An early peak in the radio light curve of short-duration Gamma-Ray Burst 200826A

We present the results of radio observations from the eMERLIN telescope combined with X-ray data from Swift for the short-duration Gamma-ray burst (GRB) 200826A, located at a redshift of 0.71. The radio light curve shows evidence of a sharp rise, a peak around 4-5 days post-burst, followed by a relatively steep decline. We provide two possible interpretations based on the time at which the light curve reached its peak. (1) If the light curve peaks earlier, the peak is produced by the synchrotron self-absorption frequency moving through the radio band, resulting from the forward shock propagating into a wind medium and (2) if the light curve peaks later, the turn over in the light curve is caused by a jet break. In the former case, we find a minimum equipartition energy of ~3x10^47 erg and bulk Lorentz factor of ~5, while in the latter case we estimate the jet opening angle of ~9-16 degrees. Due to the lack of data, it is impossible to determine which is the correct interpretation, however, due to its relative simplicity and consistency with other multi-wavelength observations which hint at the possibility that GRB 200826A is in fact a long GRB, we prefer scenario one over scenario two.Comment: 7 pages, 3 figures, accepted to MNRA

Fatigue in fibromyalgia: a conceptual model informed by patient interviews

Abstract Background Fatigue is increasingly recognized as an important symptom in fibromyalgia (FM). Unknown however is how fatigue is experienced by individuals in the context of FM. We conducted qualitative research in order to better understand aspects of fatigue that might be unique to FM as well as the impact it has on patients' lives. The data obtained informed the development of a conceptual model of fatigue in FM. Methods Open-ended interviews were conducted with 40 individuals with FM (US [n = 20], Germany [n = 10] and France [n = 10]). Transcripts were analyzed using qualitative methods based upon grounded theory to identify key themes and concepts. Results Participants were mostly female (70%) with a mean age of 48.7 years (range: 25-79). Thirty-one individuals (i.e., 77.5%) spontaneously described experiencing tiredness/lack of energy/fatigue due to FM. Participants discussed FM fatigue as being more severe, constant/persistent and unpredictable than normal tiredness. The conceptual model depicts the key elements of fatigue in FM from a patient perspective. This includes: an overwhelming feeling of tiredness (n = 17, 42.5%), not relieved by resting/sleeping (n = 15, 37.5%), not proportional to effort exerted (n = 25, 62.5%), associated with a feeling of weakness/heaviness (n = 20, 50%), interferes with motivation (n = 22, 55%), interferes with desired activities (n = 27, 67.5%), prolongs tasks (n = 15, 37.5%), and makes it difficult to concentrate (n = 21, 52.5%), think clearly (n = 12, 30%) or remember things (n = 9, 22.5%). Conclusion The majority of individuals with FM who participated in this study experience fatigue and describe it as more severe than normal tiredness.http://deepblue.lib.umich.edu/bitstream/2027.42/112483/1/12891_2010_Article_962.pd

A study of cyber hate on Twitter with implications for social media governance strategies

This paper explores ways in which the harmful effects of cyber hate may be mitigated through mechanisms for enhancing the self-governance of new digital spaces. We report findings from a mixed methods study of responses to cyber hate posts, which aimed to: (i) understand how people interact in this context by undertaking qualitative interaction analysis and developing a statistical model to explain the volume of responses to cyber hate posted to Twitter, and (ii) explore use of machine learning techniques to assist in identifying cyber hate counter-speech

Sources of Airborne Endotoxins in Ambient Air and Exposure of Nearby Communities—A Review

Endotoxin is a bioaerosol component that is known to cause respiratory effects in exposed populations. To date, most research focused on occupational exposure, whilst much less is known about the impact of emissions from industrial operations on downwind endotoxin concentrations. A review of the literature was undertaken, identifying studies that reported endotoxin concentrations in both ambient environments and around sources with high endotoxin emissions. Ambient endotoxin concentrations in both rural and urban areas are generally below 10 endotoxin units (EU) m−3; however, around significant sources such as compost facilities, farms, and wastewater treatment plants, endotoxin concentrations regularly exceeded 100 EU m−3. However, this is affected by a range of factors including sampling approach, equipment, and duration. Reported downwind measurements of endotoxin demonstrate that endotoxin concentrations can remain above upwind concentrations. The evaluation of reported data is complicated due to a wide range of different parameters including sampling approaches, temperature, and site activity, demonstrating the need for a standardised methodology and improved guidance. Thorough characterisation of ambient endotoxin levels and modelling of endotoxin from pollution sources is needed to help inform future policy and support a robust health-based risk assessment process

Millihertz X-ray variability during the 2019 outburst of black hole candidate Swift~J1357.2−-0933

Swift J1357.2$-$0933 is a black-hole candidate X-ray transient, which underwent its third outburst in 2019, during which several multi-wavelength observations were carried out.~Here, we report results from the \emph{Neil Gehrels Swift} and \emph{NICER} observatories and radio data from \emph{AMI}.~For the first time,~millihertz quasi-periodic X-ray oscillations with frequencies varying between ${\sim}$~1--5~$\rm{mHz}$ were found in \emph{NICER} observations and a similar feature was also detected in one \emph{Swift}--\textsc{XRT} dataset.~Our spectral analysis indicate that the maximum value of the measured X-ray flux is much lower compared to the peak values observed during the 2011 and 2017 outbursts.~This value is ${\sim}$~100 times lower than found with \emph{MAXI} on MJD~58558 much ($\sim$~68 days) earlier in the outburst, suggesting that the \emph{Swift} and \emph{NICER} fluxes belong to the declining phase of the 2019 outburst.~An additional soft component was detected in the \textsc{XRT} observation with the highest flux level, but at a relatively low $L_{\rm X}$~$\sim$~$3{\times}10^{34}~(d/{\rm 6~kpc)}^2\rm{erg}~\rm{s}^{-1}$, and which we fitted with a disc component at a temperature of $\sim 0.17$~keV.~The optical/UV magnitudes obtained from \emph{Swift}--\textsc{UVOT} showed a correlation with X-ray observations, indicating X-ray reprocessing to be the plausible origin of the optical and UV emission.~However, the source was not significantly detected in the radio band.~There are currently a number of models that could explain this millihertz-frequency X-ray variability; not least of which involves an X-ray component to the curious dips that, so far, have only been observed in the optical.Comment: 14 pages, Accepted for publication in MNRA

The effect of a startle-eliciting device on the foraging success of individual harbor seals (Phoca vitulina)

Pinniped predation on commercially and ecologically important prey has been a source of conflict for centuries. In the Salish Sea, harbor seals (Phoca vitulina) are suspected of impeding the recovery of culturally and ecologically critical Pacific salmon (Oncorhynchus spp.). In Fall 2020, a novel deterrent called Targeted Acoustic Startle Technology (TAST) was deployed at Whatcom Creek to deter harbor seals from preying on fall runs of hatchery chum (O. keta) and Chinook (O. tshawytscha) salmon in Bellingham, Washington, USA. Field observations were conducted in 2020 to compare the presence and foraging success of individual harbor seals across sound exposure (TAST-on) and control (TAST-off) conditions. Observations conducted the previous (2019) and following (2021) years were used to compare the effects observed in 2020 to two control years. Using photo-identification, individual seals were associated with foraging successes across all 3 years of the study. Generalized linear mixed models showed a significant 45.6% reduction in the duration (min) individuals remained at the creek with TAST on, and a significant 43.8% reduction in the overall foraging success of individuals. However, the observed effect of TAST varied across individual seals. Seals that were observed regularly within one season were more likely to return the year after, regardless of TAST treatment. Generalized linear models showed interannual variation in the number of seals present and salmon consumed. However, the effect of TAST in 2020 was greater than the observed variation across years. Our analyses suggest TAST can be an effective tool for managing pinniped predation, although alternate strategies such as deploying TAST longer-term and using multi-unit setups to increase coverage could help strengthen its effects. Future studies should further examine the individual variability found in this study.Peer reviewe

Competing Conservation Objectives for Predators and Prey: Estimating Killer Whale Prey Requirements for Chinook Salmon

Ecosystem-based management (EBM) of marine resources attempts to conserve interacting species. In contrast to single-species fisheries management, EBM aims to identify and resolve conflicting objectives for different species. Such a conflict may be emerging in the northeastern Pacific for southern resident killer whales (Orcinus orca) and their primary prey, Chinook salmon (Oncorhynchus tshawytscha). Both species have at-risk conservation status and transboundary (Canada–US) ranges. We modeled individual killer whale prey requirements from feeding and growth records of captive killer whales and morphometric data from historic live-capture fishery and whaling records worldwide. The models, combined with caloric value of salmon, and demographic and diet data for wild killer whales, allow us to predict salmon quantities needed to maintain and recover this killer whale population, which numbered 87 individuals in 2009. Our analyses provide new information on cost of lactation and new parameter estimates for other killer whale populations globally. Prey requirements of southern resident killer whales are difficult to reconcile with fisheries and conservation objectives for Chinook salmon, because the number of fish required is large relative to annual returns and fishery catches. For instance, a U.S. recovery goal (2.3% annual population growth of killer whales over 28 years) implies a 75% increase in energetic requirements. Reducing salmon fisheries may serve as a temporary mitigation measure to allow time for management actions to improve salmon productivity to take effect. As ecosystem-based fishery management becomes more prevalent, trade-offs between conservation objectives for predators and prey will become increasingly necessary. Our approach offers scenarios to compare relative influence of various sources of uncertainty on the resulting consumption estimates to prioritise future research efforts, and a general approach for assessing the extent of conflict between conservation objectives for threatened or protected wildlife where the interaction between affected species can be quantified

Containment of socially optimal policies in multiple-facility Markovian queueing systems

We consider a Markovian queueing system with N heterogeneous service facilities, each of which has multiple servers available, linear holding costs, a fixed value of service and a first-come-first-serve queue discipline. Customers arriving in the system can be either rejected or sent to one of the N facilities. Two different types of control policies are considered, which we refer to as ‘selfishly optimal’ and ‘socially optimal’. We prove the equivalence of two different Markov Decision Process formulations, and then show that classical M/M/1 queue results from the early literature on behavioural queueing theory can be generalized to multiple dimensions in an elegant way. In particular, the state space of the continuous-time Markov process induced by a socially optimal policy is contained within that of the selfishly optimal policy. We also show that this result holds when customers are divided into an arbitrary number of heterogeneous classes, provided that the service rates remain non-discriminatory

Gut microbiome composition in the Hispanic Community Health Study/Study of Latinos is shaped by geographic relocation, environmental factors, and obesity.

Background: Hispanics living in the USA may have unrecognized potential birthplace and lifestyle influences on the gut microbiome. We report a cross-sectional analysis of 1674 participants from four centers of the Hispanic Community Health Study/Study of Latinos (HCHS/SOL), aged 18 to 74 years old at recruitment.Results: Amplicon sequencing of 16S rRNA gene V4 and fungal ITS1 fragments from self-collected stool samples indicate that the host microbiome is determined by sociodemographic and migration-related variables. Those who relocate from Latin America to the USA at an early age have reductions in Prevotella to Bacteroides ratios that persist across the life course. Shannon index of alpha diversity in fungi and bacteria is low in those who relocate to the USA in early life. In contrast, those who relocate to the USA during adulthood, over 45 years old, have high bacterial and fungal diversity and high Prevotella to Bacteroides ratios, compared to USA-born and childhood arrivals. Low bacterial diversity is associated in turn with obesity. Contrasting with prior studies, our study of the Latino population shows increasing Prevotella to Bacteroides ratio with greater obesity. Taxa within Acidaminococcus, Megasphaera, Ruminococcaceae, Coriobacteriaceae, Clostridiales, Christensenellaceae, YS2 (Cyanobacteria), and Victivallaceae are significantly associated with both obesity and earlier exposure to the USA, while Oscillospira and Anaerotruncus show paradoxical associations with both obesity and late-life introduction to the USA.Conclusions: Our analysis of the gut microbiome of Latinos demonstrates unique features that might be responsible for health disparities affecting Hispanics living in the USA

Red Sea SAR11 and Prochlorococcus Single-cell Genomes Reflect Globally Distributed Pangenomes

Evidence suggests many marine bacteria are cosmopolitan, with widespread but sparse strains poised to seed abundant populations under conducive growth conditions. However, studies supporting this "microbial seed bank" hypothesis have analyzed taxonomic marker genes rather than whole genomes/metagenomes, leaving open the possibility that disparate ocean regions harbor endemic gene content. The Red Sea is isolated geographically from the rest of the ocean and has a combination of high irradiance, high temperature, and high salinity that is unique among the oceans; we therefore asked whether it harbors endemic gene content. We sequenced and assembled single-cell genomes of 21 SAR11 (subclades Ia, Ib, Id, and II) and 5 Prochlorococcus (ecotype HLII) samples from the Red Sea and combined them with globally sourced reference genomes to cluster genes into ortholog groups (OGs). Ordination of OG composition could distinguish clades, including phylogenetically cryptic Prochlorococcus ecotypes LLII and LLIII. Compared with reference genomes, 1% of Prochlorococcus and 17% of SAR11 OGs were unique to the Red Sea genomes (RS-OGs). Most (83%) RS-OGs had no annotated function, but 65% of RS-OGs were expressed in diel Red Sea metatranscriptomes, suggesting they are functional. Searching Tara Oceans metagenomes, RS-OGs were as likely to be found as non-RS-OGs; nevertheless, Red Sea and other warm samples could be distinguished from cooler samples using the relative abundances of OGs. The results suggest that the prevalence of OGs in these surface ocean bacteria is largely cosmopolitan, with differences in population metagenomes manifested by differences in relative abundance rather than complete presence/absence of OGs.IMPORTANCE Studies have shown that as we sequence seawater from a selected environment deeper and deeper, we approach finding every bacterial taxon known for the ocean as a whole. However, such studies have focused on taxonomic marker genes rather than on whole genomes, raising the possibility that the lack of endemism results from the method of investigation. We took a geographically isolated water body, the Red Sea, and sequenced single cells from it. We compared those single-cell genomes to available genomes from around the ocean and to ocean-spanning metagenomes. We showed that gene ortholog groups found in Red Sea genomes but not in other genomes are nevertheless common across global ocean metagenomes. These results suggest that Baas Becking's hypothesis "everything is everywhere, but the environment selects" also applies to gene ortholog groups. This widely dispersed functional diversity may give oceanic microbial communities the functional capacity to respond rapidly to changing conditions