870 research outputs found
HLA epitope mismatch in haploidentical transplantation is associated with decreased relapse and delayed engraftment
Contribution of Heat Fluxes on Cyclone Narelle as Simulated by a Mesoscale Model
- Heat fluxes from oceanic evaporation particularly latent heat is important to drive the formation and intensification of Cyclone Narelle. The research was carried out by introducing a mesoscale model, namely Weather and Research Forecasting (WRF). One domain with spatial resolution at 10 km was utilized in the model. The model involved significant physical parameters, e.g., Kain-Fritsch in the cumulus scheme, Yonsei University in the Planetary Boundary Layer scheme, and WRF Single-Moment 3-class in the microphysics scheme. The analysis focused on January 8th to 14th upon all stages of Narelle. The result showed that Sea Surface Temperatures (SST) higher than 26°C was a favorable environment for Cylone Narelle to form. Surface sensible and latent heat fluxes have strong positive correlation with wind speed and SST. It can be concluded that these variables were highly correlated with surface heat flux that further lead to the formation and intensification of Cyclone Narelle in early January 2013 over South Indian Ocean. The tracks and stages of the model are nearly similar to the observations, the differences are found in late phases of Narelle
A Novel Energy-Efficient Reservation System for Edge Computing in 6G Vehicular Ad Hoc Network
The roadside unit (RSU) is one of the fundamental components in a vehicular ad hoc network (VANET), where a vehicle communicates in infrastructure mode. The RSU has multiple functions, including the sharing of emergency messages and the updating of vehicles about the traffic situation. Deploying and managing a static RSU (sRSU) requires considerable capital and operating expenditures (CAPEX and OPEX), leading to RSUs that are sparsely distributed, continuous handovers amongst RSUs, and, more importantly, frequent RSU interruptions. At present, researchers remain focused on multiple parameters in the sRSU to improve the vehicle-to-infrastructure (V2I) communication; however, in this research, the mobile RSU (mRSU), an emerging concept for sixth-generation (6G) edge computing vehicular ad hoc networks (VANETs), is proposed to improve the connectivity and efficiency of communication among V2I. In addition to this, the mRSU can serve as a computing resource for edge computing applications. This paper proposes a novel energy-efficient reservation technique for edge computing in 6G VANETs that provides an energy-efficient, reservation-based, cost-effective solution by introducing the concept of the mRSU. The simulation outcomes demonstrate that the mRSU exhibits superior performance compared to the sRSU in multiple aspects. The mRSU surpasses the sRSU with a packet delivery ratio improvement of 7.7%, a throughput increase of 5.1%, a reduction in end-to-end delay by 4.4%, and a decrease in hop count by 8.7%. The results are generated across diverse propagation models, employing realistic urban scenarios with varying packet sizes and numbers of vehicles. However, it is important to note that the enhanced performance parameters and improved connectivity with more nodes lead to a significant increase in energy consumption by 2%
Patterns of Political Communication Between Government Institutions and Effect to the Trust of the Acehnese People
This study has described how the pattern of political communication between government institutions and its impact on public confidence in development in Aceh Province, Indonesia. This study focuses more on the analysis of communication patterns between the executive (ie: Governor of Aceh Province) and the legislative (DPR) in carrying out their respective duties and functions in the context of development in Aceh Province, Indonesia. This study uses a descriptive qualitative approach aimed at describing the pattern of political communication between government institutions and analyzing the level of trust of the Acehnese people. The benefit of this study is to provide a formula for good and effective political communication with elites at various levels of institutions from the executive to the legislature. Based on the results of the study, it can be concluded that the patterns of political communication between government institutions, namely the executive and legislative institutions, are personal communication patterns, informal communication patterns, family communication patterns, party or organizational communication patterns. All types of communication patterns are carried out between parties in carrying out interest lobbying and development policies in the Aceh Province, Indonesia. This type of communication pattern, based on the results of research, has been carried out by both parties in running government institutions in Aceh, namely the Aceh Government and the Aceh Legislature
CMSSM Spectroscopy in light of PAMELA and ATIC
Dark matter neutralinos in the constrained minimal supersymmetric model
(CMSSM) may account for the recent cosmic ray electron and positron
observations reported by the PAMELA and ATIC experiments either through self
annihilation or via decay. However, to achieve this, both scenarios require new
physics beyond the 'standard' CMSSM, and a unified explanation of the two
experiments suggests a neutralino mass of order 700 GeV - 2 TeV. A relatively
light neutralino with mass around 100 GeV (300 GeV) can accomodate the PAMELA
but not the ATIC observations based on a model of annihilating (decaying)
neutralinos. We study the implications of these scenarios for Higgs and
sparticle spectroscopy in the CMSSM and highlight some benchmark points. An
estimate of neutrino flux expected from the annihilating and decaying
neutralino scenarios is provided.Comment: 14 pages, 8 figures, 2 tables; References added; color coding fixed
in some figure
Behaviour of non-donor specific antibodies during rapid re-synthesis of donor specific HLA antibodies after antibody incompatible renal transplantation
Background:
HLA directed antibodies play an important role in acute and chronic allograft rejection. During viral infection of a patient with HLA antibodies, the HLA antibody levels may rise even though there is no new immunization with antigen. However it is not known whether the converse occurs, and whether changes on non-donor specific antibodies are associated with any outcomes following HLA antibody incompatible renal transplantation.
Methods:
55 patients, 31 women and 24 men, who underwent HLAi renal transplant in our center from September 2005 to September 2010 were included in the studies. We analysed the data using two different approaches, based on; i) DSA levels and ii) rejection episode post transplant. HLA antibody levels were measured during the early post transplant period and corresponding CMV, VZV and Anti-HBs IgG antibody levels and blood group IgG, IgM and IgA antibodies were quantified.
Results:
Despite a significant DSA antibody rise no significant non-donor specific HLA antibody, viral or blood group antibody rise was found. In rejection episode analyses, multiple logistic regression modelling showed that change in the DSA was significantly associated with rejection (p = 0.002), even when adjusted for other antibody levels. No other antibody levels were predictive of rejection. Increase in DSA from pre treatment to a post transplant peak of 1000 was equivalent to an increased chance of rejection with an odds ratio of 1.47 (1.08, 2.00).
Conclusion:
In spite of increases or decreases in the DSA levels, there were no changes in the viral or the blood group antibodies in these patients. Thus the DSA rise is specific in contrast to the viral, blood group or third party antibodies post transplantation. Increases in the DSA post transplant in comparison to pre-treatment are strongly associated with occurrence of rejection
Patterns of infectious complications in acute myeloid leukemia and myelodysplastic syndromes patients treated with 10-day decitabine regimen
The CIRDO Corpus: Comprehensive Audio/Video Database of Domestic Falls of Elderly People
International audienceAmbient Assisted Living aims at enhancing the quality of life of older and disabled people at home thanks to Smart Homes. In particular, regarding elderly living alone at home, the detection of distress situation after a fall is very important to reassure this kind of population. However, many studies do not include tests in real settings, because data collection in this domain is very expensive and challenging and because of the few available data sets. The CIRDOcorpus is a dataset recorded in realistic conditions in DOMUS, a fully equipped Smart Home with microphones and home automation sensors, in which participants performed scenarios including real falls on a carpet and calls for help. These scenarios were elaborated thanks to a field study involving elderly persons. Experiments related in a first part to distress detection in real-time using audio and speech analysis and in a second part to fall detection using video analysis are presented. Results show the difficulty of the task. The database can be used as standardized database by researchers to evaluate and compare their systems for elderly person's assistance. Keywords: audio and video data set, multimodal corpus, natural language and multimodal interaction, Ambient Assisted Living (AAL), distress situation
Microbe-citric acid assisted phytoremediation of chromium by castor bean (Ricinus communis L.)
Chromium is one of the highly toxic heavy metals to plant growth and development especially hexavalent chromium (Cr+6) due to its readily available nature and mobility into the environment. The chelating agents and hyperaccumulator plant can contribute to remediating the heavy metals from the contaminated medium. This study was conducted to analyze the role of citric acid and chromium resistant bacteria in castor bean to remediate Cr+6 from the polluted soil. The soil was spiked with different levels of citric acid (0, 2.5, 5 mM) and chromium (0, 10, 20 mg kg−1). The ripened plants were harvested and analyzed for growth parameters, chlorophyll contents, gas exchange parameters, oxidative stress markers, antioxidant enzymes activities and chromium accumulation in different parts of plants. The high concentration of chromium 20 mg kg−1 drastically reduced the plant growth, decreased photosynthetic rate and increased oxidative stress. The application of CA improved the plant growth even at the highest concentration of chromium which was further boosted by the combined application of CA and chromium resistant bacteria. However, the performance of staphylococcus aureus was found significantly better than Bacillus subtilis due to its better ability to tolerate chromium toxicity even at high concentrations. The findings proved that castor bean has excellent potential to tolerate high chromium concentrations and can be effectively used to remediate metals contaminated soil. Further, CA and metal resistant bacteria can significantly enhance the phytoremediation potential of castor bean and other hyperaccumulator plants. The bacteria assisted phytoremediation coupled with the chelating agent can be a practical approach to remediate the metals contaminating soils
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