Unexpected Features of Supersymmetry with Central Charges

It is shown that N=2 supersymmetric theories with central charges present some hidden quartic symmetry. This enables us to construct representations of the quartic structure induced by superalgebra representations.Comment: 14 pages, more details have been given, to appear in J. Phys.

Pharmacological activation of the nuclear receptor REV-ERB reverses cognitive deficits and reduces amyloid-β burden in a mouse model of Alzheimer’s disease

Alzheimer’s disease currently lacks treatment options that effectively reverse the biological/anatomical pathology and cognitive deficits associated with the disease. Loss of function of the nuclear receptor REV-ERB is associated with reduced cognitive function in mouse models. The effect of enhanced REV-ERB activity on cognitive function has not been examined. In this study, we tested the hypothesis that enhanced REV-ERB function may enhance cognitive function in a model of Alzheimer’s disease. We utilized the REV-ERB agonist SR9009 to pharmacologically activate the activity of REV-ERB in the SAMP8 mouse model of Alzheimer’s disease. SR9009 reversed cognitive dysfunction of an aged SAMP8 mouse in several behavioral assays including novel object recognition, T-maze foot shock avoidance, and lever press operant conditioning task assessments. SR9009 treatment reduced amyloid-β 1–40 and 1–42 levels in the cortex, which is consistent with improved cognitive function. Furthermore, SR9009 treatment led to increased hippocampal PSD-95, cortical synaptophysin expression and the number of synapses suggesting improvement in synaptic function. We conclude that REV-ERB is a potential target for treatment of Alzheimer’s disease.</div

Analisa Aspek Keuangan Pada Perencanaan Klaster Bangunan Rumah Tinggal Dengan Konsep Efisiensi Energi

Saat ini bisnis properti di Indonesia berkembang sangat pesat, khususnya bidang Perumahan. Tetapi pembangunan rumah tinggal yang dilakukan banyak investor kerap kali berorientasi pada keuntungan yang maksimum tanpa memperhatikan dampak terhadap lingkungan dalam jangka panjang. Maka, diperlukan pembangunan klaster Perumahan dengan konsep efisiensi energi. Pembangunan harus disertai dengan analisis keuangan yang matang agar proyek dapat dibangun dan memiliki nilai tambah bagi pengembang. Desain rumah pada klaster ini terlebih dahulu dianalisis dengan 4 aspek yaitu perhitungan Overall Thermal Transfer Value, pencahayaan buatan, sistem pengkondisian udara, dan adanya sumber energi yang terbarukan.Desain rumah kemudian diperhitungkan rencana anggaran biayanya dan disimulasikan dilakukan dengan membuat sebuah cashflow dan dianalisis dengan NPV.Hasil analisa menunjukkan investasi yang dilakukan adalah menguntungkan untuk dilaksanakan jika disimulasikan selama 4 tahun. Keuntungan yang diperoleh pada bulan Januari 2016 adalah sebesar Rp11.278.849.952,99

Ternary algebras and groups

We construct explicitly groups associated to specific ternary algebras which extend the Lie (super)algebras (called Lie algebras of order three). It turns out that the natural variables which appear in this construction are variables which generate the three-exterior algebra. An explicit matrix representation of a group associated to a peculiar Lie algebra of order three is constructed considering matrices with entry which belong to the three exterior algebra.Comment: 11 pages contribution to the 5th International Symposium on Quantum Theory and Symmetries (QTS5

Design of the Spitzer Space Telescope Heritage Archive

It is predicted that Spitzer Space Telescope’s cryogen will run out in April 2009, and the final reprocessing for the cryogenic mission is scheduled to end in April 2011, at which time the Spitzer archive will be transferred to the NASA/IPAC Infrared Science Archive (IRSA) for long-term curation. The Spitzer Science Center (SSC) and IRSA are collaborating to design and deploy the Spitzer Heritage Archive (SHA), which will supersede the current Spitzer archive. It will initially contain the raw and final reprocessed cryogenic science products, and will eventually incorporate the final products from the Warm mission. The SHA will be accompanied by tools deemed necessary to extract the full science content of the archive and by comprehensive documentation

Pitfalls in Quantitative Myocardial PET Perfusion I: Myocardial Partial Volume Correction

BACKGROUND: PET quantitative myocardial perfusion requires correction for partial volume loss due to one-dimensional LV wall thickness smaller than scanner resolution. METHODS: We aimed to assess accuracy of risk stratification for death, MI, or revascularization after PET using partial volume corrections derived from two-dimensional ACR and three-dimensional NEMA phantoms for 3987 diagnostic rest-stress perfusion PETs and 187 MACE events. NEMA, ACR, and Tree phantoms were imaged with Rb-82 or F-18 for size-dependent partial volume loss. Perfusion and Coronary Flow Capacity were recalculated using different ACR- and NEMA-derived partial volume corrections compared by Kolmogorov-Smirnov statistics to standard perfusion metrics with established correlations with MACE. RESULTS: Partial volume corrections based on two-dimensional ACR rods (two equal radii) and three-dimensional NEMA spheres (three equal radii) over estimate partial volume corrections, quantitative perfusion, and Coronary Flow Capacity by 50% to 150% over perfusion metrics with one-dimensional partial volume correction, thereby substantially impairing correct risk stratification. CONCLUSIONS: ACR (2-dimensional) and NEMA (3-dimensional) phantoms overestimate partial volume corrections for 1-dimensional LV wall thickness and myocardial perfusion that are corrected with a simple equation that correlates with MACE for optimal risk stratification applicable to most PET-CT scanners for quantifying myocardial perfusion

Pengembangan Kawasan Pondok Pesantren Al Muayyad Laweyan Sebagai Kawasan Industri Kreatif Berbasis Halal Tourism

Al-Muayyad merupakan pondok pesantren Al-Quran,tertua di kota surakarta yang dirintis tahun 1930 olen K.H. Abdul Mannan bersama K.H. Ahmad Shofawi dan Prof. K.H. Moh Adnan. Pesantren ini berlokasi di kota Surakarta yang merupakan sentra perdagangan batik dan produk tekstil lainnya, pendidikan, budaya Jawa, sekaligus tempat kelahiran tokoh-tokoh dan organisasi-organisasi pergerakan nasional. Secara geografis pesantren berlokasi di daerah perlintasan antar kota di jawa, sehingga tidak menutup kemungkinan bahwa kedepan Kawasan pesantren ini akan ramai di lalui berbagai macam kalangan dari berbagai daerah. Dengan melalui pengamatan secara observatif yang di tujukan untuk Kawasan pondok pesantren Al-Muayyad dan sekitarnya sehingga dapat menghasilkan data yang akan digunakan untuk bahan pertimbangan dalam mengembangkan pemberdayaan Kawasan dan lingkungan hidup. Laweyan sebagai sentra industri yang tidak terlepas dari batik dan budaya lokal merambah ke Kawasan pesantren Al-Muayyad sebagai sebagai roda penggerak perekonomian lokal melalui kegiatan kegiatan inovatif. Sehingga dengan adanya penelitian ini diharapkan dapat membantu berupa memberikan gambaran mengenai potensi yang ada disana yang nantinya akan di kembangkan lanjutkan dalam proses menuju Kawasan industri bertajuk Halal Tourism

Use of Fatty Acid Analysis to Determine Dispersal of Caspian Terns in the Columbia River Basin, U.S.A.

Lethal control, which has been used to reduce local abundances of animals in conflict with humans or with endangered species, may not achieve management goals if animal movement is not considered. In populations with emigration and immigration, lethal control may induce compensatory immigration, if the source of attraction remains unchanged. Within the Columbia River Basin (Washington, U.S.A.), avian predators forage at dams because dams tend to reduce rates of emigration of juvenile salmonids (Oncorhynchus spp.), artificially concentrating these prey. We used differences in fatty acid profiles between Caspian Terns (Hydroprogne caspia) at coastal and inland breeding colonies and terns culled by a lethal control program at a mid-Columbia River dam to infer dispersal patterns. We modeled the rate of loss of fatty acid biomarkers, which are fatty acids that can be traced to a single prey species or groups of species, to infer whether and when terns foraging at dams had emigrated from the coast. Nonmetric multidimensional scaling showed that coastal terns had high levels of C20 and C22 monounsaturated fatty acids, whereas fatty acids of inland breeders were high in C18:3n3, C20:4n6, and C22:5n3. Models of the rate of loss of fatty acid showed that approximately 60% of the terns collected at Rock Island Dam were unlikely to have bred successfully at local (inland) sites, suggesting that terns foraging at dams come from an extensive area. Fatty acid biomarkers may provide accurate information about patterns of dispersal in animal populations and may be extremely valuable in cases where populations differ demonstrably in prey base

REDUCED KINETIC MECHANISM FOR REACTIVE FLOW SIMULATION OF SYNGAS/METHANE COMBUSTION AT GAS TURBINE CONDITIONS

ABSTRACT The reduced kinetic mechanism for syngas/methane developed in the present work consists of a global reaction step for fuel decomposition in which the fuel molecule breaks down into CH 2 O and H 2 . A detailed CH 2 O/H 2 /O 2 elementary reaction sub-set is included as the formation of intermediate combustion radicals such as OH, H, O, HO 2 , and H 2 O 2 is essential for accurate predictions of non-equilibrium phenomena such as ignition and extinction. Since the chemical kinetics of H 2 and CH 2 O are the fundamental building blocks of any hydrocarbon oxidation, the inclusion of detailed kinetic mechanisms for CH 2 O and H 2 oxidation enables the reduced mechanism to predict over a wide range of operating conditions provided the reaction rate parameters of fuel-decomposition reaction is optimized over those conditions. Therefore, the rate coefficients for the fuel-decomposition step are estimated and optimized for the ignition delay time measurements of CH 4 , H 2 , CH 4 /H 2, CH 4 /CO and CO/H 2 mixtures available in the literature over a wide range of pressures, temperatures and equivalence ratios that are relevant to gas turbine operating conditions. The optimized reduced mechanism, consisting of 15 species and around 40 reactions, is able to predict the ignition delay time and laminar flame speed measurements of CH 4 , H 2 , CH 4 /H 2 , CH 4 /CO and CO/H 2 mixtures fairly well over a wide range conditions. The model predictions are also compared with that of GRI3.0 mechanism. The reduced kinetic mechanism predicts the ignition delay time of CH 4 and CH 4 /H 2 mixtures far better than GRI mechanism at higher pressures. To demonstrate the predictive capability of the model in reactive flow systems, the reduced mechanism was implemented in Star-CD/KINetics commercial code using a RANS turbulence model to simulate CH 4 /air premixed combustion in a backward facing step. The CFD model predictions of the stable species in the exhaust gas agree well with the GRI mechanism predictions in a chemical reactor network modeling by approximating the backward facing step with a series of perfectly-stirred reactor and plug-flow reactor. INTRODUCTION The production of syngas and H 2 -enriched fuels from Integrated Gasification Combined Cycles (IGCC) technology has become economically and environmentally feasible due to increased energy cost in recent times. Although the term &apos;syngas&apos; refers to a fuel mixture of CO and H 2 , many of the H 2 -enriched fuels from IGCC consists of mainly CO, H 2 , CH 4 and N 2 and trace amount of COS, H 2 S and NH 3 . Moreover, the composition of H 2 -enriched fuel mixtures varies widely; for example, the methane composition in the fuel mixtures can vary from 6.5 to 65 mole