A Large Eddy Simulation of Turbulent Compressible Convection: Differential Rotation in the Solar Convection Zone

We present results of two simulations of the convection zone, obtained by solving the full hydrodynamic equations in a section of a spherical shell. The first simulation has cylindrical rotation contours (parallel to the rotation axis) and a strong meridional circulation, which traverses the entire depth. The second simulation has isorotation contours about mid-way between cylinders and cones, and a weak meridional circulation, concentrated in the uppermost part of the shell. We show that the solar differential rotation is directly related to a latitudinal entropy gradient, which pervades into the deep layers of the convection zone. We also offer an explanation of the angular velocity shear found at low latitudes near the top. A non-zero correlation between radial and zonal velocity fluctuations produces a significant Reynolds stress in that region. This constitutes a net transport of angular momentum inwards, which causes a slight modification of the overall structure of the differential rotation near the top. In essence, the {\it thermodynamics controls the dynamics through the Taylor-Proudman momentum balance}. The Reynolds stresses only become significant in the surface layers, where they generate a weak meridional circulation and an angular velocity `bump'.Comment: 11 pages, 14 figures, the first figure was too large and is excluded. Accepted for publication in MNRA

An anatomy of change : profiling cohort difference in beliefs and attitudes among Anglicans in England

Conservatism in theological belief, moral values and attitude toward ecclesiastical practices was measured in a sample of 5967 ordained and lay Anglicans in the Church of England. Average scores were compared between those who classed themselves as Anglo-catholic, broad church or evangelical, and by six different age cohorts. Overall, most measures of conservatism showed decline among more recent cohorts, but there were marked differences between traditions. Younger evangelicals showed little or no decline in theological or moral conservatism, and, in the case of Bible beliefs, were more conservative than their older counterparts. In ecclesiastical variables, however, Anglo-catholics were often more conservative and younger evangelicals showed less conservatism than other traditions or older evangelicals. The findings suggest that the divide between traditions is increasing among younger generations mainly because those in Anglo-catholic and broad-church traditions are becoming more liberal on theological or moral matters, whereas evangelicals are maintaining traditional conservative views of theology and morality but becoming less traditional in matters ecclesiastical

Effects of Annealing Ambient on the Structural, Optical and Electrical Properties of TiO2:Ge Thin Films

TiO2, a semiconducting material with a wide energy band gap, has been researched intensively due to its interesting properties and many potential applications. The films properties can as well be modified by preparing the films under diverse ambient to suit diverse applications. In this work, the effects of the annealing atmosphere on the structural, optical and electrical properties of pure TiO2 and TiO2:Ge composite thin films deposited by sputtering from commercially available pure TiO2 and TiO2:Ge (85:15) targets respectively were studied. The films were deposited on fluorine doped tin oxide glass substrates by radio frequency magnetron sputtering technique at room temperature 23–25 ℃ and then annealed at 450 ℃ for one hour in three different atmospheres: air, argon and nitrogen. The XRD results revealed that, both pure TiO2 and TiO2:Ge thin films were crystalline and had a mixed phase of anatase and rutile regardless of the annealing ambient. The calculated crystallite sizes ranged between 19–21 nm with the particle sizes for TiO2:Ge films being larger compared to pure TiO2 as calculated from ImageJ software. Electrical measurements showed that the resistivity of as deposited pure TiO2 films (about 13.03 × 10–2 Ω-cm) was greater than the TiO2: Ge composite (5.91 × 10–2 Ω-cm). Furthermore, on annealing, pure TiO2 had a resistivity of 9.47 × 10–2 Ω-cm–10.4 × 10–2 Ω-cm, while the TiO2:Ge composite had a resistivity of 2.24 × 10–2 Ω-cm–3.61 × 10–2 Ω-cm depending on the annealing atmosphere. Variation of annealing atmosphere had minimal influence on the electrical resistivity of the films. The films annealed in nitrogen recorded the least resistivity values averaging about 5.86 × 10–2 Ω-cm, while those annealed in argon and air recorded a resistivity of 6.94 × 10–2 Ω-cm and 6.65 × 10–2 Ω-cm, respectively. The transmittance spectra showed that, all the annealed films were transparent in the visible region (400–700 nm) with a mean bandgap of 3.60 eV for each annealing atmosphere. It is recommended that films annealed in nitrogen atmosphere could be considered for potential applications in photovoltaics. Keywords: Titanium dioxide; Germanium; Ambient; Structural; Optical, Electrica

The Baldwin Effect and Black Hole Accretion: A Spectral Principal Component Analysis of a Complete QSO Sample

A unique set of UV-optical spectrograms of 22 low redshift QSOs are investigated using principal component analysis. We find three significant principal components over the broad wavelength range from Ly\alpha to H\alpha. They together account for about 78% of the sample intrinsic variance. We present strong arguments that the first principal component represents the Baldwin effect, relating equivalent widths to the luminosity (i.e. accretion rate), but only emission-line cores are involved. The second component represents continuum variations, probably dominated by intrinsic reddening. The third principal component directly relates QSO UV properties to the optical principal component 1 found by Boroson & Green (1992). It is the primary cause of scatter in the Baldwin relationships. It is also directly related to broad emission-line width and soft X-ray spectral index, and therefore probably driven by Eddington accretion ratio. We demonstrate how Baldwin relationships can be derived using our first principal component, virtually eliminating the scatter caused by the third principal component. This rekindles the hope that the Baldwin relationships can be used for cosmological study.Comment: 35 pages, 13 figures, AASTEX, accepted for publication in Ap

New first trimester crown-rump length's equations optimized by structured data collection from a French general population

--- Objectives --- Prior to foetal karyotyping, the likelihood of Down's syndrome is often determined combining maternal age, serum free beta-HCG, PAPP-A levels and embryonic measurements of crown-rump length and nuchal translucency for gestational ages between 11 and 13 weeks. It appeared important to get a precise knowledge of these scan parameters' normal values during the first trimester. This paper focused on crown-rump length. --- METHODS --- 402 pregnancies from in-vitro fertilization allowing a precise estimation of foetal ages (FA) were used to determine the best model that describes crown-rump length (CRL) as a function of FA. Scan measures by a single operator from 3846 spontaneous pregnancies representative of the general population from Northern France were used to build a mathematical model linking FA and CRL in a context as close as possible to normal scan screening used in Down's syndrome likelihood determination. We modeled both CRL as a function of FA and FA as a function of CRL. For this, we used a clear methodology and performed regressions with heteroskedastic corrections and robust regressions. The results were compared by cross-validation to retain the equations with the best predictive power. We also studied the errors between observed and predicted values. --- Results --- Data from 513 spontaneous pregnancies allowed to model CRL as a function of age of foetal age. The best model was a polynomial of degree 2. Datation with our equation that models spontaneous pregnancies from a general population was in quite agreement with objective datations obtained from 402 IVF pregnancies and thus support the validity of our model. The most precise measure of CRL was when the SD was minimal (1.83mm), for a CRL of 23.6 mm where our model predicted a 49.4 days of foetal age. Our study allowed to model the SD from 30 to 90 days of foetal age and offers the opportunity of using Zscores in the future to detect growth abnormalities. --- Conclusion --- With powerful statistical tools we report a good modeling of the first trimester embryonic growth in the general population allowing a better knowledge of the date of fertilization useful in the ultrasound screening of Down's syndrome. The optimal period to measure CRL and predict foetal age was 49.4 days (9 weeks of gestational age). Our results open the way to the detection of foetal growth abnormalities using CRL Zscores throughout the first trimester

ImpZ: a new photometric redshift code for galaxies and quasars

We present a combined galaxy-quasar approach to template-fitting photometric redshift techniques and show the method to be a powerful one. The code (ImpZ) is presented, developed and applied to two spectroscopic redshift catalogues, namely the Isaac Newton Telescope Wide Angle Survey ELAIS N1 and N2 fields and the Chandra Deep Field North. In particular, optical size information is used to improve the redshift determination. The success of the code is shown to be very good with Delta z/(1+z) constrained to within 0.1 for 92 per cent of the galaxies in our sample. The extension of template-fitting to quasars is found to be reasonable with Delta z/(1+z) constrained to within 0.25 for 68 per cent of the quasars in our sample. Various template extensions into the far-UV are also tested.Comment: 21 pages. MNRAS in press. Minor alterations to match MNRAS final proo

Overexpression of Map3k7 activates sinoatrial node-like differentiation in mouse ES-derived cardiomyocytes

In vivo, cardiomyocytes comprise a heterogeneous population of contractile cells defined by unique electrophysiologies, molecular markers and morphologies. The mechanisms directing myocardial cells to specific sub-lineages remain poorly understood. Here we report that overexpression of TGFβ-Activated Kinase (TAK1/Map3k7) in mouse embryonic stem (ES) cells faithfully directs myocardial differentiation of embryoid body (EB)-derived cardiac cells toward the sinoatrial node (SAN) lineage. Most cardiac cells in Map3k7-overexpressing EBs adopt markers, cellular morphologies, and electrophysiological behaviors characteristic of the SAN. These data, in addition to the fact that Map3k7 is upregulated in the sinus venous—the source of cells for the SAN—suggest that Map3k7 may be an endogenous regulator of the SAN fate

Long-term voluntary wheel running does not alter vascular amyloid burden but reduces neuroinflammation in the Tg-SwDI mouse model of cerebral amyloid angiopathy

Background: Cardiovascular exercise (CVE) has been shown to be protective against cognitive decline in aging and the risk for dementias, including Alzheimer’s Disease (AD). CVE has also been shown to have several beneficial effects on brain pathology and behavioral impairments in mouse models of AD; however, no studies have specifically examined the effects of CVE on cerebral amyloid angiopathy (CAA), which is the accumulation of amyloid-beta (Aβ) in the cerebral vasculature. CAA may be uniquely susceptible to beneficial effects of CVE interventions due to the location and nature of the pathology. Alternatively, CVE may exacerbate CAA pathology, due to added stress on already compromised cerebral vasculature. Methods: In the current study, we examined the effects of CVE over many months in mice, thereby modeling a lifelong commitment to CVE in humans. We assessed this voluntary CVE in Tg-SwDI mice, a transgenic mouse model of CAA that exhibits behavioral deficits, fibrillar vascular Aβ pathology, and significant perivascular neuroinflammation. Various “doses” of exercise intervention (0 h (“Sedentary”), 1 h, 3 h, 12 h access to running wheel) were assessed from ~ 4 to 12 months of age for effects on physiology, behavior/cognitive performance, and pathology. Results: The 12 h group performed the greatest volume of exercise, whereas the 1 h and 3 h groups showed high levels of exercise intensity, as defined by more frequent and longer duration running bouts. Tg-SwDI mice exhibited significant cerebral vascular Aβ pathology and increased expression of pro-inflammatory cytokines as compared to WT controls. Tg-SwDI mice did not show motor dysfunction or altered levels of anxiety or sociability compared to WT controls, though Tg-SwDI animals did appear to exhibit a reduced tendency to explore novel environments. At all running levels, CAA pathology in Tg-SwDI mice was not significantly altered, but 12-h high-volume exercise showed increased insoluble Aβ burden. However, CVE attenuated the expression of pro-inflammatory cytokines TNF-α and IL-6 and was generally effective at enhancing motor function and reducing anxiety-like behavior in Tg-SwDI mice, though alterations in learning and memory tasks were varied. Conclusions: Taken together, these results suggest that CAA can still develop regardless of a lifespan of substantial CVE, although downstream effects on neuroinflammation may be reduced and functional outcomes improved