidar a reunificação familiar. Um dos aspetos mais relevantes do programa é a sua metodologia grupal, já que através da mesma se transmitem estratégias eficazes para dar resposta aos problemas quotidianos. O Caminhar em família carateriza-se por três linhas de inovação: Parentalidade positiva e proteção à infância, participação infantil e resiliência familiar. O Programa desenvolve-se em 5 módulos e cada um deles inclui 3 sessões. Cada sessão apresenta atividades para realizar com filhos e filhas, com pais e mães e com a família em conjunto

Marcher en famille: Programme de compétences parentales pendant l'accueil et la réunification familiale. Résumé des principaux résultats du Projet I+D EDU2014-52921-C2. [Infographie]

Podeu consultar la versió castellana, anglesa i portuguesa al recurs relacionat.Marcher en famille est un programme de soutien aux compétences parentales spécifiques dans un processus d’accueil et de réunification familiale. Son objectif principal est de promouvoir l’acceptation et l’implication de la mesure de protection, ainsi que de favoriser et de garantir la réunification familiale. L’un des aspects les plus importants du programme est sa méthodologie groupale, puisque l’on peut au travers d’elle transmettre des stratégies effectives d’affrontement des problèmes quotidiens. Le Marcher en famille se caractérise par trois axes d’innovation: Parentalité positive et protection de l’enfance, participation infantile et résilience familiale. Le programme se développe en 5 modules et chacun d’entre eux comprend 3 séances. Chaque séance présente des activités à réaliser avec les fils

Caminar en familia: Programa de competencias parentales durante el acogimiento y la reunificación familiar. Resumen de los principales resultados del Proyecto I+D EDU2014-52921-C2. [Infografía]

Podeu consultar la versió anglesa, francesa i portuguesa al recurs relacionat.Caminar en familia es un programa de apoyo a las competencias parentales específicas en un proceso de acogida y de reunificación familiar. Su principal objetivo es promocionar la aceptación y la implicación de la medida de protección así como favorecer y afianzar la reunificación familiar. Uno de los aspectos más relevante del programa es su metodología grupal, ya que a través de ella se pueden transmitir estrategias efectivas de afrontamiento de los problemas cotidianos. El Caminar en familia se caracteriza por tres ejes de innovación: Parentalidad positiva y protección a la infancia, participación infantil y resiliencia familiar. El programa se desarrolla en 5 módulos y por cada uno de ellos contiene 3 sesiones. Cada sesión presenta actividades para realizar con los hijos e hijas, con los padres y madres y con la familia en su conjunto

Overview of recent TJ-II stellarator results

The main results obtained in the TJ-II stellarator in the last two years are reported. The most important topics investigated have been modelling and validation of impurity transport, validation of gyrokinetic simulations, turbulence characterisation, effect of magnetic configuration on transport, fuelling with pellet injection, fast particles and liquid metal plasma facing components. As regards impurity transport research, a number of working lines exploring several recently discovered effects have been developed: the effect of tangential drifts on stellarator neoclassical transport, the impurity flux driven by electric fields tangent to magnetic surfaces and attempts of experimental validation with Doppler reflectometry of the variation of the radial electric field on the flux surface. Concerning gyrokinetic simulations, two validation activities have been performed, the comparison with measurements of zonal flow relaxation in pellet-induced fast transients and the comparison with experimental poloidal variation of fluctuations amplitude. The impact of radial electric fields on turbulence spreading in the edge and scrape-off layer has been also experimentally characterized using a 2D Langmuir probe array. Another remarkable piece of work has been the investigation of the radial propagation of small temperature perturbations using transfer entropy. Research on the physics and modelling of plasma core fuelling with pellet and tracer-encapsulated solid-pellet injection has produced also relevant results. Neutral beam injection driven Alfvénic activity and its possible control by electron cyclotron current drive has been examined as well in TJ-II. Finally, recent results on alternative plasma facing components based on liquid metals are also presentedThis work has been carried out within the framework of the EUROfusion Consortium and has received funding from the Euratom research and training programme 2014–2018 under Grant Agreement No. 633053. It has been partially funded by the Ministerio de Ciencia, Inovación y Universidades of Spain under projects ENE2013-48109-P, ENE2015-70142-P and FIS2017-88892-P. It has also received funds from the Spanish Government via mobility grant PRX17/00425. The authors thankfully acknowledge the computer resources at MareNostrum and the technical support provided by the Barcelona S.C. It has been supported as well by The Science and Technology Center in Ukraine (STCU), Project P-507F