Statistical mechanics of the spherical hierarchical model with random fields

We study analytically the equilibrium properties of the spherical hierarchical model in the presence of random fields. The expression for the critical line separating a paramagnetic from a ferromagnetic phase is derived. The critical exponents characterising this phase transition are computed analytically and compared with those of the corresponding $D$-dimensional short-range model, leading to conclude that the usual mapping between one dimensional long-range models and $D$-dimensional short-range models holds exactly for this system, in contrast to models with Ising spins. Moreover, the critical exponents of the pure model and those of the random field model satisfy a relationship that mimics the dimensional reduction rule. The absence of a spin-glass phase is strongly supported by the local stability analysis of the replica symmetric saddle-point as well as by an independent computation of the free-energy using a renormalization-like approach. This latter result enlarges the class of random field models for which the spin-glass phase has been recently ruled out.Comment: 23 pages, 2 figure

Dar Al Gani 896: A unique picritic achondrite

Accepted versio

Surnames as Markers of Pathologies – Two Statistical Techniques and Their Applications

The objective of this research is to propose and to validate two different statistical techniques to test the hypothesis of an association between surnames and pathologies, in a population participating in a screening procedure for a given pathology. We propose two statistical methods: a first technique is based on the rarefaction method, and second one is based on the principle of resampling, and it can be considered a special case of a randomisation test. Both the techniques are applied to a data set of babies screened for congenital hypothyroidism (CH), and they gave similar results. The large overlapping of the results seems to suggest a substantial validity of the proposed techniques

Surnames as Markers of Pathologies – Two Statistical Techniques and Their Applications

The objective of this research is to propose and to validate two different statistical techniques to test the hypothesis of an association between surnames and pathologies, in a population participating in a screening procedure for a given pathology. We propose two statistical methods: a first technique is based on the rarefaction method, and second one is based on the principle of resampling, and it can be considered a special case of a randomisation test. Both the techniques are applied to a data set of babies screened for congenital hypothyroidism (CH), and they gave similar results. The large overlapping of the results seems to suggest a substantial validity of the proposed techniques

Effect of anthocyanin absence on white berry grape (Vitis vinifera L.)

In grapevines, white berried cultivars are characterized by the absence of anthocyanins, which are the main pigments in V. vinifera fruits. These varieties produce berries with a yellowish color. The pigments responsible of this hue are still not well defined. In this paper, spectrophotometric analyzes were carried out using non-invasive methods (reflectance spectra) and destructive quantifications (chlorophyll and carotenoid quantifications) to describe the variation in color of three white grape varieties during ripening. A decrease in chlorophylls and carotenoids was found. Changes in the proportion of blue (450-500 nm) and red (630\u2011700 nm) absorption bands were underlined. The contribution of melanin-like pigments (oxidation products) is also discussed. In general, our results indicate that the yellow color of white cultivars is not related to the activation of specific biosynthetic pathways. It is most likely due to a series of catabolic processes (and to their relative intensity), which become visible and that are possibly stimulated by the anthocyanin absence

Effect of anthocyanin absence on white berry grape (Vitis vinifera L.)

In grapevines, white berried cultivars are characterized by the absence of anthocyanins, which are the main pigments in V. vinifera fruits. These varieties produce berries with a yellowish color. The pigments responsible of this hue are still not well defined. In this paper, spectrophotometric analyzes were carried out using non-invasive methods (reflectance spectra) and destructive quantifications (chlorophyll and carotenoid quantifications) to describe the variation in color of three white grape varieties during ripening. A decrease in chlorophylls and carotenoids was found. Changes in the proportion of blue (450-500 nm) and red (630‑700 nm) absorption bands were underlined. The contribution of melanin-like pigments (oxidation products) is also discussed. In general, our results indicate that the yellow color of white cultivars is not related to the activation of specific biosynthetic pathways. It is most likely due to a series of catabolic processes (and to their relative intensity), which become visible and that are possibly stimulated by the anthocyanin absence

Chlorophyll and carotenoid quantifications in white grape (Vitis vinifera L.) skins by reflectance spectroscopy

In white grapes, chlorophylls and carotenoids play important roles in berry color and environmental interactions (e.g. radiative stresses). In this paper, easy, fast and low cost non-invasive reflectance methods have been tested and developed. Previously published indexes showed good performances for chlorophyll quantifications. However, in this work, new formulas able to discriminate chlorophylls a and b were also proposed. The wavelengths of major interest for the absorption detection were identified. Formulas based on the Gaussians half heights were proposed. In general, chlorophyll quantifications were obtained directly from reflectance spectra, while carotenoid absorption bands did not allow good reflectance correlations. However, the chlorophyll/carotenoid ratio (due to the pigments physiological linked roles) could be used to estimate carotenoid content. Their proportion changes during berry development, thus the index coefficients should be adapted in relation to the BBCH phenological phase. The obtained indexes demonstrated good correlations with the destructive quantifications. These methods could support further researches concerning cultivar classification and physiological studies

Observing without acting: a balance of excitation and suppression in the human corticospinal pathway

Transcranial magnetic stimulation (TMS) studies of human primary motor cortex (M1) indicate an increase corticospinal excitability during the observation of another's action. This appears to be somewhat at odds with recordings of pyramidal tract neurons in primate M1 showing that there is a balance of increased and decreased activity across the population. TMS is known to recruit a mixed population of cortical neurons, and so one explanation for previous results is that TMS tends to recruit those excitatory output neurons whose activity is increased during action observation. Here we took advantage of the directional sensitivity of TMS to recruit different subsets of M1 neurons and probed whether they responded differentially to action observation in a manner consistent with the balanced change in activity in primates. At the group level we did not observe the expected increase in corticospinal excitability for either TMS current direction during the observation of a precision grip movement. Instead, we observed substantial inter-individual variability ranging from strong facilitation to strong suppression of corticospinal excitability that was similar across both current directions. Thus, we found no evidence of any differential changes in the excitability of distinct M1 neuronal populations during action observation. The most notable change in corticospinal excitability at the group level was a general increase, across muscles and current directions, when participants went from a baseline state outside the task to a baseline state within the actual observation task. We attribute this to arousal- or attention-related processes, which appear to have a similar effect on the different corticospinal pathways targeted by different TMS current directions. Finally, this rather non-specific increase in corticospinal excitability suggests care should be taken when selecting a "baseline" state against which to compare changes during action observation

The Expanding Horizon of Neural Stimulation for Hyperkinetic Movement Disorders

Novel methods of neural stimulation are transforming the management of hyperkinetic movement disorders. In this review the diversity of approach available is showcased. We first describe the most commonly used features that can be extracted from oscillatory activity of the central nervous system, and how these can be combined with an expanding range of non-invasive and invasive brain stimulation techniques. We then shift our focus to the periphery using tremor and Tourette's syndrome to illustrate the utility of peripheral biomarkers and interventions. Finally, we discuss current innovations which are changing the landscape of stimulation strategy by integrating technological advances and the use of machine learning to drive optimization