La neuroarquitectura en los modelos de aprendizaje en la Institución Educativa Inicial CISEA Huarupampa 0909788, Huaraz 2022

El motivo principal de esta investigación científica fue identificar los beneficios de la neuroarquitectura en los modelos de aprendizaje en la I.E.I. CISEA HUARUPAMPA 0909788. La metodología aplicada fue de enfoque cualitativo, diseño fenomenológico, el número de participantes fue de 116 infantes. Los métodos de recolección de datos utilizados fueron las entrevistas, fichas de observación, casos análogos y análisis de normatividad, aplicados a los preescolares; los arquitectos y pedagogos expertos, con la finalidad de realizar una investigación confiable, veraz y actual. Obteniendo como resultado que los colores, iluminación, calor, ruido, frío, vegetación natural, texturas, espacios educativos flexibles, permeables e integrables con el exterior, benefician el desarrollo de los aprendizajes kinestésicos, social y visual del preescolar; un 55% prefiere realizar las actividades académicas en espacios abiertos, así mismo a un 31% no le gusta el color negro y el marrón al 27%. Se concluye que en la I.E.I. CISEA HUARUPAMPA 0909788 no se aplicaron los beneficios neuroarquitectónicos, los colores aplicados en los ambientes y mobiliarios no son los adecuados para los infantes por ello el desempeño del alumno se ve claramente afectado por el entorno, la falta de vegetación repercute negativamente en el preescolar, pues no contribuye con la percepción de este e influye con la instrucción al mundo real, así mismo afectan en el desenvolvimiento creativo y emocional del preescolar

Diseño de un sistema de tratamiento biológico para las aguas residuales de la cabecera parroquial de Sevilla don Bosco-cantón Morona-provincia de Morona Santiago.

Se diseñó un Sistema de Tratamiento Biológico de Aguas Residuales para la Cabecera Parroquial de Sevilla Don Bosco con el objetivo de mitigar los impactos ambientales por la descarga a un cuerpo de agua dulce y el cumplimiento con la Normativa Ambiental Ecuatoriana. La investigación inició con la identificación del estado actual de la descarga del agua residual para realizar una caracterización inicial aplicando un tipo de muestreo compuesto, el cual permitió conocer los parámetros que se encuentran fuera de los límites permisibles de las normas del Texto Unificado de Legislación Ambiental (TULSMA), los mismos que se detallan a continuación: Aceites y Grasas 52,13 mg/L, Demanda Bioquímica de Oxígeno (DBO) 131,33 mg/L, Demanda Química de Oxígeno (DQO) 264 mg/L, Sólidos Suspendidos 158,33 mg/L, Sólidos Sedimentables 13,67 mg/L, Coliformes Fecales 88000 UFC/100 ml, posteriormente se procedió a determinar el caudal que se efectuó por siete días consecutivos, aplicando el método volumétrico en intervalos de 3 horas desde las 07h00 hasta las 19h00, obteniendo un caudal de aforo de 2,98 l/s. A partir de los resultados de la caracterización inicial, definido el índice de biodegradabilidad y la simulación de los procesos se procedió a dimensionar los equipos respectivos para el sistema de tratamiento biológico, teniéndose: un canal de recepción, sistema de rejillas, Trampa de Grasas, Humedal Artificial utilizando Lechuguines (Eichhornia Crassipes) y Filtro dual con medios múltiples. El presente diseño fue validado con la caracterización del agua residual obtenida después de la simulación de proceso (planta piloto), alcanzando porcentajes de remoción de: DQO 71,59%, DBO 59,64%, Aceites y Grasas 80,82%, Sólidos Sedimentables 94,15%, Sólidos Suspendidos 91,79 %, Coliformes Fecales 99,32%. Se recomienda al Gobierno Autónomo Descentralizado Parroquial Sevilla Don Bosco implementar el presente estudio realizado para reducir el impacto ambiental generado hacia el Río Upano y sus alrededores.A Biological Wastewater Treatment System was designed for the head parish of Sevilla Don Bosco with the main purpose of mitigating the environmental impacts due to the frequent discharge into a freshwater body and in compliance with the Ecuadorian Environmental Regulations.The investigation began with the identification of the current state of the wastewater discharge to perform an initial characterization by applying a type of composite sampling which allowed to know the parameters that are outside the permissible limits of the Unified Text of Environmental Legislation standards (UTELS), the same as detailed below: Oils and Fats 52,13 mg/L, Biochemical Oxygen Demand (BOD) 131,33 mg/L, Chemical Oxygen Demand (COD) 264 mg/L, Suspended Solids 158,33 mg/L, Sedimentary Solids 13,67 mg/L, Fecal Coliforms 88000 CFU/100 ml, the flow rate was then determined for seven days in a row, applying the volumetric method at intervals of 3 hours from 07h00 until 19h00, obtaining a flow capacity of 2,98 L/s. From the results of the initial characterization, defined by the biodegradability index and the simulation of the processes, the respective equipment for the biological treatment system was sized, taking into account: a reception channel, grid system, grease trap, artificial wetland using lettuce (Eichorna Crassipes) and dual filter with multiple media. The current design was validated with the residual water characterization obtained after the process simulation (pilot plant), reaching removal percentages of: COD 71,59%, BOD 59,64%, Oils and Fats 80,82%, Sedimentary Solids 94,15%, Suspended Solids 91,79%, Fecal Coliforms 99,32%. It is strongly recommended in Sevilla Don Bosco Parish Decentralized Autonomous Government to implement this study to reduce the environmental impact generated towards the Upano River and its surroundings

Evaluación de la calidad fisicoquímica y microbiológica de la leche cruda almacenada en centros de acopio de la provincia de Chimborazo

El objetivo de la presente investigación fue evaluar la calidad fisicoquímica y microbiológica de la leche cruda almacenada en tres centros de acopio (CA) ubicados en el Cantón Guano, provincia de Chimborazo. Se utilizó una lista de chequeo de las condiciones higiénicas sanitarias emitida por Agrocalidad aplicada a los centros de acopio, al transporte que entrega la leche y al que lleva el producto a la Industria Láctea. Se tomaron muestras de leche por duplicado del tanque de almacenamiento en cada CA durante tres días para realizar los análisis fisicoquímicos mediante el equipo LACTOSCAN y pruebas rápidas. Se realizó el recuento de microorganismos indicadores de la calidad sanitaria: Enterobacterias, Staphylococcus aureus, aerobios mesófilos, mohos y levaduras, y el recuento de bacterias ácido-lácticas utilizando las normas técnicas ecuatorianas pertinentes. Se identificó el género y especie de bacterias aisladas de cultivos de Enterobacterias a través tinción Gram y pruebas bioquímicas. Los resultados muestran que la calidad de la leche se ve afectada por la falta de infraestructura e higiene en los CA, y por el bajo nivel de cumplimiento del transporte que entrega la leche al centro. Los resultados en cuanto al análisis fisicoquímico mostraron que pH y punto crioscópico se encontraban fuera de los límites permisibles. Los resultados del recuento de Enterobacterias, aeróbios mesófilos, mohos y levaduras y Staphylococcus aureus, superaron los valores en log10UFC/g 5,11; 6,18; 4,48; 3 a 4, respectivamente. El género y especie de Enterobacterias identificadas fueron Escherichia coli inactivo y Klebsiella pneumoniae. En conclusión, la leche cruda presenta baja calidad microbiológica atribuyéndose a inadecuadas condiciones de manipulación. Se recomienda más investigación del estado de salud de los animales, especialmente lo relacionado a la mastitis y la importancia del efecto de los contenedores para determinar su contribución a la calidad microbiana.The objective of this research work was to evaluate the physicochemical and microbiological quality of raw milk stored in three collection centers (CC) located in Guano Canton, province of Chimborazo. A checklist of the sanitary hygienic conditions issued by Agrocalidad applied to the collection centers, the transport that delivers the milk and the one that takes the product to the Dairy Industry was used. Duplicate milk samples were taken from the storage tank in each CC for three days to perform the physicochemical analyzes using the LACTOSCAN equipment and rapid tests. The count of health quality indicator microorganisms was carried out: Enterobacteria, Staphylococcus aureus, mesophilic aerobes, molds and yeasts, and the lactic acid bacteria count using the relevant Ecuadorian technical standards. The genus and species of bacteria isolated from Enterobacteria cultures were identified through Gram staining and biochemical tests. The results show that milk quality is affected by the lack of infrastructure and hygiene in the CAs, and by the low level of compliance with the transport delivered by the milk to the center. The results regarding the physicochemical analysis showed that pH and cryoscopic point were outside the permissible limits. The results of the count of Enterobacterias, mesophilic aerobes, mold and yeast and Staphylococcus aureus, exceeded the values in log 10UF/g 5.11; 6.18, 4.48; 3 to 4, respectively. The genus and species identified Enterobacteria were inactive Escherichia coli and Klehsiella pneumomae. In conclusion, raw milk has low microbiological quality, attributed to inadequate handling conditions. More research on the health status of animals is recommended, especially related to mastitis and the importance of the effect of containers to determine their contribution to microbial quality

Signaling by AWC Olfactory Neurons Is Necessary for Caenorhabditis elegans' Response to Prenol, an Odor Associated with Nematode-Infected Insects

Chemosensation plays a role in the behaviors and life cycles of numerous organisms, including nematodes. Many guilds of nematodes exist, ranging from the free-living Caenorhabditis elegans to various parasitic species such as entomopathogenic nematodes (EPNs), which are parasites of insects. Despite ecological differences, previous research has shown that both EPNs and C. elegans respond to prenol (3-methyl-2-buten-1-ol), an odor associated with EPN infections. However, it is unclear how C. elegans responds to prenol. By utilizing natural variation and genetic neuron ablation to investigate the response of C. elegans to prenol, we found that the AWC neurons are involved in the detection of prenol and that several genes (including dcap-1, dcap-2, and clec-39) influence response to this odorant. Furthermore, we identified that the response to prenol is mediated by the canonically proposed pathway required for other AWC-sensed attractants. However, upon testing genetically diverse isolates, we found that the response of some strains to prenol differed from their response to isoamyl alcohol, suggesting that the pathways mediating response to these two odorants may be genetically distinct. Further, evaluations leveraging natural variation and genome wide association revealed specific genes that influence nematode behavior and provide a foundation for future studies to better understand the role of prenol in nematode behavioral ecology

Determinants of Depressive Symptoms at 1 Year Following ICU Discharge in Survivors of $ 7 Days of Mechanical Ventilation : Results From the RECOVER Program, a Secondary Analysis of a Prospective Multicenter Cohort Study

Abstract : Background: Moderate to severe depressive symptoms occur in up to one-third of patients at 1 year following ICU discharge, negatively affecting patient outcomes. This study evaluated patient and caregiver factors associated with the development of these symptoms. Methods: This study used the Rehabilitation and Recovery in Patients after Critical Illness and Their Family Caregivers (RECOVER) Program (Phase 1) cohort of 391 patients from 10 medical/surgical university-affiliated ICUs across Canada. We determined the association between patient depressive symptoms (captured by using the Beck Depression Inventory II [BDI-II]), patient characteristics (age, sex, socioeconomic status, Charlson score, and ICU length of stay [LOS]), functional independence measure (FIM) motor subscale score, and caregiver characteristics (Caregiver Assistance Scale and Center for Epidemiologic Studies-Depression Scale) by using linear mixed models at time points 3, 6, and 12 months. Results: BDI-II data were available for 246 patients. Median age at ICU admission was 56 years (interquartile range, 45-65 years), 143 (58%) were male, and median ICU LOS was 19 days (interquartile range, 13-32 days). During the 12-month follow-up, 67 of 246 (27.2%) patients had a BDI-II score ≥ 20, indicating moderate to severe depressive symptoms. Mixed models showed worse depressive symptoms in patients with lower FIM motor subscale scores (1.1 BDI-II points per 10 FIM points), lower income status (by 3.7 BDI-II points; P = .007), and incomplete secondary education (by 3.8 BDI-II points; P = .009); a curvilinear relation with age (P = .001) was also reported, with highest BDI-II at ages 45 to 50 years. No associations were found between patient BDI-II and comorbidities (P = .92), sex (P = .25), ICU LOS (P = .51), or caregiver variables (Caregiver Assistance Scale [P = .28] and Center for Epidemiologic Studies Depression Scale [P = .74]). Conclusions: Increased functional dependence, lower income, and lower education are associated with increased severity of post-ICU depressive symptoms, whereas age has a curvilinear relation with symptom severity. Knowledge of risk factors may inform surveillance and targeted mental health follow-up. Early mobilization and rehabilitation aiming to improve function may serve to modify mood disorders

TIC Y SISTEMAS INTELIGENTES como herramientas de soporte para el manejo, educación y prevención del trauma

La corporación ecuatoriana para el desarrollo de la investigación y la academia,. CEDIA, promueve la exploración y resultados de proyectos innovadores que vinculan a instituciones ecuatorianas. A inicios del año 2014, CEDIA conformó grupos de trabajo en varias áreas d einterés; una de ellas fue Telemedicina y Telesalud debido al gran impacto que tiene dentro de la investigación. Este grupo cuenta con la participación de seis universidades ecuatorianas: Universidad de Cuenca, Universidad Salesiana, Universidad Católica de Cuenca, Universidad del Azuay, Universidad Regional Autónoma de los Andes y Universidad Nacional de Chimborazo. El objetivo de este grupo de trabajo es fortalecer, impulsar y motivar actividades de investigación entre las instituciones miembros de CEDIA en bienestar d ela comunidad. En este libro se visualiza el trabajo realizado por el Grupo de Trabajo en temas de trauma utilizando múltiples formas de tecnología, desde aplicaciones móviles, e-learning, objetos de aprendizaje, hasta sistemas de recolección automatizada de datos; desarrollando programas que impactan en la atención de la salud en el área pre-hospitalaria, prevención de lesiones, registro de trauma, modalidades de educación y aprendizaje, mediante el uso de las TIC

Impact of COVID-19 on cardiovascular testing in the United States versus the rest of the world

Objectives: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-US institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic. Background: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality. Methods: Data were submitted to the INCAPS-COVID (International Atomic Energy Agency Non-Invasive Cardiology Protocols Study of COVID-19), a multinational registry comprising 909 institutions in 108 countries (including 155 facilities in 40 U.S. states), assessing the impact of the COVID-19 pandemic on volumes of diagnostic cardiovascular procedures. Data were obtained for April 2020 and compared with volumes of baseline procedures from March 2019. We compared laboratory characteristics, practices, and procedure volumes between U.S. and non-U.S. facilities and between U.S. geographic regions and identified factors associated with volume reduction in the United States. Results: Reductions in the volumes of procedures in the United States were similar to those in non-U.S. facilities (68% vs. 63%, respectively; p = 0.237), although U.S. facilities reported greater reductions in invasive coronary angiography (69% vs. 53%, respectively; p < 0.001). Significantly more U.S. facilities reported increased use of telehealth and patient screening measures than non-U.S. facilities, such as temperature checks, symptom screenings, and COVID-19 testing. Reductions in volumes of procedures differed between U.S. regions, with larger declines observed in the Northeast (76%) and Midwest (74%) than in the South (62%) and West (44%). Prevalence of COVID-19, staff redeployments, outpatient centers, and urban centers were associated with greater reductions in volume in U.S. facilities in a multivariable analysis. Conclusions: We observed marked reductions in U.S. cardiovascular testing in the early phase of the pandemic and significant variability between U.S. regions. The association between reductions of volumes and COVID-19 prevalence in the United States highlighted the need for proactive efforts to maintain access to cardiovascular testing in areas most affected by outbreaks of COVID-19 infection