389 research outputs found
Estudio ecologico comparado del problamiento ornitico de dos lagunas navarras de origen endorreico
146 páginas, 15 figuras.Peer reviewe
Physical Education Classes as a Precursor to the Mediterranean Diet and the Practice of Physical Activity
Physical activity and a healthy, balanced diet are remaining unresolved issues among young people. According to the World Health Organization, young people do not get enough exercise during the week, and physical education classes are the best way to promote healthy habits. This study aims to analyze how the role of the teacher influences the frustration of psychological needs, coping strategies, motivation, and the adoption of healthy eating habits through the Mediterranean diet and the regular practice of physical activity. The study involved 1031 boys and 910 girls between the ages of 13 and 18. To explain the relationships between the different variables included in this study, a model of structural equations has been developed. The results showed that autonomy support negatively predicted the frustration of four psychological needs. The failure to meet four psychological needs negatively predicted resilience. Likewise, resilience positively predicted autonomous motivation, and this positively predicted the Mediterranean diet and the practice of physical activity. Thus, the results obtained in the present study are in line with those of various studies wherein physical education classes were seen to help consolidate healthy living habits
A seabird’s eye view: visual fields of some seabirds (Laridae and Procellariidae) from tropical latitudes
The visual field of a bird defines the amount of information that can be extracted from the environment around it, using the eyes. Previous visual field research has left large phylogenetic gaps, where tropical bird species have been comparatively understudied. Using the ophthalmoscopic technique, we measured the visual fields of seven tropical seabird species, to understand what are the primary determinants of their visual fields. The visual field topographies of the seven seabird species were relatively similar, despite the two groups of Terns (Laridae) and Shearwaters (Procellariidae) being phylogenetically distant. We propose this similarity is due to their largely similar foraging ecology. These findings support previous research that foraging ecology rather than relatedness is the key determining factor behind a bird’s visual field topography. Some bird species were identified to have more limited binocular fields, such as Brown Noddies (Anous stolidus) where binocularity onsets lower down within the visual field, resulting in a larger blind area about the head
Targeted co-expression networks for the study of traits
Weighted Gene Co-expression Network Analysis (WGCNA) is a widely used approach for the generation of gene co-expression networks. However, networks generated with this tool usually create large modules with a large set of functional annotations hard to decipher. We have developed TGCN, a new method to create Targeted Gene Co-expression Networks. This method identifies the transcripts that best predict the trait of interest based on gene expression using a refinement of the LASSO regression. Then, it builds the co-expression modules around those transcripts. Algorithm properties were characterized using the expression of 13 brain regions from the Genotype-Tissue Expression project. When comparing our method with WGCNA, TGCN networks lead to more precise modules that have more specific and yet rich biological meaning. Then, we illustrate its applicability by creating an APP-TGCN on The Religious Orders Study and Memory and Aging Project dataset, aiming to identify the molecular pathways specifically associated with APP role in Alzheimer\u27s disease. Main biological findings were further validated in two independent cohorts. In conclusion, we provide a new framework that serves to create targeted networks that are smaller, biologically relevant and useful in high throughput hypothesis driven research. The TGCN R package is available on Github: https://github.com/aliciagp/TGCN
Slamf6 negatively regulates autoimmunity
The nine SLAM family (Slamf) receptors are positive or negative regulators of adaptive and innate immune responses, and of several autoimmune diseases. Here we report that the transfer of Slamf6-/- B6 CD4+ T cells into co-isogenic bm12 mice causes SLE-like autoimmunity with elevated levels of autoantibodies. In addition, significantly higher percentages of Tfh cells and IFN-γ-producing CD4+ cells, as well as GC B cells were observed. Interestingly, the expression of the Slamf6-H1 isoform in Slamf6-/- CD4+ T cells did not induce this lupus-like phenotype. By contrast, Slamf1-/- or Slamf5-/- CD4+ T cells caused the same pathology as WT CD4+ T cells. As the transfer of Slamf [1+6]-/- or Slamf [1+5+6]-/- CD4+ T cells induced WT levels of autoantibodies, the presence of Slamf1 was requisite for the induction of increased levels of autoantibodies by Slamf6-/- CD4+ T cells. We conclude that Slamf6 functions as an inhibitory receptor that controls autoimmune responses
Effectiveness of a program of romana’s Pilates for non-specific low back pain: A pilot study
Objetivo: comprobar la efectividad del método Pilates Romana para conseguir
una mayor flexibilidad de la columna, junto con una mejora en la movilidad de la
misma, así como del dolor que presentan en su vida diaria los pacientes.
Metodología: ensayo clínico con intención de tratar a treinta pacientes con dolor
lumbar inespecífico. Asistieron a 15 sesiones, 2 veces a la semana, del Método
Pilates Romana.. Se evaluaron parámetros tales como dolor, test de Schöber,
SRS-22 y distancia dedos- suelo.
Resultados. Se encontraron diferencias estadísticamente significativas con
respecto al dolor (escala EVA), distancia dedos- suelo, test de Schöber
(flexibilidad en plano sagital), flexión lateral (flexibilidad en plano frontal) y en
varios ítems de la escala SRS-22, con valores de p<0,001. Por ello, este método
puede ser usado para mejorar el dolor, la flexibilidad axial, la función y los
aspectos relacionados con la calidad de vidaAim: to test the effectiveness of the Romana’s Pilates method to obtain
increased flexibility, improvements in mobility, and reduced pain in daily life.
Methodology: a clinical trial with intention-to-treat thirty patients with nonspecific
low back pain. Participants attended 15 sessions, twice a week. The
Romana’s Pilates method was taught by an external physiotherapist.
Parameters such as pain, the Schober test, and the SRS-22 were evaluated.
Results: Statistically significant differences in pain (VAS), the Schober test
(flexibility in sagittal plane), lateral flexion (flexibility in frontal plane) and several
items of the SRS-22 scale were found, with p <0.001.
This method may be used to improve pain, axial flexibility, function and aspects
related to the quality of life of patient
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