Interpretation of the northern boundary of Ishtar Terra from Magellan images and altimetry

Part of the controversy on the origin of western Ishtar Terra (IT) concerns the nature of Uorsar Rupes (UR), the northern boundary of IT. In the hypothesis of lithospheric convergence and underthrusting, UR is held to be the main boundary thrust fault at the toe of an accretionary wedge. A topographic rise parallel to the scarp was interpreted as a flexural bulge similar to those of terrestrial subduction zones, and quantitative models of this feature seemed broadly consistent with the expected lithospheric structure of Venus. In the alternative mantle upwelling hypothesis for western IT, the outer margins of the highland are thought to be collapsing, and UR has been interpreted as a normal fault. Herein, Magellan images and altimetry are interpreted for this region and the hypothesis that a flexural signature can be distinguished is reassessed. The Magellan images of IT show evidence of crustal shortening adjacent to UR, but extension and burial dominate northwards. Altimetric profiles display the same long wavelength trends visible in Venera data, but no clear evidence of the lithospheric flexure. A model of regional extension and burial is herein favored, but regional compression cannot be ruled out

CURRENT RESEARCH ON IMPROVING CAPTURE DEVICES FOR COYOTES

Nine types of footsnares were tested on captive coyotes (Canis latrans) at the United States Department of Agriculture Predator Research Facility. Preliminary results indicate that the E-Z Lee, Nelson, Freemont, and Godwin leg snares can be effective in restraining coyotes while causing only minor leg injuries. Additional testing will be required to determine the effectiveness of these devices in different field situations. Four types of coyote leg-hold traps were evaluated to determine the injuries they inflict on captured coyotes. The No. 3 1/2 McBride padded trap caused the least injury in comparison to 3 other trap models that were tested. Available data on injuries associated with different traps will assist in determining what types of capture devices meet standards set by the International Organization for Standardization. The potential implementation of International Trap Standards will most likely determine the future use of traps and snares in much of the world. Wildlife managers should continue to search for improvements if they desire to maintain the use of traps in the future

Leg Injuries To Coyotes Captured In Standard And Modified Soft Catch® Traps

Leg injuries of coyotes (Canis latrans) captured in standard No. 3 Soft Catch traps were compared with those captured in the same trap type modified with two additional coil springs. One hundred thirteen coyotes were trapped in southern California in conjunction with livestock predator control operations, 53 in standard traps, and 60 in modified traps. Observed injuries were similar in both trap types. The most frequent injuries were edematous hemorrhages and small cutaneous lacerations. Injuries, such as joint luxations and bone fractures, were noted more frequently for coyotes trapped in standard Soft Catch traps

Anesthetic Activity of Acetylated MS-222 in Tilapia (Oreochromis Niloticus)

A group of 8 tilapia (Oreochromis niloticus) were anesthetized once per week for six consecutive weeks, using tricaine methanesulfonate (MS-222) in the water. Time for the fish to reach anesthesia decreased significantly over the first four weeks, and then plateaued at about 27% below the first anesthetic exposure. These results suggest induction of the liver enzymes that convert MS-222 into metabolites, one or more of which have higher anesthetic activity than the parent compound. Major metabolites of MS-222 have been identified as part of regulatory studies evaluating residue persistence in food fishes. One of these metabolites, N-acetyl-3-aminobenzoic acid ethyl ester, which is acetylated MS-222, was selected for testing of anesthetic activity in tilapia. This report shows results of the testing, and speculates as to the potential utility of the acetylated metabolite of MS-222 as an alternate anesthetic agent in fish

Managing for Stakeholders, Stakeholder Utility Functions, and Competitive Advantage

This paper integrates some of the central concepts of stakeholder theory with the literatures on organizational justice and trust to explain firm competitiveness. It provides a detailed explanation of factors that facilitate acquisition of knowledge about stakeholder utility functions. In addition, it offers a knowledge-based analysis of how firms that manage for stakeholders can enjoy sustainable competitive benefits. These explanations provide a strong rationale for including stakeholder theory in the discussion of firm competitiveness and performance

Survival rates and prognostic predictors of high grade brain stem gliomas in childhood : a systematic review and meta-analysis

Diagnosis of a pediatric high grade brain stem glioma is devastating with dismal outcomes. This systematic review and meta-analysis was undertaken to determine the survival rates and assess potential prognostic factors including selected interventions. Studies included involved pediatric participants with high grade brain stem gliomas diagnosed by magnetic resonance imaging or biopsy reporting overall survival rates. Meta-analysis was undertaken using a binomial random effects model. Sixty-five studies (2336 participants) were included. Meta-analysis showed 1 year overall survival (OS) of 41% (95% confidence interval (CI) 38-44%, I-sq 52%, 2083 participants), 2 year OS of 15.3% (95% confidence interval 12-20%, I-sq 73.1%, 1329 participants) and 3 year OS of 7.3% (95% confidence interval 5.2-10%, I-sq 26%, 584 participants). Meta-analyses of median overall survival results was not possible due to the lack of reported measures of variance. Subgroup analysis comparing date of study, classification of tumor, use of temozolomide, non-standard interventions or phase 1/2 versus other studies demonstrated no difference in survival outcomes. There was insufficient data to undertake subgroup meta-analysis of patient age, duration of symptoms, K27M histone mutations and AVCR1 mutations. Survival outcomes of high grade brain stem gliomas have remained very poor, and do not clearly vary according to classification, phase of study or use of different therapeutic interventions. Future studies should harmonize outcome and prognostic variable reporting to enable accurate meta-analysis and better exploration of prognosis

Development of status epilepticus, sustained calcium elevations and neuronal injury in a rat survival model of lethal paraoxon intoxication

Paraoxon (POX) is an active metabolite of organophosphate (OP) pesticide parathion that has been weaponized and used against civilian populations. Exposure to POX produces high mortality. OP poisoning is often associated with chronic neurological disorders. In this study, we optimize a rat survival model of lethal POX exposures in order to mimic both acute and long-term effects of POX intoxication. Male Sprague–Dawley rats injected with POX (4 mg/kg, ice-cold PBS, s.c.) produced a rapid cholinergic crisis that evolved into status epilepticus (SE) and death within 6–8 min. The EEG profile for POX induced SE was characterized and showed clinical and electrographic seizures with 7–10 Hz spike activity. Treatment of 100% lethal POX intoxication with an optimized three drug regimen (atropine, 2 mg/kg, i.p., 2-PAM, 25 mg/kg, i.m. and diazepam, 5 mg/kg, i.p.) promptly stopped SE and reduced acute mortality to 12% and chronic mortality to 18%. This model is ideally suited to test effective countermeasures against lethal POX exposure. Animals that survived the POX SE manifested prolonged elevations in hippocampal [Ca2+]i(Ca2+ plateau) and significant multifocal neuronal injury. POX SE induced Ca2+ plateau had its origin in Ca2+ release from intracellular Ca2+ stores since inhibition of ryanodine/IP3 receptor lowered elevated Ca2+ levels post SE. POX SE induced neuronal injury and alterations in Ca2+ dynamics may underlie some of the long term morbidity associated with OP toxicity

Post-drought decline of the Amazon carbon sink

Amazon forests have experienced frequent and severe droughts in the past two decades. However, little is known about the large-scale legacy of droughts on carbon stocks and dynamics of forests. Using systematic sampling of forest structure measured by LiDAR waveforms from 2003 to 2008, here we show a significant loss of carbon over the entire Amazon basin at a rate of 0.3 ± 0.2 (95% CI) PgC yr−1 after the 2005 mega-drought, which continued persistently over the next 3 years (2005–2008). The changes in forest structure, captured by average LiDAR forest height and converted to above ground biomass carbon density, show an average loss of 2.35 ± 1.80 MgC ha−1 a year after (2006) in the epicenter of the drought. With more frequent droughts expected in future, forests of Amazon may lose their role as a robust sink of carbon, leading to a significant positive climate feedback and exacerbating warming trends.The research was partially supported by NASA Terrestrial Ecology grant at the Jet Propulsion Laboratory, California Institute of Technology and partial funding to the UCLA Institute of Environment and Sustainability from previous National Aeronautics and Space Administration and National Science Foundation grants. The authors thank NSIDC, BYU, USGS, and NASA Land Processes Distributed Active Archive Center (LP DAAC) for making their data available. (NASA Terrestrial Ecology grant at the Jet Propulsion Laboratory, California Institute of Technology)Published versio

Lunar and Martian hardware commonality

A number of different hardware elements were examined for possible Moon/Mars program commonality. These include manned landers; cargo landers, a trans-Mars injection (TMI) stage, traverse vehicles, unmanned surface rovers, habitation modules, and power supplies. Preliminary analysis indicates that it is possible to build a common two-stage manned lander. A single-stage, reusable lander may be practical for the lunar cast, but much less so for the Martian case, and commonality may therefore exist only at the subsystem level. A modified orbit transfer vehicle was examined as a potential cargo lander. Potential cargoes to various destinations were calculated for a Shuttle external tank sized TMI stage. A nuclear powered, long range traverse vehicle was conceptually designed and commonality is considered feasible. Short range, unmanned rovers can be made common without great effort. A surface habitation module may be difficult to make common due to difficulties in landing certain shapes on the Martian surface with aerobraking landers. Common nuclear power sources appear feasible. High temperature radiators appear easy to make common. Low temperature radiators may be difficult to make common. In most of these cases, Martian requirements determine the design